Gene Review:
CYP4A11 - cytochrome P450, family 4, subfamily A,...
Homo sapiens
Synonyms:
20-HETE synthase, 20-hydroxyeicosatetraenoic acid synthase, CP4Y, CYP4A2, CYP4AII, ...
- Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. Kawashima, H., Naganuma, T., Kusunose, E., Kono, T., Yasumoto, R., Sugimura, K., Kishimoto, T. Arch. Biochem. Biophys. (2000)
- Associations between human liver and kidney cadmium content and immunochemically detected CYP4A11 apoprotein. Baker, J.R., Satarug, S., Urbenjapol, S., Edwards, R.J., Williams, D.J., Moore, M.R., Reilly, P.E. Biochem. Pharmacol. (2002)
- CYP4A11 is repressed by retinoic acid in human liver cells. Antoun, J., Amet, Y., Simon, B., Dréano, Y., Corlu, A., Corcos, L., Salaun, J.P., Plée-Gautier, E. FEBS Lett. (2006)
- Potential for early involvement of CYP isoforms in aspects of human cadmium toxicity. Baker, J.R., Satarug, S., Edwards, R.J., Moore, M.R., Williams, D.J., Reilly, P.E. Toxicol. Lett. (2003)
- Autocatalytic mechanism and consequences of covalent heme attachment in the cytochrome P4504A family. LeBrun, L.A., Hoch, U., Ortiz de Montellano, P.R. J. Biol. Chem. (2002)
- Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression. Park, S.H., Waxman, D.J. J. Biol. Chem. (2001)
- Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11. Lasker, J.M., Chen, W.B., Wolf, I., Bloswick, B.P., Wilson, P.D., Powell, P.K. J. Biol. Chem. (2000)
- The catalytic site of cytochrome P4504A11 (CYP4A11) and its L131F mutant. Dierks, E.A., Zhang, Z., Johnson, E.F., de Montellano, P.R. J. Biol. Chem. (1998)
- Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy. Mayer, B., Lieb, W., Götz, A., König, I.R., Aherrahrou, Z., Thiemig, A., Holmer, S., Hengstenberg, C., Doering, A., Loewel, H., Hense, H.W., Schunkert, H., Erdmann, J. Hypertension (2005)
- Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes. Powell, P.K., Wolf, I., Lasker, J.M. Arch. Biochem. Biophys. (1996)
- Complete cDNA sequence and cDNA-directed expression of CYP4A11, a fatty acid omega-hydroxylase expressed in human kidney. Imaoka, S., Ogawa, H., Kimura, S., Gonzalez, F.J. DNA Cell Biol. (1993)
- Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs. Bell, D.R., Plant, N.J., Rider, C.G., Na, L., Brown, S., Ateitalla, I., Acharya, S.K., Davies, M.H., Elias, E., Jenkins, N.A. Biochem. J. (1993)
- Cytochrome P450 4A11 expression in human keratinocytes: effects of ultraviolet irradiation. Gonzalez, M.C., Marteau, C., Franchi, J., Migliore-Samour, D. Br. J. Dermatol. (2001)
- Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. Lee, A.J., Cai, M.X., Thomas, P.E., Conney, A.H., Zhu, B.T. Endocrinology (2003)
- Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11. Powell, P.K., Wolf, I., Jin, R., Lasker, J.M. J. Pharmacol. Exp. Ther. (1998)
- Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone. Savas, U., Hsu, M.H., Johnson, E.F. Arch. Biochem. Biophys. (2003)
- Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties. Hellmold, H., Rylander, T., Magnusson, M., Reihnér, E., Warner, M., Gustafsson, J.A. J. Clin. Endocrinol. Metab. (1998)
- Cytochromes P450 are differently expressed in normal and varicose human saphenous veins: linkage with varicosis. Bertrand-Thiebault, C., Ferrari, L., Boutherin-Falson, O., Kockx, M., Desquand-Billiald, S., Fichelle, J.M., Nottin, R., Renaud, J.F., Batt, A.M., Visvikis, S. Clin. Exp. Pharmacol. Physiol. (2004)
- Expression of glutathione-dependent enzymes and cytochrome P450s in freshly isolated and primary cultures of proximal tubular cells from human kidney. Cummings, B.S., Lasker, J.M., Lash, L.H. J. Pharmacol. Exp. Ther. (2000)
- Characterization of the CYP4A11 gene, a second CYP4A gene in humans. Bellamine, A., Wang, Y., Waterman, M.R., Gainer, J.V., Dawson, E.P., Brown, N.J., Capdevila, J.H. Arch. Biochem. Biophys. (2003)