Gene Review:
PTK7 - protein tyrosine kinase 7 (inactive)
Homo sapiens
Synonyms:
CCK-4, CCK4, Colon carcinoma kinase 4, Inactive tyrosine-protein kinase 7, Protein-tyrosine kinase 7, ...
Schruers,
Pols,
Overbeek,
Griez,
Raedler,
Jahn,
Goedeken,
Gescher,
Kellner,
Wiedemann,
Radu,
Ahlin,
Svanborg,
Lindefors,
Kennedy,
Bradwejn,
Koszycki,
King,
Crowe,
Vincent,
Fourie,
Banga,
Ozer,
Park,
Lee,
Akiyoshi,
Yamauchi,
Furuta,
Katsuragi,
Kohno,
Yamamoto,
Miyamoto,
Tsutsumi,
Isogawa,
Fujii,
Beinfeld,
Shlik,
Koszycki,
Bradwejn,
Katzman,
Duffin,
Shlik,
Bradwejn,
Oliva,
Llabr??s,
Fari??a,
- Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG. Park, S.K., Lee, H.S., Lee, S.T. J. Biochem. (1996)
- Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma. Easty, D.J., Mitchell, P.J., Patel, K., Flørenes, V.A., Spritz, R.A., Bennett, D.C. Int. J. Cancer (1997)
- The ventilatory response to cholecystokinin tetrapeptide in healthy volunteers. Katzman, M.A., Duffin, J., Shlik, J., Bradwejn, J. Neuropsychopharmacology (2002)
- Cholecystokinin peptides in cerebrospinal fluid: a study in healthy male subjects. Gunnarsson, T., Eklundh, T., Eriksson, M., Qureshi, G.A., Sjöberg, S., Nordin, C. Regul. Pept. (1997)
- The panicogenic effects of cholecystokinin-tetrapeptide are antagonized by L-365,260, a central cholecystokinin receptor antagonist, in patients with panic disorder. Bradwejn, J., Koszycki, D., Couëtoux du Tertre, A., van Megen, H., den Boer, J., Westenberg, H. Arch. Gen. Psychiatry (1994)
- Decrease in short-term memory function induced by CCK-4 in healthy volunteers. Shlik, J., Koszycki, D., Bradwejn, J. Peptides (1998)
- Relationship between SCL-90, Maudsley Personality Inventory and CCK4-induced intracellular calcium response in T cells. Akiyoshi, J., Yamauchi, C., Furuta, M., Katsuragi, S., Kohno, Y., Yamamoto, Y., Miyamoto, M., Tsutsumi, T., Isogawa, K., Fujii, I. Psychiatry research. (1998)
- Effects of CCK-tetrapeptide in patients with social phobia and obsessive-compulsive disorder. Katzman, M.A., Koszycki, D., Bradwejn, J. Depression and anxiety. (2004)
- Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver. Ismair, M.G., Stieger, B., Cattori, V., Hagenbuch, B., Fried, M., Meier, P.J., Kullak-Ublick, G.A. Gastroenterology (2001)
- Effect of the selective serotonin reuptake inhibitor fluvoxamine on CCK-4 induced panic attacks. van Megen, H.J., Westenberg, H.G., den Boer, J.A., Slaap, B., Scheepmakers, A. Psychopharmacology (Berl.) (1997)
- Megestrol attenuates the hormonal response to CCK-4-induced panic attacks. Raedler, T.J., Jahn, H., Goedeken, B., Gescher, D.M., Kellner, M., Wiedemann, K. Depression and anxiety. (2006)
- Assignment of PTK7 encoding a receptor protein tyrosine kinase-like molecule to human chromosome 6p21.1-->p12.2 by fluorescence in situ hybridization. Banga, S.S., Ozer, H.L., Park, S.K., Lee, S.T. Cytogenet. Cell Genet. (1997)
- Organization of the human PTK7 gene encoding a receptor protein tyrosine kinase-like molecule and alternative splicing of its mRNA. Jung, J.W., Ji, A.R., Lee, J., Kim, U.J., Lee, S.T. Biochim. Biophys. Acta (2002)
- Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family. Mossie, K., Jallal, B., Alves, F., Sures, I., Plowman, G.D., Ullrich, A. Oncogene (1995)
- CCK-4-induced calcium mobilization in T cells is enhanced in panic disorder. Akiyoshi, J., Moriyama, T., Isogawa, K., Miyamoto, M., Sasaki, I., Kuga, K., Yamamoto, H., Yamada, K., Fujii, I. J. Neurochem. (1996)
- Anxiogenic effects of the CCK(B) agonist pentagastrin in humans and dose-dependent increase in plasma C-peptide levels. Radu, D., Ahlin, A., Svanborg, P., Lindefors, N. Psychopharmacology (Berl.) (2002)
- Effect of the C-terminal tetrapeptide amide of gastrin (CCK-4) and pancreatic polypeptide on gastrointestinal electrical activity in the conscious miniature pig. Wechsung, E., Houvenaghel, A. Peptides (1996)
- The GxxxG-containing transmembrane domain of the CCK4 oncogene does not encode preferential self-interactions. Kobus, F.J., Fleming, K.G. Biochemistry (2005)
- On the biologically active structures of cholecystokinin, little gastrin, and enkephalin in the gastrointestinal system. Pincus, M.R., Carty, R.P., Chen, J., Lubowsky, J., Avitable, M., Shah, D., Scheraga, H.A., Murphy, R.B. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Pentagastrin infusions in patients with panic disorder. I. Symptoms and cardiovascular responses. Abelson, J.L., Nesse, R.M. Biol. Psychiatry (1994)
- Effect of acute tryptophan depletion on behavioral, cardiovascular, and hormonal sensitivity to cholecystokinin-tetrapeptide challenge in healthy volunteers. Koszycki, D., Zacharko, R.M., Le Melledo, J.M., Young, S.N., Bradwejn, J. Biol. Psychiatry (1996)
- Increased ACTH concentrations associated with cholecystokinin tetrapeptide-induced panic attacks in patients with panic disorder. Ströhle, A., Holsboer, F., Rupprecht, R. Neuropsychopharmacology (2000)
- An introduction to neuronal cholecystokinin. Beinfeld, M.C. Peptides (2001)
- Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization. Gorringe, K.L., Boussioutas, A., Bowtell, D.D. Genes Chromosomes Cancer (2005)
- Investigation of cholecystokinin system genes in panic disorder. Kennedy, J.L., Bradwejn, J., Koszycki, D., King, N., Crowe, R., Vincent, J., Fourie, O. Mol. Psychiatry (1999)
- The role of CCK caerulein, and CCK antagonists in nociception. Baber, N.S., Dourish, C.T., Hill, D.R. Pain (1989)
- Data analysis of kinetic modelling used in drug stability studies: isothermal versus nonisothermal assays. Oliva, A., Llabr??s, M., Fari??a, J.B. Pharm. Res. (2006)
- 10 microg CCK-4 premedication and 35% CO2 challenge in healthy volunteers. Schruers, K., Pols, H., Overbeek, T., Griez, E. Prog. Neuropsychopharmacol. Biol. Psychiatry (2000)
- Effect of CCK-4 on a 35% carbon dioxide challenge in healthy volunteers. Pols, H., Griez, E., Bourin, M., Schruers, K. Prog. Neuropsychopharmacol. Biol. Psychiatry (1999)