The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Laminaria


High impact information on Laminaria

  • To generate a vaccine to protect against a variety of human pathogenic fungi, we conjugated laminarin (Lam), a well-characterized but poorly immunogenic beta-glucan preparation from the brown alga Laminaria digitata, with the diphtheria toxoid CRM197, a carrier protein used in some glyco-conjugate bacterial vaccines [6].
  • Components of Laminaria which might account for the observed difference in mammary tumor growth are varied and include the sulfated polysaccharide fucoidan . Rats in the top row of cages had a significant (p = 0.01) delay in time to tumor compared to rats in the lower four rows [7].
  • Different haloperoxidases, one specific for the oxidation of iodide and another that can oxidize both iodide and bromide, were separated from the sporophytes of the brown alga Laminaria digitata and purified to electrophoretic homogeneity [8].
  • Laminarin, a linear beta-1,3 glucan (mean degree of polymerization of 33) was extracted and purified from the brown alga Laminaria digitata [9].
  • Resonance Raman spectroscopy of a light-harvesting protein from the brown alga Laminaria saccharina [10].

Biological context of Laminaria


Anatomical context of Laminaria


Associations of Laminaria with chemical compounds

  • The N-terminus of the major polypeptide component of the light-harvesting complex (LHC) from the brown alga Laminaria saccharina is blocked [19].
  • Vanadium-dependent iodoperoxidases in Laminaria digitata, a novel biochemical function diverging from brown algal bromoperoxidases [20].
  • An aerobic, polarly flagellated marine bacterium that produces a prodigiosin-like pigment was isolated from the red-spotted culture beds of Laminaria japonica [21].
  • Experiments with the marine alga Laminaria digitata demonstrated that natural haloperoxidase systems are capable of mediating the deactivation of acylated homoserine lactones [22].
  • Procedures performed after laminaria were significantly faster than those after misoprostol (median 3.4 versus 7.2 minutes, respectively, P = .01) [11].

Gene context of Laminaria


Analytical, diagnostic and therapeutic context of Laminaria


  1. Gene structure of a chlorophyll a/c-binding protein from a brown alga: presence of an intron and phylogenetic implications. Caron, L., Douady, D., Quinet-Szely, M., de Goër, S., Berkaloff, C. J. Mol. Evol. (1996) [Pubmed]
  2. Differential blocking of coagulation-activating pathways of Limulus amebocyte lysate. Zhang, G.H., Baek, L., Buchardt, O., Koch, C. J. Clin. Microbiol. (1994) [Pubmed]
  3. Uterine rupture following midtrimester abortion by laminaria, prostaglandin F2alpha, and oxytocin: report of two cases. Propping, D., Stubblefield, P.G., Golub, J., Zuckerman, J. Am. J. Obstet. Gynecol. (1977) [Pubmed]
  4. Clostridial sepsis after abortion with PGF2alpha and intracervical laminaria tents--a case report. Green, S.L., Brenner, W.E. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. (1978) [Pubmed]
  5. Effects of pressure on bone resorption in the middle ear of rats. Moriyama, H., Huang, C.C., Kato, M., Abramson, M. The Annals of otology, rhinology, and laryngology. (1985) [Pubmed]
  6. A novel glyco-conjugate vaccine against fungal pathogens. Torosantucci, A., Bromuro, C., Chiani, P., De Bernardis, F., Berti, F., Galli, C., Norelli, F., Bellucci, C., Polonelli, L., Costantino, P., Rappuoli, R., Cassone, A. J. Exp. Med. (2005) [Pubmed]
  7. Dietary seaweed (Laminaria) and mammary carcinogenesis in rats. Teas, J., Harbison, M.L., Gelman, R.S. Cancer Res. (1984) [Pubmed]
  8. The brown algal kelp Laminaria digitata features distinct bromoperoxidase and iodoperoxidase activities. Colin, C., Leblanc, C., Wagner, E., Delage, L., Leize-Wagner, E., Van Dorsselaer, A., Kloareg, B., Potin, P. J. Biol. Chem. (2003) [Pubmed]
  9. Linear beta-1,3 glucans are elicitors of defense responses in tobacco. Klarzynski, O., Plesse, B., Joubert, J.M., Yvin, J.C., Kopp, M., Kloareg, B., Fritig, B. Plant Physiol. (2000) [Pubmed]
  10. Resonance Raman spectroscopy of a light-harvesting protein from the brown alga Laminaria saccharina. Pascal, A.A., Caron, L., Rousseau, B., Lapouge, K., Duval, J., Robert, B. Biochemistry (1998) [Pubmed]
  11. Misoprostol compared with laminaria before early second-trimester surgical abortion: a randomized trial. Goldberg, A.B., Drey, E.A., Whitaker, A.K., Kang, M.S., Meckstroth, K.R., Darney, P.D. Obstetrics and gynecology. (2005) [Pubmed]
  12. Cervical dilation from laminaria tents and synthetic osmotic dilators used for 6 hours before abortion. Kline, S.B., Meng, H., Munsick, R.A. Obstetrics and gynecology. (1995) [Pubmed]
  13. Functional and biochemical aspects of laminaria use in first-trimester pregnancy termination. Ye, B.L., Yamamoto, K., Tyson, J.E. Am. J. Obstet. Gynecol. (1982) [Pubmed]
  14. Increased rates of chorioamnionitis with extra-amniotic saline infusion method of labor induction. Levey, K.A., MacKenzie, A.P., Stephenson, C., Bercik, R., Kuczynski, E., Funai, E.F. Obstetrics and gynecology. (2004) [Pubmed]
  15. Cervical dilation before first-trimester elective abortion: a controlled comparison of meteneprost, laminaria, and hypan. Darney, P.D., Dorward, K. Obstetrics and gynecology. (1987) [Pubmed]
  16. A randomized controlled trial of laminaria, oral misoprostol, and vaginal misoprostol before abortion. MacIsaac, L., Grossman, D., Balistreri, E., Darney, P. Obstetrics and gynecology. (1999) [Pubmed]
  17. Plasma concentrations of oestrone, oestradiol, oestriol and progesterone during mechanical stretch-induced abortion at mid-trimester. Manabe, Y., Manabe, A., Aso, T. J. Endocrinol. (1981) [Pubmed]
  18. Placental and decidual u-PA, t-PA, PAI-1 and PAI-2 concentrations, as affected by cervical dilatation with laminaria tents or Hegar dilators. Jonasson, A., Larsson, B., Lecander, I., Astedt, B. Thromb. Res. (1989) [Pubmed]
  19. Fucoxanthin-chlorophyll a/c light-harvesting complexes of Laminaria saccharina: partial amino acid sequences and arrangement in thylakoid membranes. Douady, D., Rousseau, B., Caron, L. Biochemistry (1994) [Pubmed]
  20. Vanadium-dependent iodoperoxidases in Laminaria digitata, a novel biochemical function diverging from brown algal bromoperoxidases. Colin, C., Leblanc, C., Michel, G., Wagner, E., Leize-Wagner, E., Van Dorsselaer, A., Potin, P. J. Biol. Inorg. Chem. (2005) [Pubmed]
  21. Pseudoalteromonas bacteriolytica sp. nov., a marine bacterium that is the causative agent of red spot disease of Laminaria japonica. Sawabe, T., Makino, H., Tatsumi, M., Nakano, K., Tajima, K., Iqbal, M.M., Yumoto, I., Ezura, Y., Christen, R. Int. J. Syst. Bacteriol. (1998) [Pubmed]
  22. Reaction of acylated homoserine lactone bacterial signaling molecules with oxidized halogen antimicrobials. Borchardt, S.A., Allain, E.J., Michels, J.J., Stearns, G.W., Kelly, R.F., McCoy, W.F. Appl. Environ. Microbiol. (2001) [Pubmed]
  23. Biochemical changes in the cervical mucus after application of laminaria tent. El Maradny, E., Kanayama, N., Halim, A., Maehara, K., Kobayashi, T., Terao, T. Acta obstetricia et gynecologica Scandinavica. (1996) [Pubmed]
  24. The effect of cervical dilatation by laminaria tent in first trimester legal abortions on blood loss related to fibrinolytic activity in the decidua and placenta. Jonasson, A., Larsson, B., Lecander, I., Astedt, B. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. (1989) [Pubmed]
  25. Methods of cervical priming. Steiner, A.L., Creasy, R.K. Clinical obstetrics and gynecology. (1983) [Pubmed]
  26. Reducing the induction to abortion interval in termination of second trimester pregnancies: a comparison of mifepristone with laminaria tent. Ho, P.C., Tsang, S.S., Ma, H.K. British journal of obstetrics and gynaecology. (1995) [Pubmed]
  27. A comparison of misoprostol with and without laminaria tents for induction of second-trimester abortion. Jain, J.K., Mishell, D.R. Am. J. Obstet. Gynecol. (1996) [Pubmed]
  28. Plasma lidocaine levels following paracervical infiltration for aspiration abortion. Blanco, L.J., Reid, P.R., King, T.M. Obstetrics and gynecology. (1982) [Pubmed]
  29. Termination of second-trimester pregnancy by laminaria and intramuscular injections of 15-methyl PGF2 alpha or 16-phenoxy-omega-17,18,19, 20-tetranor PGE2 methyl sulfonylamide. A randomized study. Bygdeman, M., Christensen, N.J. Acta obstetricia et gynecologica Scandinavica. (1983) [Pubmed]
  30. Adequacy and safety of buccal misoprostol for cervical preparation prior to termination of second-trimester pregnancy. Patel, A., Talmont, E., Morfesis, J., Pelta, M., Gatter, M., Momtaz, M.R., Piotrowski, H., Cullins, V. Contraception. (2006) [Pubmed]
WikiGenes - Universities