Gene Review:
Htr6 - 5-hydroxytryptamine (serotonin) receptor 6...
Rattus norvegicus
Synonyms:
5-HT-6, 5-HT6, 5-hydroxytryptamine receptor 6, ST-B17, Serotonin receptor 6
- Molecular and behavioral effects mediated by Gs-coupled adenosine A2a, but not serotonin 5-Ht4 or 5-Ht6 receptors following antipsychotic administration. Ward, R.P., Dorsa, D.M. Neuroscience (1999)
- Antibodies and antisense oligonucleotide for probing the distribution and putative functions of central 5-HT6 receptors. Hamon, M., Doucet, E., Lefèvre, K., Miquel, M.C., Lanfumey, L., Insausti, R., Frechilla, D., Del Rio, J., Vergé, D. Neuropsychopharmacology (1999)
- Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats. Bentley, J.C., Bourson, A., Boess, F.G., Fone, K.C., Marsden, C.A., Petit, N., Sleight, A.J. Br. J. Pharmacol. (1999)
- Central distribution and function of 5-HT6 receptor subtype in the rat brain. Yoshioka, M., Matsumoto, M., Togashi, H., Mori, K., Saito, H. Life Sci. (1998)
- Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task. Perez-García, G., Meneses, A. Pharmacol. Biochem. Behav. (2005)
- Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. Shen, Y., Monsma, F.J., Metcalf, M.A., Jose, P.A., Hamblin, M.W., Sibley, D.R. J. Biol. Chem. (1993)
- The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum. Boess, F.G., Riemer, C., Bös, M., Bentley, J., Bourson, A., Sleight, A.J. Mol. Pharmacol. (1998)
- Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist. Riemer, C., Borroni, E., Levet-Trafit, B., Martin, J.R., Poli, S., Porter, R.H., Bös, M. J. Med. Chem. (2003)
- Ionotropic glutamate receptor modulation of 5-HT6 and 5-HT7 mRNA expression in rat brain. Healy, D.J., Meador-Woodruff, J.H. Neuropsychopharmacology (1999)
- Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Kohen, R., Metcalf, M.A., Khan, N., Druck, T., Huebner, K., Lachowicz, J.E., Meltzer, H.Y., Sibley, D.R., Roth, B.L., Hamblin, M.W. J. Neurochem. (1996)
- A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation. Ruat, M., Traiffort, E., Arrang, J.M., Tardivel-Lacombe, J., Diaz, J., Leurs, R., Schwartz, J.C. Biochem. Biophys. Res. Commun. (1993)
- Quantitative RT-PCR distribution of serotonin 5-HT6 receptor mRNA in the central nervous system of control or 5,7-dihydroxytryptamine-treated rats. Gérard, C., el Mestikawy, S., Lebrand, C., Adrien, J., Ruat, M., Traiffort, E., Hamon, M., Martres, M.P. Synapse (1996)
- Clozapine: selective labeling of sites resembling 5HT6 serotonin receptors may reflect psychoactive profile. Glatt, C.E., Snowman, A.M., Sibley, D.R., Snyder, S.H. Mol. Med. (1995)
- 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: a polymerase chain reaction study. Pierce, P.A., Xie, G.X., Levine, J.D., Peroutka, S.J. Neuroscience (1996)
- Identification of 5-hydroxytryptamine receptors positively coupled to adenylyl cyclase in rat cultured astrocytes. Hirst, W.D., Price, G.W., Rattray, M., Wilkin, G.P. Br. J. Pharmacol. (1997)
- Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells. Boess, F.G., Monsma, F.J., Carolo, C., Meyer, V., Rudler, A., Zwingelstein, C., Sleight, A.J. Neuropharmacology (1997)
- BIMG 80, a novel potential antipsychotic drug: evidence for multireceptor actions and preferential release of dopamine in prefrontal cortex. Volonté, M., Monferini, E., Cerutti, M., Fodritto, F., Borsini, F. J. Neurochem. (1997)
- Reversal of a cholinergic-induced deficit in a rodent model of recognition memory by the selective 5-HT6 receptor antagonist, Ro 04-6790. Woolley, M.L., Marsden, C.A., Sleight, A.J., Fone, K.C. Psychopharmacology (Berl.) (2003)
- Colocalization of serotonin receptor subtypes 5-HT2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum. Ward, R.P., Dorsa, D.M. J. Comp. Neurol. (1996)
- 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism. King, M.V., Sleight, A.J., Woolley, M.L., Topham, I.A., Marsden, C.A., Fone, K.C. Neuropharmacology (2004)
- Effects of clozapine and haloperidol on 5-HT6 receptor mRNA levels in rat brain. Frederick, J.A., Meador-Woodruff, J.H. Schizophr. Res. (1999)
- An assessment of the effects of serotonin 6 (5-HT6) receptor antagonists in rodent models of learning. Lindner, M.D., Hodges, D.B., Hogan, J.B., Orie, A.F., Corsa, J.A., Barten, D.M., Polson, C., Robertson, B.J., Guss, V.L., Gillman, K.W., Starrett, J.E., Gribkoff, V.K. J. Pharmacol. Exp. Ther. (2003)
- Impact of adrenalectomy on 5-HT6 and 5-HT7 receptor gene expression in the rat hippocampus. Yau, J.L., Noble, J., Widdowson, J., Seckl, J.R. Brain Res. Mol. Brain Res. (1997)