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MeSH Review

Aortic Coarctation

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Disease relevance of Aortic Coarctation


Psychiatry related information on Aortic Coarctation


High impact information on Aortic Coarctation


Chemical compound and disease context of Aortic Coarctation

  • In the present study we analyzed the effects of angiotensin II blockade on afferent aortic nerve activity of CH and sham-operated groups treated chronically with vehicle or losartan (10 mg/kg per day p.o.). CH was induced by subdiaphragmatic aortic coarctation, and the treatments lasted 8 days (4 control and 4 experimental days) [12].
  • However, it is controversial as to whether kinins oppose the hypertensinogenic effect of deoxycorticosterone acetate plus salt (DOCA-salt) or aortic coarctation and whether they mediate both chronic antihypertensive and cardiac antihypertrophic effects of ACEi in hypertension [13].
  • Effects of exercise on plasma renin, aldosterone and catecholamines before and after surgery for aortic coarctation [14].
  • Exchangeable sodium and saralasin-blocking, plasma renin and aldosterone in pre- and postoperative young patients with aortic coarctation [15].
  • Type 1 receptor blockade was accomplished with DuP 753 given in the drinking water and type 2 blockade with PD 123319 delivered by osmotic minipumps beginning with the day of surgery until 72 hours after aortic coarctation [16].

Biological context of Aortic Coarctation


Anatomical context of Aortic Coarctation


Gene context of Aortic Coarctation


Analytical, diagnostic and therapeutic context of Aortic Coarctation


  1. Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress. Gálvez, A.S., Brunskill, E.W., Marreez, Y., Benner, B.J., Regula, K.M., Kirschenbaum, L.A., Dorn, G.W. J. Biol. Chem. (2006) [Pubmed]
  2. Hypertension increases insulin-like growth factor binding protein-4 mRNA levels in rat aorta. Anwar, A., Delafontaine, P. Hypertension (1994) [Pubmed]
  3. Role of kinins and nitric oxide in the antihypertrophic effect of ramipril. Rhaleb, N.E., Yang, X.P., Scicli, A.G., Carretero, O.A. Hypertension (1994) [Pubmed]
  4. Left-to-right shunt via left superior vena cava communication with left atrium. Lam, W., Danoviz, J., Witham, D., Wyndham, C., Rosen, K.M. Chest (1981) [Pubmed]
  5. The impact of interventional cardiology for the management of adults with congenital heart defects. Chessa, M., Carrozza, M., Butera, G., Negura, D., Piazza, L., Giamberti, A., Feslova, V., Bossone, E., Vigna, C., Carminati, M. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. (2006) [Pubmed]
  6. Decision making for the surgical management of aortic coarctation associated with ventricular septal defect. Brouwer, R.M., Cromme-Dijkhuis, A.H., Erasmus, M.E., Contant, C., Bogers, A.J., Elzenga, N.J., Ebels, T., Eijgelaar, A. J. Thorac. Cardiovasc. Surg. (1996) [Pubmed]
  7. Fibroblast growth factor-2 mediates pressure-induced hypertrophic response. Schultz, J.E., Witt, S.A., Nieman, M.L., Reiser, P.J., Engle, S.J., Zhou, M., Pawlowski, S.A., Lorenz, J.N., Kimball, T.R., Doetschman, T. J. Clin. Invest. (1999) [Pubmed]
  8. Changes in plasma catecholamines and dopamine beta-hydroxylase after corrective surgery for coarctation of the aorta. Benedict, C.R., Grahame-Smith, D.G., Fisher, A. Circulation (1978) [Pubmed]
  9. Resting and exercise renal blood flows in immature ovine aortic coarctation. Impact of gradient relief. Lock, J.E., Kulik, T.J., Green, T.P., Niemi, T., Einzig, S. Circ. Res. (1983) [Pubmed]
  10. Role of peripheral vasodilation in the hypotensive response to left ventriculography in anesthetized dogs. Shaw, D.D., Wolf, G.L., Baltaxe, H.A. Circ. Res. (1980) [Pubmed]
  11. Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice. Gessler, M., Knobeloch, K.P., Helisch, A., Amann, K., Schumacher, N., Rohde, E., Fischer, A., Leimeister, C. Curr. Biol. (2002) [Pubmed]
  12. Chronic AT1 receptor blockade alters aortic nerve activity in hypertension. dos Santos, C.M., Moreira, E.D., Krieger, E.M., Michelini, L.C. Hypertension (1998) [Pubmed]
  13. Effect of ACE inhibitor on DOCA-salt- and aortic coarctation-induced hypertension in mice: do kinin B2 receptors play a role? Rhaleb, N.E., Peng, H., Alfie, M.E., Shesely, E.G., Carretero, O.A. Hypertension (1999) [Pubmed]
  14. Effects of exercise on plasma renin, aldosterone and catecholamines before and after surgery for aortic coarctation. Sehested, J., Kornerup, H.J., Pedersen, E.B., Christensen, N.J. Eur. Heart J. (1983) [Pubmed]
  15. Exchangeable sodium and saralasin-blocking, plasma renin and aldosterone in pre- and postoperative young patients with aortic coarctation. Sehested, J., Kornerup, H.J., Pedersen, E.B. Eur. Heart J. (1982) [Pubmed]
  16. Angiotensin receptor regulates cardiac hypertrophy and transforming growth factor-beta 1 expression. Everett, A.D., Tufro-McReddie, A., Fisher, A., Gomez, R.A. Hypertension (1994) [Pubmed]
  17. Hemodynamic, neural, and humoral mechanisms of aortic coarctation hypertension in the rat. Lappe, R.W., Brody, M.J. J. Cardiovasc. Pharmacol. (1986) [Pubmed]
  18. Angiotensin I converting enzyme genotype affects ventricular remodelling in children with aortic coarctation. Zadinello, M., Greve, G., Liu, X.Q., Barbosa, J.R., Schulze-Neick, I., Wilkinson, J.L., Redington, A.N. Heart (2005) [Pubmed]
  19. Pharmacokinetic study of methyldopa in aorta-coarctated rats using a microdialysis technique. Opezzo, J.A., Höcht, C., Taira, C.A., Bramuglia, G.F. Pharmacol. Res. (2001) [Pubmed]
  20. Aortic coarctation, aortic valvular stenosis, and coronary artery disease: combined one-stage surgical therapy operation. Bartoccioni, S., Giombolini, C., Fiaschini, P., Martinelli, G., Fedeli, C., Di Lazzaro, D., Lanzillo, G., Possati, G. Journal of cardiac surgery. (1995) [Pubmed]
  21. A new strategy for the surgical treatment of aortic coarctation associated with ventricular septal defect in infants using an absorbable pulmonary artery band. Bonnet, D., Patkaï, J., Tamisier, D., Kachaner, J., Vouhé, P., Sidi, D. J. Am. Coll. Cardiol. (1999) [Pubmed]
  22. Atrial natriuretic peptide and its messenger ribonucleic acid in overloaded and overload-released ventricles of rat. Gu, J., D'Andrea, M., Seethapathy, M. Endocrinology (1989) [Pubmed]
  23. Left ventricular hypertrophy in rabbits does not exaggerate the effects of halothane on the intracellular components of cardiac contraction. Rooke, G.A., Su, J.Y. Anesthesiology (1992) [Pubmed]
  24. Effect of median eminence lesion on the hypertensive response due to acute aortic coarctation. Fregoneze, J.B., Salgado, M.C., Salgado, H.C. Am. J. Physiol. (1994) [Pubmed]
  25. Cyclooxygenase-2 and the renal renin-angiotensin system. Harris, R.C., Zhang, M.Z., Cheng, H.F. Acta Physiol. Scand. (2004) [Pubmed]
  26. The effect of aortic coarctation on expression of endothelin-1 and endothelin receptors in heart and lungs. Sirviö, M.L., Uhlenius, N., Stewen, P., Metsärinne, K., Fyhrquist, F. Blood Press. (1995) [Pubmed]
  27. Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity. Schultz, J.e.l. .J., Glascock, B.J., Witt, S.A., Nieman, M.L., Nattamai, K.J., Liu, L.H., Lorenz, J.N., Shull, G.E., Kimball, T.R., Periasamy, M. Am. J. Physiol. Heart Circ. Physiol. (2004) [Pubmed]
  28. Implications of anomalous right subclavian artery in the repair of neonatal aortic coarctation. Hjortdal, V.E., Khambadkone, S., de Leval, M.R., Tsang, V.T. Ann. Thorac. Surg. (2003) [Pubmed]
  29. Cerebral oxygen saturation before congenital heart surgery. Kurth, C.D., Steven, J.L., Montenegro, L.M., Watzman, H.M., Gaynor, J.W., Spray, T.L., Nicolson, S.C. Ann. Thorac. Surg. (2001) [Pubmed]
  30. Left-sided lesions after anatomic repair of transposition of the great arteries, ventricular septal defect, and coarctation: surgical factors. Mohammadi, S., Serraf, A., Belli, E., Aupecle, B., Capderou, A., Lacour-Gayet, F., Martinovic, I., Piot, D., Touchot, A., Losay, J., Planché, C. J. Thorac. Cardiovasc. Surg. (2004) [Pubmed]
  31. Role of balloon angioplasty in the treatment of aortic coarctation. Rao, P.S., Chopra, P.S. Ann. Thorac. Surg. (1991) [Pubmed]
  32. Renal vascular interaction of angiotensin II and prostaglandins in renovascular hypertension. Cruz, B.V., Escalante, B. J. Cardiovasc. Pharmacol. (1999) [Pubmed]
  33. Vasopressor mechanisms in acute aortic coarctation hypertension. Salgado, H.C., Fazan Júnior, R., Salgado, M.C. Braz. J. Med. Biol. Res. (1997) [Pubmed]
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