Gene Review:
CDC45 - Cdc45p
Saccharomyces cerevisiae S288c
Synonyms:
Cell division control protein 45, L8004.11, SLD4, YLR103C
- Requirement of CDC45 for postimplantation mouse development. Yoshida, K., Kuo, F., George, E.L., Sharpe, A.H., Dutta, A. Mol. Cell. Biol. (2001)
- A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. Pacek, M., Walter, J.C. EMBO J. (2004)
- Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Aparicio, O.M., Weinstein, D.M., Bell, S.P. Cell (1997)
- Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Zou, L., Stillman, B. Science (1998)
- GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Takayama, Y., Kamimura, Y., Okawa, M., Muramatsu, S., Sugino, A., Araki, H. Genes Dev. (2003)
- A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication. Kubota, Y., Takase, Y., Komori, Y., Hashimoto, Y., Arata, T., Kamimura, Y., Araki, H., Takisawa, H. Genes Dev. (2003)
- CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication. Owens, J.C., Detweiler, C.S., Li, J.J. Proc. Natl. Acad. Sci. U.S.A. (1997)
- CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication. Zou, L., Mitchell, J., Stillman, B. Mol. Cell. Biol. (1997)
- A role for the replication proteins PCNA, RF-C, polymerase epsilon and Cdc45 in transcriptional silencing in Saccharomyces cerevisiae. Ehrenhofer-Murray, A.E., Kamakaka, R.T., Rine, J. Genetics (1999)
- Identification of Cdc45p, an essential factor required for DNA replication. Hardy, C.F. Gene (1997)
- Human CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase alpha. Kukimoto, I., Igaki, H., Kanda, T. Eur. J. Biochem. (1999)
- Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification. Loebel, D., Huikeshoven, H., Cotterill, S. Nucleic Acids Res. (2000)
- The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts. Shikata, K., Sasa-Masuda, T., Okuno, Y., Waga, S., Sugino, A. BMC Biochem. (2006)
- Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication. Hopwood, B., Dalton, S. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: identification of Cdc45p as a subunit. Dalton, S., Hopwood, B. Mol. Cell. Biol. (1997)
- Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Araki, Y., Kawasaki, Y., Sasanuma, H., Tye, B.K., Sugino, A. Genes Cells (2003)
- Histone acetylation regulates the time of replication origin firing. Vogelauer, M., Rubbi, L., Lucas, I., Brewer, B.J., Grunstein, M. Mol. Cell (2002)
- Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Zou, L., Stillman, B. Mol. Cell. Biol. (2000)
- Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding. Gregan, J., Lindner, K., Brimage, L., Franklin, R., Namdar, M., Hart, E.A., Aves, S.J., Kearsey, S.E. Mol. Biol. Cell (2003)
- CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast. Tanaka, S., Umemori, T., Hirai, K., Muramatsu, S., Kamimura, Y., Araki, H. Nature (2007)
- Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae. Kamimura, Y., Tak, Y.S., Sugino, A., Araki, H. EMBO J. (2001)