Psychiatry related information on Sperm Transport

• It is concluded that has3 is expressed by the porcine endosalpinx epithelium and the levels of expression do not vary during the critical periods of sperm transport and fertilization, despite fluctuating levels of HA in the tubal fluid at corresponding periods [1].

High impact information on Sperm Transport

• Alteration of epididymal sperm transport and maturation in mice by oestrogen and testosterone [2].
• Vaginocervical stimulation affects progesterone secretion, sperm transport, sexual receptivity, locomotion, and perception of pain in female rats [3].
• Epididymis is a sex steroid (androgen + estrogen)-sensitive duct provided with spontaneous motility, allowing sperm transport [4].
• Fra1 activity in the frog, Rana esculenta, testis: a new potential role in sperm transport [5].
• We report for the first time in a vertebrate, experimental evidence showing that the expression of Fra1 is related to peritubular myoid cells during sperm transport from the tubular compartment to efferent ducts [5].

Biological context of Sperm Transport

• Mating-induced increments in androgen secretion at these times may enhance subsequent reproductive success by facilitating males' intromissive capacity, which is required for the induction of ovulation and optimal sperm transport in female partners [6].
• P20-44 of CAP37 may be useful in investigating the regulation of human sperm motility and to construct "hybrid peptides" with enhanced potency as a component of vaginal contraceptive that could doubly be effective by killing infectious agents and inhibiting sperm transport [7].
• Sperm death and inhibition of sperm transport in the cervix of ewes in estrus after removal of the corpus luteum-bearing ovary [8].
• The mechanisms by which PGF2alpha affect these parameters have not yet been elucidated, but it is possible that the sperm transport after insemination is increased [9].
• These differences suggest that in males, developmental manipulations of OT may have the potential to influence the subsequent expression of sexual behavior and sperm transport [10].

Anatomical context of Sperm Transport

• Within the small (6 mm) fallopian tube, the isthmus and ampulla are sharply delineated by their contractile activity and epithelial character; there is evidence of some sperm entry into isthmic crypts and a tendency for ipsilateral ovarian control of sperm transport to the tubal ampulla [11].
• Oxytocin is present in the mammalian testis where it increases contractility of seminiferous tubules in vitro and has been implicated in sperm transport [12].
• Treatment with progesterone did not affect fertility, cervical mucus or sperm transport, but diminished the histological abnormalities produced by oestradiol (P less than 0.05) [13].
• We suggest that the Leydig cells are the main source of oxytocin immunoreactivity in the testis and that this oxytocin is involved in modulating seminiferous tubule movements and the resultant sperm transport [14].
• In the excretory ducts of the testis (ductus epididymidis, vas deferens and its associated seminal vesicles), the major signals were seen with antibodies to P2X1 and P2X2 in the membranes of the smooth muscle layer, suggesting that these receptors are involved in the process of sperm transport and ejaculation [15].

Associations of Sperm Transport with chemical compounds

• Improvement of sperm transport in estrous rabbits by exogenous estradiol [16].
• The results indicate that epididymal sperm transport is enhanced after androgen withdrawal [17].
• Rapid sperm transport was effectively blocked with the alpha-adrenergic antagonist phenoxybenzamine [18].
• Ovulation, sperm transport, and fertilization occur normally in capsaicin-treated rats [19].
• These data suggest that CS2 does not exert a direct effect on the testes, but rather may interfere with the processes regulating sperm transport and ejaculation [20].

Gene context of Sperm Transport

• These findings suggest that both OT and AVP may have a role in regulating epididymal contractility and thus, perhaps, sperm transport through that organ [21].
• Synthesis, processing, and subcellular localization of mouse ADAM3 during spermatogenesis and epididymal sperm transport [22].
• In this study, we investigate Tex101 mRNA expression in the adult mouse testis using in situ hybridization, and we examine the fate of TEX101 during sperm transport by immunohistochemical and Western blot analyses [23].
• Effects of oxytocin on sperm transport in the pubertal rat [12].
• Overall, the observations suggest that cytoskeletal activity of the Sertoli cell is important for several aspects of the spermiation process as well as sperm transport [24].

Analytical, diagnostic and therapeutic context of Sperm Transport

• Because of suggestions that estradiol improves sperm transport, estradiol-17 beta was given to mature ewes at progestagen-induced estrus to test effects on fertility after artificial insemination with frozen semen [25].

References