Gene Review:
SLC1A6 - solute carrier family 1 (high affinity...
Homo sapiens
Synonyms:
EAAT4, Excitatory amino acid transporter 4, Sodium-dependent glutamate/aspartate transporter, Solute carrier family 1 member 6
- Glutamate transporters in neonatal cerebellar subarachnoid hemorrhage. Inage, Y.W., Itoh, M., Wada, K., Hoshika, A., Takashima, S. Pediatric neurology. (2000)
- Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus. Welsh, J.P., Yuen, G., Placantonakis, D.G., Vu, T.Q., Haiss, F., O'Hearn, E., Molliver, M.E., Aicher, S.A. Advances in neurology. (2002)
- Glutamate transporters GLAST and EAAT4 regulate postischemic Purkinje cell death: an in vivo study using a cardiac arrest model in mice lacking GLAST or EAAT4. Yamashita, A., Makita, K., Kuroiwa, T., Tanaka, K. Neurosci. Res. (2006)
- Spectrin mutations cause spinocerebellar ataxia type 5. Ikeda, Y., Dick, K.A., Weatherspoon, M.R., Gincel, D., Armbrust, K.R., Dalton, J.C., Stevanin, G., Dürr, A., Zühlke, C., Bürk, K., Clark, H.B., Brice, A., Rothstein, J.D., Schut, L.J., Day, J.W., Ranum, L.P. Nat. Genet. (2006)
- Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Jackson, M., Song, W., Liu, M.Y., Jin, L., Dykes-Hoberg, M., Lin, C.I., Bowers, W.J., Federoff, H.J., Sternweis, P.C., Rothstein, J.D. Nature (2001)
- An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Fairman, W.A., Vandenberg, R.J., Arriza, J.L., Kavanaugh, M.P., Amara, S.G. Nature (1995)
- Neuronal glutamate transporters control activation of postsynaptic metabotropic glutamate receptors and influence cerebellar long-term depression. Brasnjo, G., Otis, T.S. Neuron. (2001)
- Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity. Wadiche, J.I., Jahr, C.E. Nat. Neurosci. (2005)
- A dynamic switch between inhibitory and excitatory currents in a neuronal glutamate transporter. Melzer, N., Torres-Salazar, D., Fahlke, C. Proc. Natl. Acad. Sci. U.S.A. (2005)
- The glutamate transporter subtypes EAAT4 and EAATs 1-3 transport glutamate with dramatically different kinetics and voltage dependence but share a common uptake mechanism. Mim, C., Balani, P., Rauen, T., Grewer, C. J. Gen. Physiol. (2005)
- Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors. Pignataro, L., Sitaramayya, A., Finnemann, S.C., Sarthy, V.P. Mol. Cell. Neurosci. (2005)
- Expression of glutamate transporter subtypes in cultured retinal pigment epithelial and retinoblastoma cells. Mäenpää, H., Gegelashvili, G., Tähti, H. Curr. Eye Res. (2004)
- Facilitated activation of metabotropic glutamate receptors in cerebellar Purkinje cells in glutamate transporter EAAT4-deficient mice. Nikkuni, O., Takayasu, Y., Iino, M., Tanaka, K., Ozawa, S. Neurosci. Res. (2007)
- Differential roles of glial and neuronal glutamate transporters in Purkinje cell synapses. Takayasu, Y., Iino, M., Kakegawa, W., Maeno, H., Watase, K., Wada, K., Yanagihara, D., Miyazaki, T., Komine, O., Watanabe, M., Tanaka, K., Ozawa, S. J. Neurosci. (2005)
- Expression of two glutamate transporters, GLAST and EAAT4, in the human cerebellum: their correlation in development and neonatal hypoxic-ischemic damage. Inage, Y.W., Itoh, M., Wada, K., Takashima, S. J. Neuropathol. Exp. Neurol. (1998)
- Niflumic acid modulates uncoupled substrate-gated conductances in the human glutamate transporter EAAT4. Poulsen, M.V., Vandenberg, R.J. J. Physiol. (Lond.) (2001)
- Zn(2+) inhibits the anion conductance of the glutamate transporter EEAT4. Mitrovic, A.D., Plesko, F., Vandenberg, R.J. J. Biol. Chem. (2001)
- Coexistence and function of different neurotransmitter transporters in the plasma membrane of CNS neurons. Raiteri, L., Raiteri, M., Bonanno, G. Prog. Neurobiol. (2002)
- Striatal excitatory amino acid transporter transcript expression in schizophrenia, bipolar disorder, and major depressive disorder. McCullumsmith, R.E., Meador-Woodruff, J.H. Neuropsychopharmacology (2002)
- Neuronal glutamate transporter EAAT4 is expressed in astrocytes. Hu, W.H., Walters, W.M., Xia, X.M., Karmally, S.A., Bethea, J.R. Glia (2003)