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MeSH Review


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Disease relevance of Proctitis


High impact information on Proctitis


Chemical compound and disease context of Proctitis


Biological context of Proctitis


Anatomical context of Proctitis

  • The present study was performed to evaluate human neutrophil lipocalin (HNL) as a specific neutrophil marker in the inflamed lesions of the colon and rectum in patients with colitis and proctitis [16].
  • All five patients infected with serovar L-1 were homosexual men who had symptomatic proctitis characterized by rectal pain, discharge, tenesmus, abnormalities seen on anoscopy, and leukocytes seen on gram stains of rectal specimens [17].
  • Lymphoid follicular proctitis was, overall, characterized by rectal bleeding, a congested and granular mucosa without ulceration, abnormal and coalescing hyperplastic lymphoid follicles without acute inflammation, and failure to respond to local steroid therapy [18].
  • Our results indicate that methylene blue dye spraying method can be useful in the functional assessment of the rectal epithelium, especially for differentiating normal subjects and patients with mild ulcerative proctitis [19].
  • Oral administration of cyclosporin does not prevent expansion of antigen-specific, gut-associated, and spleen lymphocyte populations during Chlamydia trachomatis proctitis in nonhuman primates [20].

Gene context of Proctitis


Analytical, diagnostic and therapeutic context of Proctitis


  1. Oral acyclovir for treatment of first-episode herpes simplex virus proctitis. Rompalo, A.M., Mertz, G.J., Davis, L.G., Benedetti, J., Critchlow, C., Stamm, W.E., Corey, L. JAMA (1988) [Pubmed]
  2. Persistence of proctitis in 2 cases of clindamycin-associated colitis. Goodacre, R.L., Hamilton, J.D., Mullens, J.E., Qizilbash, A. Gastroenterology (1977) [Pubmed]
  3. Custom-made capsules and suppositories of methadone for patients on high-dose opioids for cancer pain. Bruera, E., Watanabe, S., Fainsinger, R.L., Spachynski, K., Suarez-Almazor, M., Inturrisi, C. Pain (1995) [Pubmed]
  4. 5-Aminosalicylic acid suppositories in the maintenance of remission in idiopathic proctitis or proctosigmoiditis: a double-blind placebo-controlled clinical trial. D'Arienzo, A., Panarese, A., D'Armiento, F.P., Lancia, C., Quattrone, P., Giannattasio, F., Boscaino, A., Mazzacca, G. Am. J. Gastroenterol. (1990) [Pubmed]
  5. Formalin therapy for radiation proctitis. Isenberg, G.A., Goldstein, S.D., Resnik, A.M. JAMA (1994) [Pubmed]
  6. The treatment of gonococcal proctitis. An evaluation of 173 patients treated with 4 g of spectinomycin. Fiumara, N.J. JAMA (1978) [Pubmed]
  7. Rectal sucralfate in radiation proctitis. Kochhar, R., Sharma, S.C., Gupta, B.B., Mehta, S.K. Lancet (1988) [Pubmed]
  8. Lignocaine and ulcerative proctitis. Björck, S., Ahlman, H., Dahlström, A. Lancet (1988) [Pubmed]
  9. Severe radiation-induced proctitis treated with botulinum anatoxin type A. De Micheli, C., Fornengo, P., Bosio, A., Epifani, G., Pascale, C. J. Clin. Oncol. (2003) [Pubmed]
  10. Use of mesalazine slow release suppositories 1 g three times per week to maintain remission of ulcerative proctitis: a randomised double blind placebo controlled multicentre study. Marteau, P., Crand, J., Foucault, M., Rambaud, J.C. Gut (1998) [Pubmed]
  11. Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine. van Hees, P.A., Bakker, J.H., van Tongeren, J.H. Gut (1980) [Pubmed]
  12. Disodium cromoglycate in the treatment of chronic proctitis. Heatley, R.V., Calcraft, B.J., Rhodes, J., Owen, E., Evans, B.K. Gut (1975) [Pubmed]
  13. Metronidazole in the treatment of chronic proctitis: a controlled trial. Davies, P.S., Rhodes, J., Heatley, R.V., Owen, E. Gut (1977) [Pubmed]
  14. Therapeutic regimens for anorectal gonococcal infection in males. Klein, E.J., Fisher, L.S., Chow, A.W., Guze, L.B. Arch. Intern. Med. (1977) [Pubmed]
  15. A pathophysiologic study of diversion proctitis. Winslet, M.C., Poxon, V., Youngs, D.J., Thompson, H., Keighley, M.R. Surgery, gynecology & obstetrics. (1993) [Pubmed]
  16. Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis. Carlson, M., Raab, Y., Sevéus, L., Xu, S., Hällgren, R., Venge, P. Gut (2002) [Pubmed]
  17. Infection with Chlamydia trachomatis lymphogranuloma venereum serovar L1 in homosexual men with proctitis: molecular analysis of an unusual case cluster. Bauwens, J.E., Lampe, M.F., Suchland, R.J., Wong, K., Stamm, W.E. Clin. Infect. Dis. (1995) [Pubmed]
  18. Lymphoid follicular proctitis. A condition different from ulcerative proctitis? Fléjou, J.F., Potet, F., Bogomoletz, W.V., Rigaud, C., Fenzy, A., Le Quintrec, Y., Goldfain, D., Brousse, N. Dig. Dis. Sci. (1988) [Pubmed]
  19. Methylene blue dye spraying method in patients with ulcerative proctitis: a comparative study with morphological findings and functional capacity of the rectal epithelium. Baldi, F., di Febo, G., Biasco, G., Gizzi, G., Ferrarini, F., Milazzo, G., Barbara, L. Endoscopy. (1979) [Pubmed]
  20. Oral administration of cyclosporin does not prevent expansion of antigen-specific, gut-associated, and spleen lymphocyte populations during Chlamydia trachomatis proctitis in nonhuman primates. Zeitz, M., Quinn, T.C., Graeff, A.S., Schwarting, R., James, S.P. Dig. Dis. Sci. (1989) [Pubmed]
  21. Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases. Pierik, M., Joossens, S., Van Steen, K., Van Schuerbeek, N., Vlietinck, R., Rutgeerts, P., Vermeire, S. Inflamm. Bowel Dis. (2006) [Pubmed]
  22. Ulcerative proctitis, rectal prolapse, and intestinal pseudo-obstruction in transgenic mice overexpressing hepatocyte growth factor/scatter factor. Takayama, H., Takagi, H., Larochelle, W.J., Kapur, R.P., Merlino, G. Lab. Invest. (2001) [Pubmed]
  23. Mucosal cytokine production in radiation-induced proctosigmoiditis compared with inflammatory bowel disease. Indaram, A.V., Visvalingam, V., Locke, M., Bank, S. Am. J. Gastroenterol. (2000) [Pubmed]
  24. Mucin secretion in inflammatory bowel disease: correlation with disease activity and dysplasia. Ehsanullah, M., Filipe, M.I., Gazzard, B. Gut (1982) [Pubmed]
  25. The effect of oral sucralfate on the acute proctitis associated with prostate radiotherapy: a double-blind, randomized trial. Kneebone, A., Mameghan, H., Bolin, T., Berry, M., Turner, S., Kearsley, J., Graham, P., Fisher, R., Delaney, G. Int. J. Radiat. Oncol. Biol. Phys. (2001) [Pubmed]
  26. A phase III randomized, placebo-controlled, double-blind study of misoprostol rectal suppositories to prevent acute radiation proctitis in patients with prostate cancer. Hille, A., Schmidberger, H., Hermann, R.M., Christiansen, H., Saile, B., Pradier, O., Hess, C.F. Int. J. Radiat. Oncol. Biol. Phys. (2005) [Pubmed]
  27. Avascular necrosis of bilateral knees secondary to corticosteroid enemas. Braverman, D.L., Lachmann, E.A., Nagler, W. Archives of physical medicine and rehabilitation. (1998) [Pubmed]
  28. Sucralfate does not ameliorate acute radiation proctitis: randomised study and meta-analysis. Hovdenak, N., Sørbye, H., Dahl, O. Clinical oncology (Royal College of Radiologists (Great Britain)) (2005) [Pubmed]
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