Gene Review:
src - p60-SRC phosphoprotein
Rous sarcoma virus
- Hormonal regulation of the Rous sarcoma virus src gene via a heterologous promoter defines a threshold dose for cellular transformation. Jakobovits, E.B., Majors, J.E., Varmus, H.E. Cell (1984)
- Characterization of protein kinase activity associated with the transforming gene product of Fujinami sarcoma virus. Feldman, R.A., Hanafusa, T., Hanafusa, H. Cell (1980)
- Identification of a transformation-specific protein induced by a Rous sarcoma virus. Jay, G., Shiu, R.P., Jay, F.T., Levine, A.S., Pastan, I. Cell (1978)
- No expression of a Rous sarcoma virus-induced tumor antigen in mammalian cells infected with retroviruses transducing other oncogenes of the src gene family. Kuzumaki, N., Yamagiwa, S., Oikawa, T. J. Natl. Cancer Inst. (1985)
- Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor. Resh, M.D. Cell (1989)
- Effect of src infection on long-term marrow cultures: increased self-renewal of hemopoietic progenitor cells without leukemia. Boettiger, D., Anderson, S., Dexter, T.M. Cell (1984)
- Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src. Snyder, M.A., Bishop, J.M., Colby, W.W., Levinson, A.D. Cell (1983)
- Nucleotide sequence of Rous sarcoma virus. Schwartz, D.E., Tizard, R., Gilbert, W. Cell (1983)
- Transforming proteins of some feline and avian sarcoma viruses are related structurally and functionally. Beemon, K. Cell (1981)
- Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins. Moelling, K., Heimann, B., Beimling, P., Rapp, U.R., Sander, T. Nature (1984)
- Mapping oligonucleotides of Rous sarcoma virus RNA that segregate with polymerase and group-specific antigen markers in recombinants. Wang, L., Galehouse, D., Mellon, P., Duesberg, P., Mason, W.S., Vogt, P.K. Proc. Natl. Acad. Sci. U.S.A. (1976)
- Characterization of the protein kinase activity of avian sarcoma virus src gene product. Maness, P.F., Engeser, H., Greenberg, M.E., O'Farrell, M., Gall, W.E., Edelman, G.M. Proc. Natl. Acad. Sci. U.S.A. (1979)
- Amino acid alterations within a highly conserved region of the Rous sarcoma virus src gene product pp60src inactivate tyrosine protein kinase activity. Bryant, D.L., Parsons, J.T. Mol. Cell. Biol. (1984)
- Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Levinson, A.D., Oppermann, H., Levintow, L., Varmus, H.E., Bishop, J.M. Cell (1978)
- Molecular cloning and characterization of the chicken gene homologous to the transforming gene of Rous sarcoma virus. Shalloway, D., Zelenetz, A.D., Cooper, G.M. Cell (1981)
- Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases. Hughes, S.H., Payvar, F., Spector, D., Schimke, R.T., Robinson, H.L., Payne, G.S., Bishop, J.M., Varmus, H.E. Cell (1979)
- Myelin-associated glycoprotein, a cell adhesion molecule of oligodendrocytes, is phosphorylated in brain. Edwards, A.M., Arquint, M., Braun, P.E., Roder, J.C., Dunn, R.J., Pawson, T., Bell, J.C. Mol. Cell. Biol. (1988)
- Transformation by Rous sarcoma virus: a cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine. Radke, K., Gilmore, T., Martin, G.S. Cell (1980)
- Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity. Krueger, J.G., Garber, E.A., Goldberg, A.R., Hanafusa, H. Cell (1982)
- Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene. Alemà, S., Casalbore, P., Agostini, E., Tatò, F. Nature (1985)
- Immunoprecipitation of insulin receptors from cultured human lymphocytes (IM-9 cells) by antibodies to pp60src. Perrotti, N., Taylor, S.I., Richert, N.D., Rapp, U.R., Pastan, I.H., Roth, J. Science (1985)
- Association of p60c-src with polyoma virus middle-T antigen abrogating mitosis-specific activation. Kaech, S., Covic, L., Wyss, A., Ballmer-Hofer, K. Nature (1991)
- Construction of plasmids for expression of Rous sarcoma virus transforming protein, p60src, in Escherichia coli. Gilmer, T.M., Parsons, J.T., Erikson, R.L. Proc. Natl. Acad. Sci. U.S.A. (1982)
- NH2-terminal sequences of two src proteins that cause aberrant transformation. Garber, E.A., Hanafusa, H. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblasts. Linder, M.E., Burr, J.G. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Xie, W.L., Chipman, J.G., Robertson, D.L., Erikson, R.L., Simmons, D.L. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Immunofluorescence on avian sarcoma virus-transformed cells: localization of the src gene product. Rohrschneider, L.R. Cell (1979)
- Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry. Willingham, M.C., Jay, G., Pastan, I. Cell (1979)
- Purification of the Rous sarcoma virus src kinase by casein-agarose and tyrosine-agarose affinity chromatography. Fukami, Y., Lipmann, F. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Comparison between the viral transforming gene (src) of recovered avian sarcoma virus and its cellular homolog. Takeya, T., Hanafusa, H., Junghans, R.P., Ju, G., Skalka, A.M. Mol. Cell. Biol. (1981)