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MeSH Review


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Disease relevance of Cerumen


High impact information on Cerumen

  • In 6 subjects, the alkane content of cerumen from each ear was examined to investigate whether alkanes arrive at the skin surface by a systemic route or by direct contact with environmental surfaces [6].
  • Freshly collected cerumen (dry form) suspended at a concentration of 3% in glycerol-sodium bicarbonate buffer showed bactericidal activity against some strains of bacteria tested [7].
  • Cerumen pigment, CK7, and p63 can help to distinguish this tumor from other neoplasms that occur in the region [8].
  • Docusate sodium, triethanolamine polypeptide, and saline were compared to determine their effectiveness in relieving cerumen obstruction in children [9].
  • We compared the ceruminolytic effects of triethanolamine polypeptide and docusate sodium in patients with cerumen [10].

Biological context of Cerumen


Anatomical context of Cerumen


Associations of Cerumen with chemical compounds


Gene context of Cerumen

  • Swirls, wrinkles and the whole ball of wax (the source of keratin in cerumen) [13].
  • Studies on hexachlorocyclohexane and DDT contents in human cerumen and their relationships to cancer mortality [17].
  • Four Mongoloid populations, viz., Garo , Hajong , Rabha and Koch, belonging to the Tibetoburman language family of Garo Hills, India, were examined for blood types ( A1A2BO , Rh, MN), secretor factor, ability to taste PTC and cerumen types [18].
  • Our data indicate that the keratin antibodies stained normal epithelial structures in the head and neck except for cells with active secretory functions such as mucus, cerumen, or salivary secretion [19].
  • This retrospective study examined the pattern of medical illnesses, surgical procedures, and medication usage among 249 patients with allergic rhinitis contrasted with a comparison group of 253 patients with cerumen impaction [20].


  1. Management of the ear canal seborrhea with cerumen. Storrs, L.A. Laryngoscope (1981) [Pubmed]
  2. Microbiology of normal external auditory canal. Stroman, D.W., Roland, P.S., Dohar, J., Burt, W. Laryngoscope (2001) [Pubmed]
  3. Does cerumen have a risk for transmission of hepatitis B? Kalcioglu, M.T., Durmaz, R., Ozturan, O., Bayindir, Y., Direkel, S. Laryngoscope (2004) [Pubmed]
  4. Dermatophytosis of the ear. Morinaka, S. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. (2005) [Pubmed]
  5. Differential diagnosis and treatment of hearing loss. Isaacson, J.E., Vora, N.M. American family physician. (2003) [Pubmed]
  6. The origin of alkanes found in human skin surface lipids. Bortz, J.T., Wertz, P.W., Downing, D.T. J. Invest. Dermatol. (1989) [Pubmed]
  7. Bactericidal activity of cerumen. Chai, T.J., Chai, T.C. Antimicrob. Agents Chemother. (1980) [Pubmed]
  8. Ceruminous adenomas: a clinicopathologic study of 41 cases with a review of the literature. Thompson, L.D., Nelson, B.L., Barnes, E.L. Am. J. Surg. Pathol. (2004) [Pubmed]
  9. Randomized clinical trial of docusate, triethanolamine polypeptide, and irrigation in cerumen removal in children. Whatley, V.N., Dodds, C.L., Paul, R.I. Archives of pediatrics & adolescent medicine. (2003) [Pubmed]
  10. Ceruminolytic effects of docusate sodium: a randomized, controlled trial. Singer, A.J., Sauris, E., Viccellio, A.W. Annals of emergency medicine. (2000) [Pubmed]
  11. Population genetics and structure of Buryats from the Lake Baikal Region of Siberia. Novoradovsky, A.G., Spitsyn, V.A., Duggirala, R., Crawford, M.H. Hum. Biol. (1993) [Pubmed]
  12. Ceruminolytic efficacy in adults versus children. Carr, M.M., Smith, R.L. The Journal of otolaryngology. (2001) [Pubmed]
  13. Swirls, wrinkles and the whole ball of wax (the source of keratin in cerumen). Naiberg, J.B., Robinson, A., Kwok, P., Hawke, M. The Journal of otolaryngology. (1992) [Pubmed]
  14. Composition of cerumen lipids. Bortz, J.T., Wertz, P.W., Downing, D.T. J. Am. Acad. Dermatol. (1990) [Pubmed]
  15. Characterization of 2,7-anhydro-N-acetylneuraminic acid in human wet cerumen. Suzuki, M., Suzuki, A., Yamakawa, T., Matsunaga, E. J. Biochem. (1985) [Pubmed]
  16. A technique for measuring the rate of cerumen production. Cipriani, C., Taborelli, G., Cardo, P.P., Rebora, A. Laryngoscope (1986) [Pubmed]
  17. Studies on hexachlorocyclohexane and DDT contents in human cerumen and their relationships to cancer mortality. Wang, X.Q., Gao, P.Y., Lin, Y.Z., Chen, C.M. Biomed. Environ. Sci. (1988) [Pubmed]
  18. A genetic survey in four Mongoloid populations of the Garo Hills, India. Deka, R. Anthropologischer Anzeiger; Bericht über die biologisch-anthropologische Literatur. (1984) [Pubmed]
  19. Immunohistochemical localization of keratin in head and neck neoplasms and normal tissues. Shi, S.R., Bhan, A.K., Pilch, B.Z., Chen, L.B., Goodman, M.L. The Journal of otolaryngology. (1985) [Pubmed]
  20. Allergic disease and associated concurrent medical illnesses. Krouse, J.H., Krouse, H.J. ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses. (2002) [Pubmed]
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