Gene Review:
Npy5r - neuropeptide Y receptor Y5
Mus musculus
Synonyms:
NPY-Y5 receptor, NPY5-R, NPYY5-R, Neuropeptide Y receptor type 5, Npy5, ...
Lee,
Michalkiewicz,
Kitlinska,
Kalezic,
Switalska,
Yoo,
Sangkharat,
Ji,
Li,
Michalkiewicz,
Ljubisavljevic,
Johansson,
Grant,
Zukowska,
Ishihara,
Kanatani,
Mashiko,
Tanaka,
Hidaka,
Gomori,
Iwaasa,
Murai,
Egashira,
Murai,
Mitobe,
Matsushita,
Okamoto,
Sato,
Jitsuoka,
Fukuroda,
Ohe,
Guan,
Macneil,
Van der Ploeg,
Nishikibe,
Ishii,
Ihara,
Fukami,
Thiele,
Miura,
Marsh,
Bernstein,
Palmiter,
Borowsky,
Walker,
Bard,
Weinshank,
Laz,
Vaysse,
Branchek,
Gerald,
Fetissov,
Byrne,
Hassani,
Ernfors,
Hökfelt,
Nakamura,
Yokoyama,
Watanabe,
Matsumoto,
- Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. Raposinho, P.D., Pedrazzini, T., White, R.B., Palmiter, R.D., Aubert, M.L. Endocrinology (2004)
- A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice. Ishihara, A., Kanatani, A., Mashiko, S., Tanaka, T., Hidaka, M., Gomori, A., Iwaasa, H., Murai, N., Egashira, S., Murai, T., Mitobe, Y., Matsushita, H., Okamoto, O., Sato, N., Jitsuoka, M., Fukuroda, T., Ohe, T., Guan, X., Macneil, D.J., Van der Ploeg, L.H., Nishikibe, M., Ishii, Y., Ihara, M., Fukami, T. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Neuropeptide-Y Y5 receptors modulate the onset and maintenance of operant ethanol self-administration. Schroeder, J.P., Iller, K.A., Hodge, C.W. Alcohol. Clin. Exp. Res. (2003)
- Role of the Y5 neuropeptide Y receptor in feeding and obesity. Marsh, D.J., Hollopeter, G., Kafer, K.E., Palmiter, R.D. Nat. Med. (1998)
- Neuropeptide Y induces ischemic angiogenesis and restores function of ischemic skeletal muscles. Lee, E.W., Michalkiewicz, M., Kitlinska, J., Kalezic, I., Switalska, H., Yoo, P., Sangkharat, A., Ji, H., Li, L., Michalkiewicz, T., Ljubisavljevic, M., Johansson, H., Grant, D.S., Zukowska, Z. J. Clin. Invest. (2003)
- Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor. Criscione, L., Rigollier, P., Batzl-Hartmann, C., Rüeger, H., Stricker-Krongrad, A., Wyss, P., Brunner, L., Whitebread, S., Yamaguchi, Y., Gerald, C., Heurich, R.O., Walker, M.W., Chiesi, M., Schilling, W., Hofbauer, K.G., Levens, N. J. Clin. Invest. (1998)
- Role of the Y5 neuropeptide Y receptor in limbic seizures. Marsh, D.J., Baraban, S.C., Hollopeter, G., Palmiter, R.D. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Evolution of the neuropeptide Y receptor family: gene and chromosome duplications deduced from the cloning and mapping of the five receptor subtype genes in pig. Wraith, A., Törnsten, A., Chardon, P., Harbitz, I., Chowdhary, B.P., Andersson, L., Lundin, L.G., Larhammar, D. Genome Res. (2000)
- Molecular cloning, organization and localization of the gene for the mouse neuropeptide Y-Y5 receptor. Nakamura, M., Yokoyama, M., Watanabe, H., Matsumoto, T. Biochim. Biophys. Acta (1997)
- Y5 receptors mediate neuropeptide Y actions at excitatory synapses in area CA3 of the mouse hippocampus. Guo, H., Castro, P.A., Palmiter, R.D., Baraban, S.C. J. Neurophysiol. (2002)
- Characterization of neuropeptide Y (NPY) Y5 receptor-mediated obesity in mice: chronic intracerebroventricular infusion of D-Trp(34)NPY. Mashiko, S., Ishihara, A., Iwaasa, H., Sano, H., Oda, Z., Ito, J., Yumoto, M., Okawa, M., Suzuki, J., Fukuroda, T., Jitsuoka, M., Morin, N.R., MacNeil, D.J., Van der Ploeg, L.H., Ihara, M., Fukami, T., Kanatani, A. Endocrinology (2003)
- Characterization of neuropeptide Y Y2 and Y5 receptor expression in the mouse hypothalamus. Fetissov, S.O., Byrne, L.C., Hassani, H., Ernfors, P., Hökfelt, T. J. Comp. Neurol. (2004)
- Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon. Goumain, M., Voisin, T., Lorinet, A.M., Laburthe, M. Biochem. Biophys. Res. Commun. (1998)
- Down-regulated NPY receptor subtype-5 mRNA expression in genetically obese mouse brain. Xin, X.G., Huang, X.F. Neuroreport (1998)
- Molecular biology and pharmacology of multiple NPY Y5 receptor species homologs. Borowsky, B., Walker, M.W., Bard, J., Weinshank, R.L., Laz, T.M., Vaysse, P., Branchek, T.A., Gerald, C. Regul. Pept. (1998)
- Central NPY receptor-mediated alteration of heart rate dynamics in mice during expression of fear conditioned to an auditory cue. Tovote, P., Meyer, M., Beck-Sickinger, A.G., von Hörsten, S., Ove Ogren, S., Spiess, J., Stiedl, O. Regul. Pept. (2004)
- Energy metabolic profile of mice after chronic activation of central NPY Y1, Y2, or Y5 receptors. Henry, M., Ghibaudi, L., Gao, J., Hwa, J.J. Obes. Res. (2005)
- Neurobiological responses to ethanol in mutant mice lacking neuropeptide Y or the Y5 receptor. Thiele, T.E., Miura, G.I., Marsh, D.J., Bernstein, I.L., Palmiter, R.D. Pharmacol. Biochem. Behav. (2000)
- Y1-receptors regulate the expression of Y2-receptors in distinct mouse forebrain areas. Wittmann, W., Loacker, S., Kapeller, I., Herzog, H., Schwarzer, C. Neuroscience (2005)