Gene Review:
BHLHE41 - basic helix-loop-helix family, member e41
Homo sapiens
Synonyms:
BHLHB3, Class B basic helix-loop-helix protein 3, Class E basic helix-loop-helix protein 41, DEC2, Differentially expressed in chondrocytes protein 2, ...
Mease,
Kivitz,
Burch,
Siegel,
Cohen,
Ory,
Salonen,
Rubenstein,
Sharp,
Tsuji,
Tanaka,
Sakahashi,
Ishii,
Sato,
Hirose,
Ishima,
Heidenblad,
Jonson,
Mahlamäki,
Gorunova,
Karhu,
Johansson,
Höglund,
van Gaalen,
van Aken,
Huizinga,
Schreuder,
Breedveld,
Zanelli,
van Venrooij,
Verweij,
Toes,
de Vries,
Landewé,
Boers,
Verhoeven,
Westhovens,
van de Laar,
Markusse,
van Denderen,
Westedt,
Peeters,
Dijkmans,
Jacobs,
Boonen,
van der Heijde,
van der Linden,
Yamada,
Miyamoto,
Bathon,
Fleischmann,
Van der Heijde,
Tesser,
Peloso,
Chon,
White,
- Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. Miyazaki, K., Kawamoto, T., Tanimoto, K., Nishiyama, M., Honda, H., Kato, Y. J. Biol. Chem. (2002)
- DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter. Li, Y., Xie, M., Song, X., Gragen, S., Sachdeva, K., Wan, Y., Yan, B. J. Biol. Chem. (2003)
- Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis. van Gaalen, F.A., van Aken, J., Huizinga, T.W., Schreuder, G.M., Breedveld, F.C., Zanelli, E., van Venrooij, W.J., Verweij, C.L., Toes, R.E., de Vries, R.R. Arthritis Rheum. (2004)
- Performance of an automated computer-based scoring method to assess joint space narrowing in rheumatoid arthritis: a longitudinal study. Finckh, A., de Pablo, P., Katz, J.N., Neumann, G., Lu, Y., Wolfe, F., Duryea, J. Arthritis Rheum. (2006)
- Use of the sharp and larsen scoring methods in the assessment of radiographic progression in juvenile idiopathic arthritis. Rossi, F., Di Dia, F., Galip??, O., Pistorio, A., Valle, M., Magni-Manzoni, S., Ruperto, N., Tom??, P., Martini, A., Ravelli, A. Arthritis Rheum. (2006)
- A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for rheumatoid arthritis structural severity. Gourraud, P.A., Boyer, J.F., Barnetche, T., Abbal, M., Cambon-Thomsen, A., Cantagrel, A., Constantin, A. Arthritis Rheum. (2006)
- Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Cohen, S.B., Emery, P., Greenwald, M.W., Dougados, M., Furie, R.A., Genovese, M.C., Keystone, E.C., Loveless, J.E., Burmester, G.R., Cravets, M.W., Hessey, E.W., Shaw, T., Totoritis, M.C. Arthritis Rheum. (2006)
- Etanercept treatment of psoriatic arthritis: safety, efficacy, and effect on disease progression. Mease, P.J., Kivitz, A.J., Burch, F.X., Siegel, E.L., Cohen, S.B., Ory, P., Salonen, D., Rubenstein, J., Sharp, J.T., Tsuji, W. Arthritis Rheum. (2004)
- Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Keystone, E.C., Kavanaugh, A.F., Sharp, J.T., Tannenbaum, H., Hua, Y., Teoh, L.S., Fischkoff, S.A., Chartash, E.K. Arthritis Rheum. (2004)
- Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli. Yamada, K., Miyamoto, K. Front. Biosci. (2005)
- UVB radiation induces expression of HIF-1alpha and VEGF through the EGFR/PI3K/DEC1 pathway. Li, Y., Bi, Z., Yan, B., Wan, Y. Int. J. Mol. Med. (2006)
- Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex. Sharp, K.H., Moody, P.C., Brown, K.A., Raven, E.L. Biochemistry (2004)
- Interaction of ascorbate peroxidase with substrates: a mechanistic and structural analysis. Macdonald, I.K., Badyal, S.K., Ghamsari, L., Moody, P.C., Raven, E.L. Biochemistry (2006)
- Surgical correction of residual hip dysplasia in two pediatric age-groups. Lalonde, F.D., Frick, S.L., Wenger, D.R. The Journal of bone and joint surgery. American volume. (2002)
- Anti-cyclic citrullinated peptide antibody in rheumatoid arthritis: relation with disease aggressiveness. del Val del Amo, N., Ibanez Bosch, R., Fito Manteca, C., Gutierrez Polo, R., Loza Cortina, E. Clin. Exp. Rheumatol. (2006)
- Ear drops for the removal of ear wax. Burton, M.J., Dorée, C.J. Cochrane database of systematic reviews (Online) (2003)
- Radial Artery Harvest Using the Sharp Scissors Method for Patients with Pathological Findings on Allen's Test. Hata, M., Sezai, A., Niino, T., Yoda, M., Wakui, S., Soeda, M., Nohata, I., Shiono, M., Minami, K. Surg. Today (2006)
- The basic helix-loop-helix protein, sharp-1, represses transcription by a histone deacetylase-dependent and histone deacetylase-independent mechanism. Garriga-Canut, M., Roopra, A., Buckley, N.J. J. Biol. Chem. (2001)
- COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention. Landewé, R.B., Boers, M., Verhoeven, A.C., Westhovens, R., van de Laar, M.A., Markusse, H.M., van Denderen, J.C., Westedt, M.L., Peeters, A.J., Dijkmans, B.A., Jacobs, P., Boonen, A., van der Heijde, D.M., van der Linden, S. Arthritis Rheum. (2002)
- Safety and efficacy of etanercept treatment in elderly subjects with rheumatoid arthritis. Bathon, J.M., Fleischmann, R.M., Van der Heijde, D., Tesser, J.R., Peloso, P.M., Chon, Y., White, B. J. Rheumatol. (2006)
- Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration. Oliveira, C.H., Medeiros Silva, R., Santagada, V., Caliendo, G., Perissutti, E., Prado Galuppo, M., Marcondes Rezende, V., Barrientos-Astigarraga, R.E., Duarte Mendes, G., De Nucci, G. International journal of clinical pharmacology and therapeutics. (2006)
- Stromelysin 1 (matrix metalloproteinase 3) and HLA-DRB1 gene polymorphisms: Association with severity and progression of rheumatoid arthritis in a prospective study. Constantin, A., Lauwers-Cancès, V., Navaux, F., Abbal, M., van Meerwijk, J., Mazières, B., Cambon-Thomsen, A., Cantagrel, A. Arthritis Rheum. (2002)
- Synovial membrane enhancement and bone erosion by magnetic resonance imaging for prediction of radiologic progression in patients with early rheumatoid arthritis. Tanaka, N., Sakahashi, H., Ishii, S., Sato, E., Hirose, K., Ishima, T. Rheumatol. Int. (2005)
- Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. St Clair, E.W., van der Heijde, D.M., Smolen, J.S., Maini, R.N., Bathon, J.M., Emery, P., Keystone, E., Schiff, M., Kalden, J.R., Wang, B., Dewoody, K., Weiss, R., Baker, D. Arthritis Rheum. (2004)
- Detailed genomic mapping and expression analyses of 12p amplifications in pancreatic carcinomas reveal a 3.5-Mb target region for amplification. Heidenblad, M., Jonson, T., Mahlamäki, E.H., Gorunova, L., Karhu, R., Johansson, B., Höglund, M. Genes Chromosomes Cancer (2002)
- Randomized trial on two types of thermoplastic masks for patient immobilization during radiation therapy for head-and-neck cancer: In regard to Sharp et al. (Int J Radiat Oncol Biol Phys 2005;61:250-256). Roques, T., Dagless, M., Tomes, J. Int. J. Radiat. Oncol. Biol. Phys. (2005)
- Fast oscillations trigger bursts of action potentials in neocortical neurons in vitro: A quasi-white-noise analysis study. Schindler, K.A., Goodman, P.H., Wieser, H.G., Douglas, R.J. Brain Res. (2006)
- Relative bioavailability study of 20-mg enalapril tablets in healthy male volunteers. Lohitnavy, O., Lohitnavy, M., Polnok, S., Taytiwat, P. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. (2003)