Gene Review:
Pklr - pyruvate kinase, liver and RBC
Rattus norvegicus
Synonyms:
L-PK, PK1, PKL, Pklg, Pyruvate kinase PKLR, ...
- Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene. Krones, A., Jungermann, K., Kietzmann, T. Endocrinology (2001)
- Alteration in L-type pyruvate kinase gene expression is not associated with the LF-B1 mRNA level. Imai, E., Noguchi, T., Takenaka, M., Yamada, K., Matsuda, T., Monaci, P., Nicosia, A., Tanaka, T. Biochem. Biophys. Res. Commun. (1991)
- Upstream stimulatory factor-2 (USF2) activity is required for glucose stimulation of L-pyruvate kinase promoter activity in single living islet beta-cells. Kennedy, H.J., Viollet, B., Rafiq, I., Kahn, A., Rutter, G.A. J. Biol. Chem. (1997)
- Pyruvate kinase isoenzymes in altered foci and carcinoma of rat liver. Reinacher, M., Eigenbrodt, E., Gerbracht, U., Zenk, G., Timmermann-Trosiener, I., Bentley, P., Waechter, F., Schulte-Hermann, R. Carcinogenesis (1986)
- Cytoimmunochemical study of pyruvate kinase isoenzymes in rat liver. Gali, P., Hartmann, L. Liver (1982)
- A mouse homolog to the avian sarcoma virus src protein is a member of a protein kinase cascade. Spector, M., Pepinsky, R.B., Vogt, V.M., Racker, E. Cell (1981)
- Decrease in L-type pyruvate kinase activity in rat liver by some promoters of hepatocarcinogenesis. Yanagi, S., Sakamoto, M., Ninomiya, Y., Kamiya, T. J. Natl. Cancer Inst. (1984)
- A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Yamashita, H., Takenoshita, M., Sakurai, M., Bruick, R.K., Henzel, W.J., Shillinglaw, W., Arnot, D., Uyeda, K. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Functional characterization of the L-type pyruvate kinase gene glucose response complex. Diaz Guerra, M.J., Bergot, M.O., Martinez, A., Cuif, M.H., Kahn, A., Raymondjean, M. Mol. Cell. Biol. (1993)
- Nuclear factor 1 family members interact with hepatocyte nuclear factor 1alpha to synergistically activate L-type pyruvate kinase gene transcription. Satoh, S., Noaki, T., Ishigure, T., Osada, S., Imagawa, M., Miura, N., Yamada, K., Noguchi, T. J. Biol. Chem. (2005)
- Structure of the rat L-type pyruvate kinase gene. Cognet, M., Lone, Y.C., Vaulont, S., Kahn, A., Marie, J. J. Mol. Biol. (1987)
- Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas. Miquerol, L., Lopez, S., Cartier, N., Tulliez, M., Raymondjean, M., Kahn, A. J. Biol. Chem. (1994)
- Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine-supplemented diet. Hacker, H.J., Steinberg, P., Bannasch, P. Carcinogenesis (1998)
- Identification and characterization of hepatocyte-specific regulatory regions of the rat pyruvate kinase L gene. The synergistic effect of multiple elements. Yamada, K., Noguchi, T., Matsuda, T., Takenaka, M., Monaci, P., Nicosia, A., Tanaka, T. J. Biol. Chem. (1990)
- Regulation of rat hepatic L-pyruvate kinase promoter composition and activity by glucose, n-3 polyunsaturated fatty acids, and peroxisome proliferator-activated receptor-alpha agonist. Xu, J., Christian, B., Jump, D.B. J. Biol. Chem. (2006)
- Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter. Doiron, B., Cuif, M.H., Kahn, A., Diaz-Guerra, M.J. J. Biol. Chem. (1994)
- Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene. Thompson, K.S., Towle, H.C. J. Biol. Chem. (1991)
- Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells. Raile, K., Klammt, J., Laue, S., Garten, A., Blüher, M., Kralisch, S., Klöting, N., Kiess, W. Diabetologia (2005)
- Analysis by cell-free transcription of the liver-specific pyruvate kinase gene promoter. Vaulont, S., Puzenat, N., Kahn, A., Raymondjean, M. Mol. Cell. Biol. (1989)
- Carbohydrate regulation of hepatic gene expression. Evidence against a role for the upstream stimulatory factor. Kaytor, E.N., Shih, H., Towle, H.C. J. Biol. Chem. (1997)
- Dephosphorylation of L-pyruvate kinase during rat liver hepatocyte isolation. Riou, J.P., Audigier, C., Laville, M., Beylot, M., Pigeon, P., Mornex, R. Arch. Biochem. Biophys. (1985)