Disease relevance of Thoracostomy

• In this prospective, randomized comparison of two well-established pleurodesis procedures, 36 patients with malignant pleural effusions, expanded lungs after drainage, and expected survival of > 1 mo received either bleomycin instillation (60E) via a small-bore thoracostomy tube or thoracoscopic talc poudrage (5 g) under local anesthesia [1].
• METHODS: Twenty-seven patients with congenital scoliosis associated with fused ribs of the concave hemithorax had an opening wedge thoracostomy with primary longitudinal lengthening with use of a chest-wall distractor known as a vertical, expandable prosthetic titanium rib [2].
• We used intrapleural instillation of quinacrine hydrochloride in 20 patients (Group A) with recurrent spontaneous pneumothorax (one bilateral) and compared their clinical course with 19 patients who underwent thoracotomy and scarification or pleurectomy (Group B) and 63 patients treated by tube thoracostomy alone (Group C) [3].
• Therapy of empyema associated with C. sordelli should consist of tube thoracostomy as well as penicillin with or without metronidazole or the combination of vancomycin and metronidazole in penicillin-allergic patients [4].

High impact information on Thoracostomy

• A pleural fluid pH below 7.00 and/or a glucose level below 40 mg/100 ml are indications for immediate tube thoracostomy [5].
• CONCLUSION: Intrapleural fibrinolysis with urokinase or alteplase facilitates thoracostomy tube drainage of parapneumonic pleural fluid [6].
• Efficacy of short term versus long term tube thoracostomy drainage before tetracycline pleurodesis in the treatment of malignant pleural effusions [7].
• We describe herein a minimally invasive and inexpensive technique using fluorescein dye that can confirm the persistence of esophageal leak drained by tube thoracostomy without requiring expensive and potentially morbid invasive or radiological techniques [8].
• After operation, minocycline hydrochloride, 7 mg/kg, was instilled into the pleural space through a thoracostomy tube [9].

Chemical compound and disease context of Thoracostomy

• BACKGROUND: The purpose of this study was to compare the effectiveness and safety of a chronic indwelling pleural catheter with doxycycline pleurodesis via tube thoracostomy in the treatment of patients with recurrent symptomatic malignant pleural effusions (MPE) [10].

Associations of Thoracostomy with chemical compounds

• Patients in group 1 had tube thoracostomy suction drainage until radiological evidence of lung re-expansion was obtained and the amount of fluid drained was < 150 ml/day, before tetracycline (1.5 g) was instilled [7].
• Approximately 30%-40% of any administered dose of bupivacaine was lost via the thoracostomy tube over a 4-h period [11].
• The results on the nitroblue tetrazolium test did not help to identify those patients with pneumonia who eventually required tube thoracostomy [12].
• Open thoracotomy with pleural abrasion is compared to observation, tube thoracostomy, and tube thoracostomy with instillation of quinacrine [13].
• Evenly spaced radiopaque markings on thoracostomy tubes would facilitate recognition of fissure placement, which can sometimes result in inadequate drainage [14].

Gene context of Thoracostomy

• The objective of this study was to evaluate the effectiveness and safety of intrapleural tissue plasminogen activator (tPA) in children who require tube thoracostomy for drainage of a complicated parapneumonic effusion [15].
• CONCLUSIONS: Tube thoracostomy can be safely performed by pulmonologists with relatively few associated problems [16].
• CONCLUSION: Image-guided drainage with adjunctive pleural urokinase therapy is a safe and effective method of closed thoracostomy drainage of complicated pleural fluid collections and can obviate surgery in most cases [17].
• The authors report 2 cases of tumor recurrence at thoracostomy tube insertion sites after intraoperative gross spillage of pleuropulmonary blastoma and malignant epithelial thymoma and discuss approaches that may potentially prevent this devastating complication [18].

Analytical, diagnostic and therapeutic context of Thoracostomy

• BACKGROUND--A study was undertaken to compare the efficacy of short term tube thoracostomy drainage with standard tube thoracostomy drainage before instillation of tetracycline for sclerotherapy of malignant pleural effusions [7].
• The Renografin was infused by either a peritoneal lavage or thoracostomy catheter [19].
• Responses to steroid and chest tube thoracostomy were excellent [20].
• Management of the baby consisted of ventilatory support in the delivery room, repeated thoracentesis and thoracostomy tube drainage, total parenteral nutrition and formula containing medium-chain triglycerides [21].

References