Disease relevance of Zimbabwe

• HIV and other predictors of serum folate, serum ferritin, and hemoglobin in pregnancy: a cross-sectional study in Zimbabwe [1].
• Strains of Brucella melitensis biovars 1, 2, and 3 isolated in India, Italy, Kuwait, Saudi Arabia, the Federal Republic of Germany, and Zimbabwe were inhibited by thionin (20 micrograms/ml) but not by basic fuchsin (20 micrograms/ml) or safranin O (200 micrograms/ml) [2].
• Vitamin B12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe [3].
• Non-endemic control sera were obtained from a schistosomiasis non-endemic part of Zimbabwe and from Norwegian blood donors [4].
• Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe [5].

High impact information on Zimbabwe

• Misuse of mefloquine for malaria prophylaxis in Zimbabwe [6].
• Effect of postpartum maternal or neonatal vitamin A supplementation on infant mortality among infants born to HIV-negative mothers in Zimbabwe [7].
• In this study, DNA sequence variation was examined for a 4-kb region of the bcd gene, including a portion of the 5' UTR, the entire coding region, and the 3' UTR, for 25 Drosophila melanogaster isofemale lines from Zimbabwe and one allele from D. simulans [8].
• We tested the efficacy of various regimens for the intermittent administration of potassium iodide in Hwedza, Zimbabwe, an area of known severe iodine deficiency [9].
• The prevalence of OCA2 in schoolchildren in Harare, the capital city of Zimbabwe, was found to be 1 in 2833 [10].

Chemical compound and disease context of Zimbabwe

• Biochemical signs of hyperthyroidism, or even overt and possibly lethal clinical hyperthyroidism were reported in 2 severely iodine-deficient African countries (Zimbabwe and Democratic Republic of Congo, RDC) soon after the introduction of iodized salt [11].
• Status of chloroquine efficacy against falciparum malaria in the Mola area of Kariba district, Zimbabwe [12].
• Combining the data from various studies by fibre type, the percentage of mesotheliomas was 0.6% for Zimbabwe (Rhodesian) chrysotile, 2.5% for the various amphiboles as a group, and 4.7% for Quebec (Canadian) chrysotile [13].
• Dental caries, fluoride levels and oral hygiene practices of school children in Matebeleland South, Zimbabwe [14].
• A total of 1,286 caprine serum samples collected from three communal land areas in Zimbabwe from March 1999 to February 2000 were tested for Ehrlichia ruminantium antibodies using the indirect MAP1-B enzyme-linked immunosorbent assay [15].

Biological context of Zimbabwe

• Polymorphic acetylation of sulphamethazine in a Zimbabwe population [16].
• We measured four-cutter DNA restriction site and allozyme variation at Pgd among 142 D. melanogaster X chromosomes collected from several geographic regions including North Carolina, California, and Zimbabwe (Africa) [17].
• Epidemiology of high-level gentamicin resistant enterococcal isolates from Zimbabwe [18].
• We conducted a case control study at Harare Maternity Hospital, Zimbabwe. We genotyped a total of 171 cases with preeclampsia or eclampsia and 185 normotensive control subjects for the methylenetetrahydrofolate reductase (MTHFR) 677 C --> T genotype [5].
• Allele frequencies for six tetrameric short tandem repeat (STR) loci CSF1PO, TPOX, THO1, D3S1358, VWA, and FGA were determined in a Black African sample population from Zimbabwe. All loci are highly polymorphic and meet Hardy-Weinberg expectations [19].

Anatomical context of Zimbabwe

• In assessing the potential of the tetracycline compounds as biomarkers in oral rabies vaccination campaigns in jackals in Zimbabwe, the natural prevalence of fluorescent compounds in bone tissue from jackals was investigated [20].
• Outer membrane immunized cattle were protected significantly following challenge with 10(4) Zimbabwe strain parasitized erythrocytes, demonstrated by significant differences in prepatent period and peak rickettsemia compared with adjuvant immunized control cattle [21].
• CONCLUSION: The results of this study suggest that naked eye inspection of the cervix after application of acetic acid is a practical alternative to cervical cytology in screening for cervical cancer in countries with few resources like Zimbabwe [22].
• Enumeration of CD4 and CD8 T-cells in HIV infection in Zimbabwe using a manual immunocytochemical method [23].
• An evaluation of DDT and DDT residues in human breast milk in the Kariba Valley of Zimbabwe [24].

Associations of Zimbabwe with chemical compounds

• The activity of these hepatic enzymes was tested in 45 Shona children from a rural area of Zimbabwe with use of caffeine as a probe [25].
• RESULTS: Mean angiotensinogen levels varied widely across groups (Nigeria 1381 ng/ml angiotensin I generated, Zimbabwe 1638 ng/ml angiotensin I generated, Jamaica 1808 ng/ml angiotensin I generated, and Maywood 2039 ng/ml angiotensin I generated) [26].
• Two clones were evaluated; pCS20 from Crystal Springs (Zimbabwe) strain DNA had a 1,306-bp insert, and pCR9 from Kiswani (Kenya) strain DNA had a 754-bp insert [27].
• Sulphur and carbon isotopic analyses on small samples of kerogens and sulphide minerals from biogenic and non-biogenic sediments of the 2.7 x 10(9) years(Ga)-old Belingwe Greenstone Belt (Zimbabwe) imply that a complex biological sulphur cycle was in operation [28].
• Eight of 28 (29%) rectal swab specimens obtained from hospitalized patients in Zimbabwe had gentamicin resistant enterococci [18].

Gene context of Zimbabwe

• Distribution of HLA-DQA1, -DQB1 and DRB1 alleles in black IDDM patients and controls from Zimbabwe [29].
• Association of high HIV-1 RNA levels and homozygosity at HLA class II DRB1 in adults coinfected with Mycobacterium tuberculosis in Harare, Zimbabwe [30].
• Allele frequencies for the seven PCR-based loci (LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, and D1S80) were determined in a Black African population from Zimbabwe. All loci are highly polymorphic and meet Hardy-Weinberg expectations [31].
• Low CYP1A2 activity in rural Shona children of Zimbabwe [25].
• Sequence-specific oligonucleotide typing in Shona patients with rheumatoid arthritis and healthy controls from Zimbabwe [32].

Analytical, diagnostic and therapeutic context of Zimbabwe

• Further validation of the recombinant MAP1-B-based ELISA was done with sera obtained from sheep raised in heartwater-free areas in Zimbabwe and from several Caribbean islands [33].
• Compliance with malaria chemoprophylaxis programmes was studied in the National Railways and two large commercial farm labour forces in Zimbabwe. Prophylaxis was primarily conducted using pyrimethamine/dapsone and the study measured compliance rates through interview and the detection of drug in the urine [34].
• Ketamine drip anaesthesia for caesarean section. Report on 200 cases from a rural hospital in Zimbabwe [35].
• A case of dual chloroquine and halofantrine treatment failure in Zimbabwe [36].
• Five hundred and ten cattle were immunised using the Theileria parva (Boleni) stock without concurrent chemotherapy with tetracycline on 2 farms in Zimbabwe, both of which had a history of theileriosis [37].

References