Disease relevance of Petromyzon

• Tissue levels of bilirubin and biliverdin in the sea lamprey, Petromyzon marinus L., before and after biliary atresia [1].

High impact information on Petromyzon

• In addition, a PU.1-like gene has been identified in a jawless vertebrate, Petromyzon marinus (sea lamprey) [2].
• Toward this end, we have cloned Dlx genes from the lamprey Petromyzon marinus, an agnathan vertebrate that occupies a critical phylogenetic position between cephalochordates and gnathostomes [3].
• Petromyzonol sulfate and its derivatives: the chemoattractants of the sea lamprey [4].
• An Ikaros-related gene has been identified in Petromyzon marinus (sea lamprey), a jawless vertebrate species, in which neither Ig nor TCRs have been identified [5].
• A full-length transcript encoding a functional type II GnRH receptor was cloned from the pituitary of the sea lamprey, Petromyzon marinus [6].

Biological context of Petromyzon

• Molecular evolution of the rhodopsin gene of marine lamprey, Petromyzon marinus [7].
• These results demonstrate that chloride/bicarbonate exchange limitations and possibly active transport of protons contribute to the unique CO2 transport properties in the blood of the lamprey, Petromyzon marinus [8].
• Thus, Met-enkephalin staining in Petromyzon is a general property of cells in the rostral pars distalis both in larvae and adults and cannot be correlated with such events in the life cycle as metamorphosis or reproduction [9].
• Gonadotropin-releasing hormone (GnRH) concentrations were measured in brains of adult male sea lamprey, Petromyzon marinus, during their final reproductive period [10].
• Thyroid hormone clearance kinetics in adult sea lampreys, Petromyzon marinus [11].

Anatomical context of Petromyzon

• The development of neurons expressing gamma-aminobutyric acid (GABA) in the rhombencephalon and spinal cord of the sea lamprey (Petromyzon marinus) was studied for the first time with an anti-GABA antibody [12].
• Nitric oxide synthase in the olfactory mucosa of the larval sea lamprey (Petromyzon marinus) [13].
• Here, the development of the forebrain and midbrain gamma-aminobutyric acid (GABA)-ergic systems was studied in embryos, prolarvae, and small larvae of the sea lamprey using an anti-GABA antibody [14].
• In this study, serotonin (5-hydroxytryptamine; 5HT)-immunoreactive (5HT-IR) neuronal fibers were identified in the primary olfactory pathway of the sea lamprey [15].
• Horseradish peroxidase (HRP), fluorescein-, or Texas red-(TRDA) coupled dextran-amine applied into the oculomotor nucleus of larval lamprey (Petromyzon marinus) retrogradely labeled two populations of contralateral abducens interneurons, one lateral and the other periventricular [16].

Associations of Petromyzon with chemical compounds

• An analysis of the interrelationship of nuclear and plasma triiodothyronine in the sea lamprey, lake trout, and rat: evolutionary considerations [17].
• Characterization and localization of gonadotropin-releasing hormone receptors in the adult female sea lamprey, Petromyzon marinus [18].
• Glutamic acid decarboxylase in sea lamprey (Petromyzon marinus): characterization, localization, and developmental changes [19].
• A novel homodimeric glycoprotein was isolated and characterized from the pituitaries of adult sea lampreys, Petromyzon marinus, modern representatives of the earliest vertebrates [20].
• Ontogeny of 5-HT neurons in the brainstem of the lamprey, Petromyzon marinus [21].

Gene context of Petromyzon

• We report the cloning of VDR from Petromyzon marinus, an unexpected finding because lampreys lack mineralized tissues and hair [22].
• We characterized the sequence and expression pattern of BMP2/4 class genes in the sea lamprey, Petromyzon marinus [23].
• A peptide belonging to the pancreatic-polypeptide-fold family of regulatory peptides has been isolated from the intestine of an Agnathan, the sea lamprey (Petromyzon marinus) [24].
• Cloning and characterization of a functional type II gonadotropin-releasing hormone receptor with a lengthy carboxy-terminal tail from an ancestral vertebrate, the sea lamprey [6].
• Here we report the isolation of a Pitx gene, PitxA, from two lamprey species, Lampetra planeri and Petromyzon marinus [25].

Analytical, diagnostic and therapeutic context of Petromyzon

• The distribution of estrogen target neurons is assessed in the forebrain of larval sea lamprey, Petromyzon marinus, by the use of thaw-mount autoradiography [26].
• Melatonin secretion from cultured pineal complexes of the lamprey, Petromyzon marinus, was measured by radioimmunoassay (RIA) for 6 days under either a 12:12 light:dark cycle (L:D) or continuous darkness (D:D) at either 10 degrees or 20 degrees [27].
• In in vivo studies, GABA or muscimol injected at 200 microg/kg significantly increased lamprey GnRH concentration in the brain 0.5 h after treatment compared to controls in female sea lampreys [28].
• In this study we examined the spatial relationship of GABA-containing and GnRH-containing neurons by immunocytochemistry and in situ hybridization in larval and adult brains of sea lamprey, Petromyzon marinus [29].
• Plasma estradiol and progesterone after hypophysectomy and substitution with pituitary in female sea lampreys (Petromyzon marinus) [30].

References