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MeSH Review

Child Abuse

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Disease relevance of Child Abuse


Psychiatry related information on Child Abuse


High impact information on Child Abuse

  • The chemistry of child neglect: do oxytocin and vasopressin mediate the effects of early experience [11]?
  • BACKGROUND: Substance abuse has been called the dominant characteristic of families involved in child abuse cases, but the frequency with which childhood victims become adult victimizers remains uncertain [12].
  • These data suggest that apoptosis, as detected by the presence of cytochrome c in CSF, is uniquely prominent among the subset of TBI patients diagnosed with child abuse [1].
  • Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse [13].
  • These variables are reviewed, and an increased child abuse risk factor for children with IDDM is discussed [2].

Chemical compound and disease context of Child Abuse

  • Policymakers have responded to the increase in the prevalence of methamphetamine (MA) use and the associated social costs (such as crime and child abuse and neglect) by mandating a growing number of MA users to substance abuse treatment via the criminal justice system (CJS) and/or child protective service (CPS) agencies [14].

Biological context of Child Abuse

  • To assess physician attitudes and practices in controversial areas of child abuse and neglect, anonymous questionnaires were mailed to pediatricians, family practitioners, and emergency medicine physicians in Pima County (Tucson) and Arizona (statewide) [15].
  • Because passive inhalation of cocaine can produce measurable urine BZ concentrations, a positive urine screen does not necessarily indicate poisoning or intentional administration of the substance and therefore is not proof of child abuse or neglect [16].

Anatomical context of Child Abuse


Associations of Child Abuse with chemical compounds

  • In deciding seven recent landmark child abuse cases, the U.S. Supreme Court has addressed and sought to balance the inherent conflict between the constitutional rights of the defendant and the best interests of the child [18].
  • Young age and child abuse were associated with extremely high CSF glutamate concentrations after TBI [19].
  • Child abuse: parenteral hydrocarbon administration [20].
  • Cutaneous necrosis after contact with calcium chloride: a mistaken diagnosis of child abuse [21].
  • The jurisdiction of the Hannover Institute of Legal Medicine recently experienced an unusually high incidence of lethal child neglect, with three cases in a 5-month period in 1999 [22].

Gene context of Child Abuse


Analytical, diagnostic and therapeutic context of Child Abuse


  1. Cytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse. Satchell, M.A., Lai, Y., Kochanek, P.M., Wisniewski, S.R., Fink, E.L., Siedberg, N.A., Berger, R.P., DeKosky, S.T., Adelson, P.D., Clark, R.S. J. Cereb. Blood Flow Metab. (2005) [Pubmed]
  2. Insulin-dependent diabetes mellitus and child abuse: is there a relationship? Horan, P.F., Gwynn, C., Renzi, D. Diabetes Care (1986) [Pubmed]
  3. Capsicum and capsaicin--a review: case report of the use of hot peppers in child abuse. Tominack, R.L., Spyker, D.A. J. Toxicol. Clin. Toxicol. (1987) [Pubmed]
  4. An abused five-month-old girl: Hangman's fracture or congenital arch defect? van Rijn, R.R., Kool, D.R., de Witt Hamer, P.C., Majoie, C.B. The Journal of emergency medicine. (2005) [Pubmed]
  5. Cerebral infarction in child abuse. Diagnosis by technetium-99m methylene diphosphonate skeletal scintigraphy. Glasier, C.M., Seibert, J.J., Williamson, S.L. Clinical nuclear medicine. (1987) [Pubmed]
  6. Substance abuse and child abuse. Impact of addiction on the child. Bays, J. Pediatr. Clin. North Am. (1990) [Pubmed]
  7. Munchausen syndrome by proxy. The importance of behavioral characteristics in recognition and investigation. Chiczewski, D., Kelly, M. Emergency medical services. (2002) [Pubmed]
  8. Diagnostic value of a psychological test in cases of suspected child abuse. Geddis, D.C., Turner, I.F., Eardley, J. Arch. Dis. Child. (1977) [Pubmed]
  9. Minnesota Supreme Court restricts disclosures of group therapy sessions as evidence in child abuse prosecutions. Feinwachs, D., Kingrey, J., Kinney, E.D. Health law vigil. (1984) [Pubmed]
  10. The association between punitive childhood experiences and hyperactivity. Whitmore, E.A., Kramer, J.R., Knutson, J.F. Child abuse & neglect. (1993) [Pubmed]
  11. The chemistry of child neglect: do oxytocin and vasopressin mediate the effects of early experience? Carter, C.S. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  12. Victims as victimizers: physical aggression by persons with a history of childhood abuse. Clarke, J., Stein, M.D., Sobota, M., Marisi, M., Hanna, L. Arch. Intern. Med. (1999) [Pubmed]
  13. Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse. Newport, D.J., Heim, C., Bonsall, R., Miller, A.H., Nemeroff, C.B. Biol. Psychiatry (2004) [Pubmed]
  14. Coerced treatment for methamphetamine abuse: differential patient characteristics and outcomes. Brecht, M.L., Anglin, M.D., Dylan, M. The American journal of drug and alcohol abuse. (2005) [Pubmed]
  15. Statewide survey of physician attitudes to controversies about child abuse. Marshall, W.N., Locke, C. Child abuse & neglect. (1997) [Pubmed]
  16. Passive inhalation of cocaine by infants. Heidemann, S.M., Goetting, M.G. Henry Ford Hosp. Med. J. (1990) [Pubmed]
  17. Hemophagocytic lymphohistiocytosis masquerading as child abuse: presentation of three cases and review of central nervous system findings in hemophagocytic lymphohistiocytosis. Rooms, L., Fitzgerald, N., McClain, K.L. Pediatrics (2003) [Pubmed]
  18. The U.S. Supreme Court on victimized children: the constitutional rights of the defendant versus the best interests of the child. Kermani, E.J. Journal of the American Academy of Child and Adolescent Psychiatry. (1991) [Pubmed]
  19. Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse. Ruppel, R.A., Kochanek, P.M., Adelson, P.D., Rose, M.E., Wisniewski, S.R., Bell, M.J., Clark, R.S., Marion, D.W., Graham, S.H. J. Pediatr. (2001) [Pubmed]
  20. Child abuse: parenteral hydrocarbon administration. Saulsbury, F.T., Chobanian, M.C., Wilson, W.G. Pediatrics (1984) [Pubmed]
  21. Cutaneous necrosis after contact with calcium chloride: a mistaken diagnosis of child abuse. Zurbuchen, P., LeCoultre, C., Calza, A.M., Halpérin, n.u.l.l. Pediatrics (1996) [Pubmed]
  22. Lethal child neglect. Fieguth, A., Günther, D., Kleemann, W.J., Tröger, H.D. Forensic Sci. Int. (2002) [Pubmed]
  23. Soluble adhesion molecules in CSF are increased in children with severe head injury. Whalen, M.J., Carlos, T.M., Kochanek, P.M., Wisniewski, S.R., Bell, M.J., Carcillo, J.A., Clark, R.S., DeKosky, S.T., Adelson, P.D. J. Neurotrauma (1998) [Pubmed]
  24. Problems in interagency collaboration: lessons from a project that failed. Byles, J.A. Child abuse & neglect. (1985) [Pubmed]
  25. Ten-year study of pediatric drownings and near-drownings in King County, Washington: lessons in injury prevention. Quan, L., Gore, E.J., Wentz, K., Allen, J., Novack, A.H. Pediatrics (1989) [Pubmed]
  26. Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury. Whalen, M.J., Carlos, T.M., Kochanek, P.M., Wisniewski, S.R., Bell, M.J., Clark, R.S., DeKosky, S.T., Marion, D.W., Adelson, P.D. Crit. Care Med. (2000) [Pubmed]
  27. Nature and severity of physical harm caused by child abuse and neglect: results from the Canadian Incidence Study. Trocmé, N., MacMillan, H., Fallon, B., De Marco, R. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. (2003) [Pubmed]
  28. Child abuse as a stressor of pediatricians. Johnson, C.F. Pediatric emergency care. (1999) [Pubmed]
  29. Training paramedics: emergency care for children with special health care needs. Spaite, D.W., Karriker, K.J., Seng, M., Conroy, C., Battaglia, N., Tibbitts, M., Salik, R.M. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors. (2000) [Pubmed]
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