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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Proctocolitis


High impact information on Proctocolitis


Chemical compound and disease context of Proctocolitis


Anatomical context of Proctocolitis

  • Prior to receiving supplementation, patients with proctocolitis (n = 18) showed significantly higher numbers of cells expressing CD3 (pan T cells) and HLA-DR and IgM containing cells compared with non-colitic controls (n = 8) [13].
  • Methylene Blue dye spraying method is currently used in the endoscopic assessment of the colonic mucosa of patients with chronic ulcerative proctocolitis [14].
  • The influence of intermittent colorectal distension (CRD) on proximal colonic motility and abdominal pain perception was investigated in awake rats equipped with intraparietal electrodes on the cecum, proximal colon, and abdomen, before and three days after rectocolitis induction by trinitrobenzene sulfonic acid (TNB)/ethanol [15].

Gene context of Proctocolitis


Analytical, diagnostic and therapeutic context of Proctocolitis


  1. 5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis. Sutherland, L.R., Martin, F., Greer, S., Robinson, M., Greenberger, N., Saibil, F., Martin, T., Sparr, J., Prokipchuk, E., Borgen, L. Gastroenterology (1987) [Pubmed]
  2. Isotretinoin-associated proctosigmoiditis. Martin, P., Manley, P.N., Depew, W.T., Blakeman, J.M. Gastroenterology (1987) [Pubmed]
  3. Comparison of mesalazine suppositories in proctitis and distal proctosigmoiditis. Gionchetti, P., Rizzello, F., Venturi, A., Brignola, C., Ferretti, M., Peruzzo, S., Campieri, M. Aliment. Pharmacol. Ther. (1997) [Pubmed]
  4. Increased frequency of HLA-DR3 and complotype SCO1 in Mexican mestizo children with amoebic abscess of the liver. Arellano, J., Peŕez-Rodríguez, M., López-Osuna, M., Velázquez, J.R., Granados, J., Justiniani, N., Santos, J.I., Madrazo, A., Muñoz, L., Kretschmer, R. Parasite Immunol. (1996) [Pubmed]
  5. Influence of trimebutine on inflammation- and stress-induced hyperalgesia to rectal distension in rats. Lacheze, C., Coelho, A.M., Fioramonti, J., Buéno, L. J. Pharm. Pharmacol. (1998) [Pubmed]
  6. Treatment of chronic proctosigmoiditis with cyclosporin enemas. Ranzi, T., Campanini, M.C., Velio, P., Quarto di Palo, F., Bianchi, P. Lancet (1989) [Pubmed]
  7. Calcipotriol inhibits rectal epithelial cell proliferation in ulcerative proctocolitis. Thomas, M.G., Nugent, K.P., Forbes, A., Williamson, R.C. Gut (1994) [Pubmed]
  8. Plasma prednisolone levels and adrenocortical responsiveness after administration of prednisolone-21-phosphate as a retention enema. Lee, D.A., Taylor, G.M., James, V.H., Walker, G. Gut (1979) [Pubmed]
  9. Treatment of distal ulcerative colitis (proctosigmoiditis) in relapse: comparison of hydrocortisone enemas and rectal hydrocortisone foam. Ruddell, W.S., Dickinson, R.J., Dixon, M.F., Axon, A.T. Gut (1980) [Pubmed]
  10. Topical salicylate therapy (4-ASA and 5-ASA enemas). Ginsberg, A.L. Gastroenterol. Clin. North Am. (1989) [Pubmed]
  11. Colonic motility in chronic ulcerative proctosigmoiditis and the effects of nicotine on colonic motility in patients and healthy subjects. Coulie, B., Camilleri, M., Bharucha, A.E., Sandborn, W.J., Burton, D. Aliment. Pharmacol. Ther. (2001) [Pubmed]
  12. Effect of ecabet sodium enema on mildly to moderately active ulcerative proctosigmoiditis: an open-label study. Kono, T., Nomura, M., Kasai, S., Kohgo, Y. Am. J. Gastroenterol. (2001) [Pubmed]
  13. Distal proctocolitis and n-3 polyunsaturated fatty acids (n-3 PUFAs): the mucosal effect in situ. Almallah, Y.Z., Ewen, S.W., El-Tahir, A., Mowat, N.A., Brunt, P.W., Sinclair, T.S., Heys, S.D., Eremin, O. J. Clin. Immunol. (2000) [Pubmed]
  14. Methylene blue dye spraying method in patients with ulcerative proctitis: a comparative study with morphological findings and functional capacity of the rectal epithelium. Baldi, F., di Febo, G., Biasco, G., Gizzi, G., Ferrarini, F., Milazzo, G., Barbara, L. Endoscopy. (1979) [Pubmed]
  15. Experimental colitis alters visceromotor response to colorectal distension in awake rats. Morteau, O., Hachet, T., Caussette, M., Bueno, L. Dig. Dis. Sci. (1994) [Pubmed]
  16. Carcinoembryonic antigen in patients suffering from ulcerative proctocolitis. Mitchell, A.B., Gill, A.M., Orchard, R.T., Parkins, R.A. The American journal of digestive diseases. (1975) [Pubmed]
  17. A controlled comparison of corticotropin and hydrocortisone in the treatment of severe proctocolitis. Powell-Tuck, J., Buckell, N.A., Lennard-Jones, J.E. Scand. J. Gastroenterol. (1977) [Pubmed]
  18. Influence of 5-HT3 receptor antagonists in visceromotor and nociceptive responses to rectal distension before and during experimental colitis in rats. Morteau, O., Julia, V., Eeckhout, C., Bueno, L. Fundamental & clinical pharmacology. (1994) [Pubmed]
  19. Outbreak of glutaraldehyde-induced proctocolitis. Dolcé, P., Gourdeau, M., April, N., Bernard, P.M. American journal of infection control. (1995) [Pubmed]
  20. Mesalazine (5-aminosalicylic acid) suppositories in the treatment of ulcerative proctitis or distal proctosigmoiditis. A randomized controlled trial. Campieri, M., De Franchis, R., Bianchi Porro, G., Ranzi, T., Brunetti, G., Barbara, L. Scand. J. Gastroenterol. (1990) [Pubmed]
  21. Epidemiology of proctocolitis in the region of Leiden, The Netherlands. A population study from 1979 to 1983. Shivananda, S., Peña, A.S., Mayberry, J.F., Ruitenberg, E.J., Hoedemaeker, P.J. Scand. J. Gastroenterol. (1987) [Pubmed]
  22. Mesalamine in ulcerative colitis. Fitzgerald, J.M., Marsh, T.D. DICP : the annals of pharmacotherapy. (1991) [Pubmed]
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