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Chemical Compound Review

Arachate     icosanoic acid

Synonyms: arachidate, Arachinsaeure, n-eicosanoate, Arachidic acid, Icosanoic acid, ...
 
 
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High impact information on arachidonic acid

  • A catalase monolayer adsorbed on a layer of arachidic acid deposited on a solid support was irradiated with 100 keV electrons simulating the conditions of electron microscopic imaging [1].
  • Analysis of the ceramide moiety by electron-impact mass spectrometry revealed the dominant fatty acid and sphingoid to be arachidic acid (C20:0) and tetradecasphing-4-enine, respectively [2].
  • Particle-rod hybrids: growth of arachidic acid molecular rods from capped cadmium selenide nanoparticles [3].
  • The other fatty acids were not significantly associated with adiponectin except for eicosanoic acid (C20:1 omega-9), which was significantly and positively associated with adiponectin in all individuals (r = 0.23; P = 0.01) [4].
  • In keeping with the fact that cPLA2 displays substrate specificity for arachidonyl-containing phospholipids, the arachidic acid analogue C19H39COCF3 is a considerably less potent inhibitor compared to AACOCF3.(ABSTRACT TRUNCATED AT 250 WORDS)[5]
 

Biological context of arachidonic acid

 

Anatomical context of arachidonic acid

 

Associations of arachidonic acid with other chemical compounds

 

Gene context of arachidonic acid

  • An analysis of the resonance x-ray diffraction effect is presented, whereby the location of the heme-Fe atoms within the electron density profile of the cytochrome c/arachidic acid ultrathin multilayer film is indicated to +/- 3 A accuracy [19].
  • One mixture contained naturally-occurring unsaturated fatty acyl chains and the other contained a mixture of 20:4, all of its partially hydrogenated analogues (20:3, 20:2, and 20:1), and arachidic acid (20:0) [20].
  • Here an intense tunable source of x-rays (beam line X9-A at the National Synchrotron Light Source at the Brookhaven National Laboratory) was utilized to measure the resonance x-ray diffraction effect from the heme-Fe atoms within the cytochrome c molecular monolayer located on the carboxyl surface of a five monolayer arachidic acid film [19].
  • The target molecule, bis (benzimidazo) thioperylene (BZP), is dispersed in an arachidic acid monomolecular layer containing one BZP molecule per microm2, which is also the probing area of the Raman microscope [21].
  • In case of arachidic acid the LFA-1 expression had also decreased [12].
 

Analytical, diagnostic and therapeutic context of arachidonic acid

References

  1. Inactivation of catalase monolayers by irradiation with 100 keV electrons. Hahn, M., Seredynski, J., Baumeister, W. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
  2. Glycosphingolipids in insects. Chemical structures of ceramide tetra-, penta-, hexa-, and heptasaccharides from Calliphora vicina pupae (Insecta: Diptera). Dennis, R.D., Geyer, R., Egge, H., Peter-Katalinic, J., Li, S.C., Stirm, S., Wiegandt, H. J. Biol. Chem. (1985) [Pubmed]
  3. Particle-rod hybrids: growth of arachidic acid molecular rods from capped cadmium selenide nanoparticles. Chen, D., Wang, R., Arachchige, I., Mao, G., Brock, S.L. J. Am. Chem. Soc. (2004) [Pubmed]
  4. Circulating adiponectin and plasma fatty acid profile. Fernández-Real, J.M., Vendrell, J., Ricart, W. Clin. Chem. (2005) [Pubmed]
  5. Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2. Street, I.P., Lin, H.K., Laliberté, F., Ghomashchi, F., Wang, Z., Perrier, H., Tremblay, N.M., Huang, Z., Weech, P.K., Gelb, M.H. Biochemistry (1993) [Pubmed]
  6. Studies on glycosphingolipids in larvae of the green-bottle fly, Lucilia caesar: two neutral glycosphingolipids having large straight oligosaccharide chains with eight and nine sugars. Sugita, M., Inagaki, F., Naito, H., Hori, T. J. Biochem. (1990) [Pubmed]
  7. Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids. Ballistreri, A., Giuffrida, M., Guglielmino, S.P., Carnazza, S., Ferreri, A., Impallomeni, G. Int. J. Biol. Macromol. (2001) [Pubmed]
  8. Inhibition of brain prostaglandin D synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids. Osama, H., Narumiya, S., Hayaishi, O., Iinuma, H., Takeuchi, T., Umezawa, H. Biochim. Biophys. Acta (1983) [Pubmed]
  9. Lipid composition and fluidity of plasma membranes isolated from corn (Zea mays L.) roots. Bohn, M., Heinz, E., Lüthje, S. Arch. Biochem. Biophys. (2001) [Pubmed]
  10. Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus. Almeida, T., Cunha, R.A., Ribeiro, J.A. Brain Res. (1999) [Pubmed]
  11. Altered fatty acid membrane composition modifies lymphocyte localization in vivo. Novo, C., Fonseca, E., Freitas, A.A. Cell. Immunol. (1987) [Pubmed]
  12. The fatty acid composition of the lymphocyte cell membrane. Influence on interactions with high endothelium and the expression of homing receptors. Twisk, A.J., Detering, F., Kraal, G. Immunobiology (1991) [Pubmed]
  13. Uptake of arachidonic acid, arachidic acid, oleic acid and their incorporation into phospholipids and triacylglycerols of isolated murine hepatocytes. Effect of thrombin-antithrombin III complex. Mandl, J., Tanács, B., Spolarics, Z., Garzó, T., Mucha, I., Antoni, F., Machovich, R., Horváth, I. Thromb. Res. (1984) [Pubmed]
  14. Facilitation of GABA release by arachidonic acid in rat hippocampal synaptosomes. Cunha, R.A., Ribeiro, J.A. Eur. J. Neurosci. (1999) [Pubmed]
  15. Infrared spectroscopy analysis of the structure of multilayer Langmuir-Blodgett films: effect of deposition velocity and pH. Diaz, M.E., Johnson, B., Chittur, K., Cerro, R.L. Langmuir : the ACS journal of surfaces and colloids. (2005) [Pubmed]
  16. Effect of fatty acid chain length and saturation on formation of the acylenzyme complex by the isolated aortic enzyme fraction. Swidzińska, K., Patelski, J., Szwajca, T. Acta physiologica Polonica. (1989) [Pubmed]
  17. Gas chromatography-mass spectrometric determination of fatty acids in seed oil of winged bean (Psophocarpus tetragonolobus (L.) DC). Higuchi, M., Terao, J., Iwai, K. J. Nutr. Sci. Vitaminol. (1982) [Pubmed]
  18. Effects of retinol, fatty acids and glycerol monooleate on the fusion of chick embryo myoblasts in vitro. Nakornchai, S., Falconer, A.R., Fisher, D., Goodall, A.H., Hallinan, T., Lucy, J.A. Biochim. Biophys. Acta (1981) [Pubmed]
  19. Location of the heme-Fe atoms within the profile structure of a monolayer of cytochrome c bound to the surface of an ultrathin lipid multilayer film. Pachence, J.M., Fischetti, R.F., Blasie, J.K. Biophys. J. (1989) [Pubmed]
  20. Processive interfacial catalysis by mammalian 85-kilodalton phospholipase A2 enzymes on product-containing vesicles: application to the determination of substrate preferences. Hanel, A.M., Schüttel, S., Gelb, M.H. Biochemistry (1993) [Pubmed]
  21. Surface-enhanced resonance raman scattering: single-molecule detection in a Langmuir-Blodgett monolayer. Constantino, C.J., Lemma, T., Antunes, P.A., Goulet, P., Aroca, R. Applied spectroscopy. (2003) [Pubmed]
  22. Docosahexaenoic acid stabilizes soluble amyloid-beta protofibrils and sustains amyloid-beta-induced neurotoxicity in vitro. Johansson, A.S., Garlind, A., Berglind-Dehlin, F., Karlsson, G., Edwards, K., Gellerfors, P., Ekholm-Pettersson, F., Palmblad, J., Lannfelt, L. FEBS J. (2007) [Pubmed]
 
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