Gene Review:
USF2 - upstream transcription factor 2, c-fos...
Homo sapiens
Synonyms:
BHLHB12, Class B basic helix-loop-helix protein 12, FIP, FOS-interacting protein, Major late transcription factor 2, ...
- The IGF2 receptor is a USF2-specific target in nontumorigenic mammary epithelial cells but not in breast cancer cells. Szentirmay, M.N., Yang, H.X., Pawar, S.A., Vinson, C., Sawadogo, M. J. Biol. Chem. (2003)
- USF/c-Myc enhances, while Yin-Yang 1 suppresses, the promoter activity of CXCR4, a coreceptor for HIV-1 entry. Moriuchi, M., Moriuchi, H., Margolis, D.M., Fauci, A.S. J. Immunol. (1999)
- Down-regulation of the polymeric immunoglobulin receptor in non-small cell lung carcinoma: correlation with dysregulated expression of the transcription factors USF and AP2. Khattar, N.H., Lele, S.M., Kaetzel, C.S. J. Biomed. Sci. (2005)
- Isolation of a novel USF2 isoform: repressor of cathepsin B expression. Yan, S., Sloane, B.F. Gene (2004)
- Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains. Luo, X., Sawadogo, M. Mol. Cell. Biol. (1996)
- Genetic association between USF 1 and USF 2 gene polymorphisms and Japanese Alzheimer's disease. Shibata, N., Ohnuma, T., Higashi, S., Higashi, M., Usui, C., Ohkubo, T., Watanabe, T., Kawashima, R., Kitajima, A., Ueki, A., Nagao, M., Arai, H. J. Gerontol. A Biol. Sci. Med. Sci. (2006)
- Antiproliferative properties of the USF family of helix-loop-helix transcription factors. Luo, X., Sawadogo, M. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Upstream stimulatory factor regulates major histocompatibility complex class I gene expression: the U2DeltaE4 splice variant abrogates E-box activity. Howcroft, T.K., Murphy, C., Weissman, J.D., Huber, S.J., Sawadogo, M., Singer, D.S. Mol. Cell. Biol. (1999)
- Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation. Qyang, Y., Luo, X., Lu, T., Ismail, P.M., Krylov, D., Vinson, C., Sawadogo, M. Mol. Cell. Biol. (1999)
- Roles for USF-2 in lung cancer proliferation and bronchial carcinogenesis. Ocejo-Garcia, M., Baokbah, T.A., Ashurst, H.L., Cowlishaw, D., Soomro, I., Coulson, J.M., Woll, P.J. J. Pathol. (2005)
- TFII-I regulates induction of chromosomally integrated human immunodeficiency virus type 1 long terminal repeat in cooperation with USF. Chen, J., Malcolm, T., Estable, M.C., Roeder, R.G., Sadowski, I. J. Virol. (2005)
- Structure, sequence, and chromosomal location of the gene for USF2 transcription factors in mouse. Henrion, A.A., Martinez, A., Mattei, M.G., Kahn, A., Raymondjean, M. Genomics (1995)
- Archaic structure of the gene encoding transcription factor USF. Lin, Q., Luo, X., Sawadogo, M. J. Biol. Chem. (1994)
- Variant forms of upstream stimulatory factors (USFs) control the promoter activity of hTERT, the human gene encoding the catalytic subunit of telomerase. Yago, M., Ohki, R., Hatakeyama, S., Fujita, T., Ishikawa, F. FEBS Lett. (2002)
- Cell type-dependent regulation of human DNA topoisomerase III alpha gene expression by upstream stimulatory factor 2. Han, S.Y., Kim, J.C., Suh, J.M., Chung, I.K. FEBS Lett. (2001)
- Transcription of the transforming growth factor-beta2 gene is dependent on an E-box located between an essential cAMP response element/activating transcription factor motif and the TATA box of the gene. Scholtz, B., Kingsley-Kallesen, M., Rizzino, A. J. Biol. Chem. (1996)
- Loss of USF transcriptional activity in breast cancer cell lines. Ismail, P.M., Lu, T., Sawadogo, M. Oncogene (1999)
- Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2. Wang, S., Skorczewski, J., Feng, X., Mei, L., Murphy-Ullrich, J.E. J. Biol. Chem. (2004)
- The E-box of the human glycophorin B promoter is involved in the erythroid-specific expression of the GPB gene. Camara-Clayette, V., Rahuel, C., Bertrand, O., Cartron, J.P. Biochem. Biophys. Res. Commun. (1999)
- Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway. Weigert, C., Brodbeck, K., Sawadogo, M., Häring, H.U., Schleicher, E.D. J. Biol. Chem. (2004)
- Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: Role of USF transcription factors. Van Dross, R.T., Hong, X., Essengue, S., Fischer, S.M., Pelling, J.C. Mol. Carcinog. (2007)
- Upstream stimulatory factor regulates Pdx-1 gene expression in differentiated pancreatic beta-cells. Qian, J., Kaytor, E.N., Towle, H.C., Olson, L.K. Biochem. J. (1999)
- Human papillomavirus type 16 E6 activates TERT gene transcription through induction of c-Myc and release of USF-mediated repression. McMurray, H.R., McCance, D.J. J. Virol. (2003)
- Human follicle-stimulating hormone receptor (FSH-R) promoter/enhancer activity is inhibited by transcriptional factors, from the upstream stimulating factors family, via E-box and newly identified initiator element (Inr) in FSH-R non-expressing cells. Putowski, L.T., Schillings, W.J., Lee, C.M., Reddy, E.P., Jakowicki, J.A. Gynecol. Endocrinol. (2004)
- Cell type-dependent regulation of the hypoxia-responsive plasminogen activator inhibitor-1 gene by upstream stimulatory factor-2. Dimova, E.Y., Kietzmann, T. J. Biol. Chem. (2006)
- Upstream stimulatory factor 2 activates the mammalian F1F0 ATP synthase alpha-subunit gene through an initiator element. Breen, G.A., Jordan, E.M. Gene Expr. (1998)
- Upstream stimulatory factor (USF) as a transcriptional suppressor of human telomerase reverse transcriptase (hTERT) in oral cancer cells. Chang, J.T., Yang, H.T., Wang, T.C., Cheng, A.J. Mol. Carcinog. (2005)
- Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose. Smih, F., Rouet, P., Lucas, S., Mairal, A., Sengenes, C., Lafontan, M., Vaulont, S., Casado, M., Langin, D. Diabetes (2002)
- Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms. Viollet, B., Lefrançois-Martinez, A.M., Henrion, A., Kahn, A., Raymondjean, M., Martinez, A. J. Biol. Chem. (1996)
- Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene. Bruno, M.E., West, R.B., Schneeman, T.A., Bresnick, E.H., Kaetzel, C.S. Mol. Immunol. (2004)
- Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1. Moore, M.L., Park, E.A., McMillin, J.B. J. Biol. Chem. (2003)