The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Gly-Leu     2-(2-aminoethanoylamino)-4- methyl...

Synonyms: GLY-DL-LEU, CHEMBL349098, ACMC-1BAF4, AG-G-66112, ACMC-209o4q, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Glycyl-d-leucine


High impact information on Glycyl-d-leucine


Biological context of Glycyl-d-leucine


Anatomical context of Glycyl-d-leucine


Associations of Glycyl-d-leucine with other chemical compounds


Gene context of Glycyl-d-leucine


Analytical, diagnostic and therapeutic context of Glycyl-d-leucine

  • Cathepsin D and three dipeptidases versus leucyl-glycine, glycyl-L-leucine and glycyl-glycine) were assayed in serial, microtome prepared frozen sections (+/- 125 micrograms fresh weight) and related to histological composition (Nissl stain), dry weight, total protein, and DNA content [22].


  1. Absorptive and digestive function of the jejunum after jejunoileal bypass for treatment of human obesity. Fogel, M.R., Ravitch, M.M., Adibi, S.A. Gastroenterology (1976) [Pubmed]
  2. Intestinal perfusion studies in tropical sprue. 1. Amino acid and dipeptide absorption. Hellier, M.D., Radhakrishnan, A.N., Ganapathy, V., Mathan, V.I., Baker, S.J. Gut (1976) [Pubmed]
  3. An in vivo effect of the metabolites L-alanine and glycyl-L-leucine on the properties of the lysyl-tRNA synthetase from Escherichia coli K-12. II. Kinetic evidence. Hirshfield, I.N., Yeh, F.M. Biochim. Biophys. Acta (1976) [Pubmed]
  4. Human intestinal brush border peptidases. Tobey, N., Heizer, W., Yeh, R., Huang, T.I., Hoffner, C. Gastroenterology (1985) [Pubmed]
  5. Mechanisms of glycyl-L-leucine uptake by guinea-pig small intestine: relative importance of intact-peptide transport. Himukai, M., Hoshi, T. J. Physiol. (Lond.) (1980) [Pubmed]
  6. The yeaS (leuE) gene of Escherichia coli encodes an exporter of leucine, and the Lrp protein regulates its expression. Kutukova, E.A., Livshits, V.A., Altman, I.P., Ptitsyn, L.R., Zyiatdinov, M.H., Tokmakova, I.L., Zakataeva, N.P. FEBS Lett. (2005) [Pubmed]
  7. Crystal structure of the dipeptide binding protein from Escherichia coli involved in active transport and chemotaxis. Dunten, P., Mowbray, S.L. Protein Sci. (1995) [Pubmed]
  8. Dipeptidase activity in the small intestinal mucosa during pregnancy and lactation in the rat. Rolls, B.A. Br. J. Nutr. (1975) [Pubmed]
  9. In vitro and in situ evidence for the contribution of Labrasol and Gelucire 44/14 on transport of cephalexin and cefoperazone by rat intestine. Koga, K., Kawashima, S., Murakami, M. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V. (2002) [Pubmed]
  10. Age-dependent change in intestinal absorption of dipeptides and their constituent amino acids in the guinea pig. Himukai, M., Konno, T., Hoshi, T. Pediatr. Res. (1980) [Pubmed]
  11. Interaction of amino acids with glycl-L-leucine hydrolysis and transport in monkey small intestine. Ganapathy, V., Radhakrishnan, A.N. Clin. Sci. (1979) [Pubmed]
  12. Glycyl-L-sarcosine absorption across ovine omasal epithelium during coincubation with other peptide substrates and volatile fatty acids. McCollum, M.Q., Webb, K.E. J. Anim. Sci. (1998) [Pubmed]
  13. Factors affecting the movement of amino acids and small peptides across the vascularly perfused Anuran small intestine. Cheeseman, C.I. J. Physiol. (Lond.) (1979) [Pubmed]
  14. Intestinal absorption of beta-alanine, anserine and carnosine in rats. Hama, T., Tamaki, N., Miyamoto, F., Kita, M., Tsunemori, F. J. Nutr. Sci. Vitaminol. (1976) [Pubmed]
  15. Intracellular hydrolysis of peptides. Josefsson, L., Sjöström, H., Norén, O. Ciba Found. Symp. (1977) [Pubmed]
  16. Methacrylate gels with epoxide groups as supports for immobilization of enzymes in pH range 3-12. Turková, J., Bláha, K., Malaníková, M., Vancurová, D., Svec, F., Kálal, J. Biochim. Biophys. Acta (1978) [Pubmed]
  17. Two modes of metabolic regulation of lysyl-transfer ribonucleic acid synthetase in Escherichia coli K-12. Hirshfield, I.N., Liu, C., Yeh, F.M. J. Bacteriol. (1977) [Pubmed]
  18. Peptide-gap inhibitors: I. Competitive inhibition of aminopeptidase M by a hydrolytically resistant dipeptide analogue of glycylleucine. Fok, K.F., Yankeelov, J.A. Biochem. Biophys. Res. Commun. (1977) [Pubmed]
  19. Intestinal enzyme activity in lambs chronically infected with Trichostrongylus colubriformis: effect of anthelmintic treatment. Jones, D.G. Vet. Parasitol. (1983) [Pubmed]
  20. An in vivo effect of the metabolites L-alanine and glycyl-L-leucine on the properties of lysyl-tRNA synthetase from Escherichia coli K-12. I. Influence on subunit composition and molecular weight distribution. Hirshfield, I.N., Yeh, F.M., Zamecnik, P.C. Biochim. Biophys. Acta (1976) [Pubmed]
  21. Temperature dependent characteristics of intestinal glycyl-L-leucine dipeptidase in boreal zone fish. Gelman, A., Kuz'mina, V., Drabkin, V., Glatman, L. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2003) [Pubmed]
  22. Protease activities in normal and schizophrenic human prefrontal cortex and white matter. Pope, A., Amelotte, J.A., Belfer, H., Nixon, R.A. Neurochem. Res. (1981) [Pubmed]
WikiGenes - Universities