Gene Review:
ASIC1 - acid sensing (proton gated) ion channel 1
Homo sapiens
Synonyms:
ACCN2, ASIC, Acid-sensing ion channel 1, Amiloride-sensitive cation channel 2, neuronal, BNAC2, ...
- Increased acid-sensing ion channel ASIC-3 in inflamed human intestine. Yiangou, Y., Facer, P., Smith, J.A., Sangameswaran, L., Eglen, R., Birch, R., Knowles, C., Williams, N., Anand, P. European journal of gastroenterology & hepatology. (2001)
- Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+. Babinski, K., Catarsi, S., Biagini, G., Séguéla, P. J. Biol. Chem. (2000)
- Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function. Berdiev, B.K., Xia, J., Jovov, B., Markert, J.M., Mapstone, T.B., Gillespie, G.Y., Fuller, C.M., Bubien, J.K., Benos, D.J. J. Biol. Chem. (2002)
- Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Gao, J., Duan, B., Wang, D.G., Deng, X.H., Zhang, G.Y., Xu, L., Xu, T.L. Neuron (2005)
- H(+)-gated cation channels. Waldmann, R., Champigny, G., Lingueglia, E., De Weille, J.R., Heurteaux, C., Lazdunski, M. Ann. N. Y. Acad. Sci. (1999)
- Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Kellenberger, S., Schild, L. Physiol. Rev. (2002)
- A proton-gated cation channel involved in acid-sensing. Waldmann, R., Champigny, G., Bassilana, F., Heurteaux, C., Lazdunski, M. Nature (1997)
- BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. García-Añoveros, J., Derfler, B., Neville-Golden, J., Hyman, B.T., Corey, D.P. Proc. Natl. Acad. Sci. U.S.A. (1997)
- The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory. Wemmie, J.A., Chen, J., Askwith, C.C., Hruska-Hageman, A.M., Price, M.P., Nolan, B.C., Yoder, P.G., Lamani, E., Hoshi, T., Freeman, J.H., Welsh, M.J. Neuron (2002)
- cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1. Leonard, A.S., Yermolaieva, O., Hruska-Hageman, A., Askwith, C.C., Price, M.P., Wemmie, J.A., Welsh, M.J. Proc. Natl. Acad. Sci. U.S.A. (2003)
- The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties. Bassilana, F., Champigny, G., Waldmann, R., de Weille, J.R., Heurteaux, C., Lazdunski, M. J. Biol. Chem. (1997)
- Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury. Poirot, O., Berta, T., Decosterd, I., Kellenberger, S. J. Physiol. (Lond.) (2006)
- Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system. Alvarez de la Rosa, D., Zhang, P., Shao, D., White, F., Canessa, C.M. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line. Gitterman, D.P., Wilson, J., Randall, A.D. J. Physiol. (Lond.) (2005)
- Coexpression of Vanilloid Receptor Subtype-1 and Acid-sensing Ion Channel Genes in the Human Trigeminal Ganglion Neurons. Ugawa, S., Ueda, T., Yamamura, H., Nagao, M., Shimada, S. Chem. Senses (2005)
- Malignant human gliomas express an amiloride-sensitive Na+ conductance. Bubien, J.K., Keeton, D.A., Fuller, C.M., Gillespie, G.Y., Reddy, A.T., Mapstone, T.B., Benos, D.J. Am. J. Physiol. (1999)
- Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells. Agopyan, N., Bhatti, T., Yu, S., Simon, S.A. Toxicol. Appl. Pharmacol. (2003)
- Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF. Catarsi, S., Babinski, K., Séguéla, P. Neuropharmacology (2001)
- Vanilloid type 1 receptor and the acid-sensing ion channel mediate acid phosphate activation of muscle afferent nerves in rats. Gao, Z., Henig, O., Kehoe, V., Sinoway, L.I., Li, J. J. Appl. Physiol. (2006)
- Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia. Yagi, J., Wenk, H.N., Naves, L.A., McCleskey, E.W. Circ. Res. (2006)
- Acid-induced pain and its modulation in humans. Jones, N.G., Slater, R., Cadiou, H., McNaughton, P., McMahon, S.B. J. Neurosci. (2004)
- Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter. Xia, J., Zhou, Z.H., Bubien, J.K., Fuller, C.M., Markert, J.M., Mapstone, T.B., Yancey Gillespie, G., Benos, D.J. Gene (2003)
- Modulation of Acid-sensing Ion Channel Currents, Acid-induced Increase of Intracellular Ca2+, and Acidosis-mediated Neuronal Injury by Intracellular pH. Wang, W.Z., Chu, X.P., Li, M.H., Seeds, J., Simon, R.P., Xiong, Z.G. J. Biol. Chem. (2006)
- An ASIC design for versatile receive front-end electronics of an ultrasonic medical imaging system--16 channel analog inputs and 4 dynamically focused beam outputs. Park, S.B., Kwak, J., Lee, K. Ultrasonic imaging. (2003)