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MeSH Review

Osteoporosis, Postmenopausal

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Disease relevance of Osteoporosis, Postmenopausal


High impact information on Osteoporosis, Postmenopausal


Chemical compound and disease context of Osteoporosis, Postmenopausal


Biological context of Osteoporosis, Postmenopausal


Anatomical context of Osteoporosis, Postmenopausal


Gene context of Osteoporosis, Postmenopausal


Analytical, diagnostic and therapeutic context of Osteoporosis, Postmenopausal


  1. Increased osteoclast development after estrogen loss: mediation by interleukin-6. Jilka, R.L., Hangoc, G., Girasole, G., Passeri, G., Williams, D.C., Abrams, J.S., Boyce, B., Broxmeyer, H., Manolagas, S.C. Science (1992) [Pubmed]
  2. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. Harris, S.T., Watts, N.B., Genant, H.K., McKeever, C.D., Hangartner, T., Keller, M., Chesnut, C.H., Brown, J., Eriksen, E.F., Hoseyni, M.S., Axelrod, D.W., Miller, P.D. JAMA (1999) [Pubmed]
  3. Rational design of a receptor super-antagonist of human interleukin-6. Savino, R., Ciapponi, L., Lahm, A., Demartis, A., Cabibbo, A., Toniatti, C., Delmastro, P., Altamura, S., Ciliberto, G. EMBO J. (1994) [Pubmed]
  4. Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: a double-blind, placebo-controlled study. Delmas, P.D., Balena, R., Confravreux, E., Hardouin, C., Hardy, P., Bremond, A. J. Clin. Oncol. (1997) [Pubmed]
  5. Subclinical vitamin D deficiency in postmenopausal women with low vertebral bone mass. Villareal, D.T., Civitelli, R., Chines, A., Avioli, L.V. J. Clin. Endocrinol. Metab. (1991) [Pubmed]
  6. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. Neer, R.M., Arnaud, C.D., Zanchetta, J.R., Prince, R., Gaich, G.A., Reginster, J.Y., Hodsman, A.B., Eriksen, E.F., Ish-Shalom, S., Genant, H.K., Wang, O., Mitlak, B.H. N. Engl. J. Med. (2001) [Pubmed]
  7. Alendronate in postmenopausal osteoporosis. McGrath, H. N. Engl. J. Med. (1996) [Pubmed]
  8. Treatment of postmenopausal osteoporosis with calcitriol or calcium. Tilyard, M.W., Spears, G.F., Thomson, J., Dovey, S. N. Engl. J. Med. (1992) [Pubmed]
  9. Does calcium supplementation prevent postmenopausal bone loss? A double-blind, controlled clinical study. Riis, B., Thomsen, K., Christiansen, C. N. Engl. J. Med. (1987) [Pubmed]
  10. The effect of estrogen dose on postmenopausal bone loss. Horsman, A., Jones, M., Francis, R., Nordin, C. N. Engl. J. Med. (1983) [Pubmed]
  11. Contributions of aging and estrogen deficiency to postmenopausal bone loss. Dequeker, J., Geusens, P. N. Engl. J. Med. (1985) [Pubmed]
  12. Effect of the fluoride/calcium regimen on vertebral fracture occurrence in postmenopausal osteoporosis. Comparison with conventional therapy. Riggs, B.L., Seeman, E., Hodgson, S.F., Taves, D.R., O'Fallon, W.M. N. Engl. J. Med. (1982) [Pubmed]
  13. Ipriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial. Alexandersen, P., Toussaint, A., Christiansen, C., Devogelaer, J.P., Roux, C., Fechtenbaum, J., Gennari, C., Reginster, J.Y. JAMA (2001) [Pubmed]
  14. Skeletal uptake of diphosphonate. Method for prediction of post-menopausal osteoporosis. Fogelman, I., Bessent, R.G., Cohen, H.N., Hart, D.M., Lindsay, R. Lancet (1980) [Pubmed]
  15. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group. Liberman, U.A., Weiss, S.R., Bröll, J., Minne, H.W., Quan, H., Bell, N.H., Rodriguez-Portales, J., Downs, R.W., Dequeker, J., Favus, M. N. Engl. J. Med. (1995) [Pubmed]
  16. Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis. Brown, J.P., Delmas, P.D., Malaval, L., Edouard, C., Chapuy, M.C., Meunier, P.J. Lancet (1984) [Pubmed]
  17. Bone has a sexually dimorphic response to aromatase deficiency. Oz, O.K., Zerwekh, J.E., Fisher, C., Graves, K., Nanu, L., Millsaps, R., Simpson, E.R. J. Bone Miner. Res. (2000) [Pubmed]
  18. Vitamin D receptor gene polymorphisms are not related to bone turnover, rate of bone loss, and bone mass in postmenopausal women: the OFELY Study. Garnero, P., Borel, O., Sornay-Rendu, E., Arlot, M.E., Delmas, P.D. J. Bone Miner. Res. (1996) [Pubmed]
  19. Analysis of gene expression in human bone biopsies by polymerase chain reaction: evidence for enhanced cytokine expression in postmenopausal osteoporosis. Ralston, S.H. J. Bone Miner. Res. (1994) [Pubmed]
  20. Cortical remodeling following suppression of endogenous estrogen with analogs of gonadotrophin releasing hormone. Bell, K.L., Loveridge, N., Lindsay, P.C., Lunt, M., Garrahan, N., Compston, J.E., Reeve, J. J. Bone Miner. Res. (1997) [Pubmed]
  21. Attenuation of postmenopausal high turnover bone loss in patients with hypoparathyroidism. Fujiyama, K., Kiriyama, T., Ito, M., Nakata, K., Yamashita, S., Yokoyama, N., Nagataki, S. J. Clin. Endocrinol. Metab. (1995) [Pubmed]
  22. Bone turnover in cortical and trabecular bone in normal women and in women with osteoporosis. Israel, O., Lubushitzky, R., Frenkel, A., Iosilevsky, G., Bettman, L., Gips, S., Hardoff, R., Baron, E., Barzilai, D., Kolodny, G.M. J. Nucl. Med. (1994) [Pubmed]
  23. Expression of Interleukin-6 (IL-6) and IL-6 receptor mRNA in human bone samples from pre- and postmenopausal women. Seck, T., Diel, I., Bismar, H., Ziegler, R., Pfeilschifter, J. Bone (2002) [Pubmed]
  24. Estrogen production and action. Nelson, L.R., Bulun, S.E. J. Am. Acad. Dermatol. (2001) [Pubmed]
  25. Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta. Spotila, L.D., Constantinou, C.D., Sereda, L., Ganguly, A., Riggs, B.L., Prockop, D.J. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  26. Association of a haplotype (196Phe/532Ser) in the interleukin-1-receptor-associated kinase (IRAK1) gene with low radial bone mineral density in two independent populations. Ishida, R., Emi, M., Ezura, Y., Iwasaki, H., Yoshida, H., Suzuki, T., Hosoi, T., Inoue, S., Shiraki, M., Ito, H., Orimo, H. J. Bone Miner. Res. (2003) [Pubmed]
  27. Constrained analogs of osteogenic peptides. Willick, G.E., Morley, P., Whitfield, J.F. Current medicinal chemistry. (2004) [Pubmed]
  28. Monocytic secretion of interleukin-1 receptor antagonist in normal and osteoporotic women: effects of menopause and estrogen/progesterone therapy. Pacifici, R., Vannice, J.L., Rifas, L., Kimble, R.B. J. Clin. Endocrinol. Metab. (1993) [Pubmed]
  29. Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy. Hikiji, H., Ishii, S., Shindou, H., Takato, T., Shimizu, T. J. Clin. Invest. (2004) [Pubmed]
  30. Long-term estrogen replacement therapy prevents bone loss and fractures. Ettinger, B., Genant, H.K., Cann, C.E. Ann. Intern. Med. (1985) [Pubmed]
  31. Cyclical clodronate is effective in preventing postmenopausal bone loss: a comparative study with transcutaneous hormone replacement therapy. Filipponi, P., Pedetti, M., Fedeli, L., Cini, L., Palumbo, R., Boldrini, S., Massoni, C., Cristallini, S. J. Bone Miner. Res. (1995) [Pubmed]
  32. Tibolone, a steroid with a tissue-specific hormonal profile, completely prevents ovariectomy-induced bone loss in sexually mature rats. Ederveen, A.G., Kloosterboer, H.J. J. Bone Miner. Res. (1999) [Pubmed]
  33. Three monthly intravenous injections of ibandronate in the treatment of postmenopausal osteoporosis. Thiébaud, D., Burckhardt, P., Kriegbaum, H., Huss, H., Mulder, H., Juttmann, J.R., Schöter, K.H. Am. J. Med. (1997) [Pubmed]
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