Disease relevance of Heart Septal Defects, Ventricular

• The patient diagnoses were transposition of the great arteries (n = 20), tetralogy of Fallot (n = 38), coarctation of the aorta (n = 24), complete atrioventricular (AV) canal (n = 15), atrial septal defect (n = 8), ventricular septal defects (n = 3), pulmonary stenosis (n = 4), aortic stenosis (n = 8) and subaortic stenosis (n = 9) [1].
• We present a female infant with (1) abnormal facies: microcephaly, blepharophimosis, small, low set, posteriorly rotated ears, bulbous nose, carp shaped mouth, micrognathia; (2) congenital heart abnormalities: large atrial and ventricular septal defects; (3) congenital hypothyroidism; (4) severe global retardation [2].
• There were inverse associations between carbon monoxide and isolated atrial septal defects and between ozone and isolated ventricular septal defects [3].
• This paper reviews the scientific literature concerning the exercise capabilities and the cardiorespiratory adjustments to exercise in patients surgically corrected for 4 of the most common congenital heart lesions: isolated atrial septal defect, isolated ventricular septal defects, pulmonary stenosis and tetralogy of Fallot [4].
• Fourth, it was confirmed that the type of cardiac fistula occurring most commonly following penetrating cardiac trauma was a ventricular septal defect and that conservative management of small ventricular septal defects is compatible with a prolonged asymptomatic course [5].

High impact information on Heart Septal Defects, Ventricular

• Thus, we conclude that control SVR is important for prediction of the hemodynamic effects of afterload reduction by hydralazine in infants and young children with large ventricular septal defects, and that this drug may be beneficial in patients with high control SVRs since a high SVR brings about a decrease in the Qp/Qs ratio [6].
• 2) Specialized A-V conduction system electrograms were never delineated posterior to the ventricular septal defect, in contradistinction to this usual location in hearts having ventricular septal defects associated with other congenital lesions [7].
• We studied the response of the renin-angiotensin system (RAS) to a surgically created ventricular septal defect (VSD) in immature ovines and also the role of angiotensin II in the pathophysiology of VSD in the chronically instrumented ovine [8].
• OBJECTIVES: We sought to report the results of a U.S. registry of device closure of congenital muscular ventricular septal defects (VSDs) using the new Amplatzer mVSD occluder (AGA Medical Corp., Golden Valley, Minnesota) [9].
• Mice lacking Meltrin beta exhibit ventricular septal defect (VSD) and immature valves, and most of the animals die soon after birth [10].

Chemical compound and disease context of Heart Septal Defects, Ventricular

• Inotropic support with digoxin is commonly used in patients with left ventricular volume overload due to ventricular septal defect (VSD) [11].
• Effects of captopril on the distribution of left ventricular output with ventricular septal defect [12].
• Hemodynamic consequences of inotropic support with digoxin or amrinone in lambs with ventricular septal defect [11].
• OBJECTIVE: To test the hypothesis that cardiopulmonary bypass used for repair of ventricular septal defects and atrioventricular septal defects would decrease availability of urea cycle intermediates including arginine and subsequent nitric oxide availability [13].
• Nitroprusside abolishes the deleterious effects of surface cooling-induced hypothermia on immature pigs with ventricular septal defects [14].

Biological context of Heart Septal Defects, Ventricular

• The hemodynamic effects of hydralazine were studied in 17 infants and young children with ventricular septal defects to clarify the significance of systemic vascular resistance (SVR) in determining these effects [6].
• Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione [15].

Anatomical context of Heart Septal Defects, Ventricular

• The association between aortic regurgitation (AR) and VSD has often been described, but that between a stenosed aortic valve and VSD has been rarely observed, although bicuspid aortic valves and ventricular septal defects are probably the two most common congenital heart defects [16].
• We report on a patient with pre- and postnatal growth retardation, bilateral symmetrical ulnar agenesis with monodactyly, atrial septal defect, two ventricular septal defects, Wolff-Parkinson-White conduction abnormality, and abnormal configuration of the pancreas [17].
• A case of parachute mitral valve (PMV) associated with multiple muscular ventricular septal defects (VSDs) is reported in a 16-year-old girl who presented with dyspnea and a cardiac murmur [18].
• Strain-dependent effect of ethanol on ventricular septal defect frequency in White Leghorn chick embryos [19].
• Device closure of iatrogenic membranous ventricular septal defects after prosthetic aortic valve replacement using the Amplatzer membranous ventricular septal defect occluder [20].

Gene context of Heart Septal Defects, Ventricular

• The technique was useful in distinguishing different forms of atrial septal defect and identifying muscular ventricular septal defects that were difficult to image directly [21].
• BACKGROUND: This study investigated changes in left ventricular (LV) geometry and systolic function after corrective surgery for atrial (ASD) and ventricular septal defects (VSD) [22].
• BACKGROUND: Apical ventricular septal defects (VSDs) are difficult to visualize and close transatrially [23].
• BACKGROUND: Congenital heart lesions with multiple ventricular septal defects remain a surgical challenge [24].
• PDS (polydioxine) resorbable pledgets and strips, provided by Ethicon GmbH, were used as a suture support during the past 2 years for closure of 29 ventricular aneurysmectomies and four ischemic ventricular septal defects, all except one in combination with coronary bypass grafting [25].

Analytical, diagnostic and therapeutic context of Heart Septal Defects, Ventricular

• Transcatheter closure of membranous ventricular septal defects with a new nitinol prosthesis in a natural swine model [26].
• Device closure of congenital atrial and ventricular septal defects (ASDs and VSDs) and of postoperative residual interatrial and interventricular communications, balloon valvuloplasty, and Brockenbrough atrial septal puncture with ASD creation have been performed under combined fluoroscopic and TEE guidance [27].

References