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MeSH Review

Waist-Hip Ratio

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Disease relevance of Waist-Hip Ratio


Psychiatry related information on Waist-Hip Ratio


High impact information on Waist-Hip Ratio


Chemical compound and disease context of Waist-Hip Ratio


Biological context of Waist-Hip Ratio


Anatomical context of Waist-Hip Ratio


Associations of Waist-Hip Ratio with chemical compounds

  • OBJECTIVE--To determine if individuals who are overall obese but have low waist-to-hip ratios have unfavorable lipid profiles, blood pressures, and glucose statuses [29].
  • After adjustment for potentially confounding covariates, there were no significant differences between estrogen users and nonusers in BMI at follow-up, change in weight or BMI between baseline and follow-up, or waist-hip ratio or fat mass at follow-up [30].
  • Multiple regression analyses indicated that percent body fat, waist to hip ratio, plasma insulin, gender and renal function (1/creatinine), but not insulin sensitivity, were significant and independent determinants of plasma leptin level [31].
  • In stepwise regression modeling waist-to-hip ratio was most significantly related to peak GH in response to GHRH + arginine in HIV-infected men [32].
  • Waist to hip ratio paralleled the change in daylight and temperature, with the highest values during the summer and was thus inversely related to the seasonal testosterone variation [33].

Gene context of Waist-Hip Ratio


Analytical, diagnostic and therapeutic context of Waist-Hip Ratio


  1. Nontraditional risk factors for coronary heart disease incidence among persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. Saito, I., Folsom, A.R., Brancati, F.L., Duncan, B.B., Chambless, L.E., McGovern, P.G. Ann. Intern. Med. (2000) [Pubmed]
  2. Effects of metformin or gemfibrozil on the lipodystrophy of HIV-infected patients receiving protease inhibitors. Martínez, E., Domingo, P., Ribera, E., Milinkovic, A., Arroyo, J.A., Conget, I., Pérez-Cuevas, J.B., Casamitjana, R., de Lazzari, E., Bianchi, L., Montserrat, E., Roca, M., Burgos, R., Arnaiz, J.A., Gatell, J.M. Antivir. Ther. (Lond.) (2003) [Pubmed]
  3. NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Chitturi, S., Abeygunasekera, S., Farrell, G.C., Holmes-Walker, J., Hui, J.M., Fung, C., Karim, R., Lin, R., Samarasinghe, D., Liddle, C., Weltman, M., George, J. Hepatology (2002) [Pubmed]
  4. Can clinical factors estimate insulin resistance in type 1 diabetes? Williams, K.V., Erbey, J.R., Becker, D., Arslanian, S., Orchard, T.J. Diabetes (2000) [Pubmed]
  5. Detecting glucose intolerance after gestational diabetes: inadequacy of fasting glucose alone and risk associated with gestational diabetes and second trimester waist-hip ratio. Jacob Reichelt, A.A., Ferraz, T.M., Rocha Oppermann, M.L., Costa e Forti, A., Duncan, B.B., Fleck Pessoa, E., Schmidt, M.I. Diabetologia (2002) [Pubmed]
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  10. Incidence of sleep-disordered breathing in an urban adult population: the relative importance of risk factors in the development of sleep-disordered breathing. Tishler, P.V., Larkin, E.K., Schluchter, M.D., Redline, S. JAMA (2003) [Pubmed]
  11. Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: The Hoorn Study. de Vegt, F., Dekker, J.M., Jager, A., Hienkens, E., Kostense, P.J., Stehouwer, C.D., Nijpels, G., Bouter, L.M., Heine, R.J. JAMA (2001) [Pubmed]
  12. Elevated C-reactive protein levels in overweight and obese adults. Visser, M., Bouter, L.M., McQuillan, G.M., Wener, M.H., Harris, T.B. JAMA (1999) [Pubmed]
  13. Effect of excessive weight gain with intensive therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. Diabetes Control and Complications Trial. Purnell, J.Q., Hokanson, J.E., Marcovina, S.M., Steffes, M.W., Cleary, P.A., Brunzell, J.D. JAMA (1998) [Pubmed]
  14. Fat distribution, androgens, and metabolism in nonobese women. Seidell, J.C., Cigolini, M., Deurenberg, P., Oosterlee, A., Doornbos, G. Am. J. Clin. Nutr. (1989) [Pubmed]
  15. Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver. Westerbacka, J., Yki-Järvinen, H., Vehkavaara, S., Häkkinen, A.M., Andrew, R., Wake, D.J., Seckl, J.R., Walker, B.R. J. Clin. Endocrinol. Metab. (2003) [Pubmed]
  16. Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study. Barrett-Connor, E., Ferrara, A. J. Clin. Endocrinol. Metab. (1996) [Pubmed]
  17. Responses of serum androgen and insulin resistance to metformin and pioglitazone in obese, insulin-resistant women with polycystic ovary syndrome. Ortega-González, C., Luna, S., Hernández, L., Crespo, G., Aguayo, P., Arteaga-Troncoso, G., Parra, A. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  18. Insulin resistance syndrome predicts coronary heart disease events in elderly type 2 diabetic men. Kuusisto, J., Lempiäinen, P., Mykkänen, L., Laakso, M. Diabetes Care (2001) [Pubmed]
  19. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. McKeigue, P.M., Shah, B., Marmot, M.G. Lancet (1991) [Pubmed]
  20. Linkage analysis of a composite factor for the multiple metabolic syndrome: the National Heart, Lung, and Blood Institute Family Heart Study. Tang, W., Miller, M.B., Rich, S.S., North, K.E., Pankow, J.S., Borecki, I.B., Myers, R.H., Hopkins, P.N., Leppert, M., Arnett, D.K. Diabetes (2003) [Pubmed]
  21. Multiple metabolic abnormalities in normal glucose tolerant relatives of NIDDM families. Humphriss, D.B., Stewart, M.W., Berrish, T.S., Barriocanal, L.A., Trajano, L.R., Ashworth, L.A., Brown, M.D., Miller, M., Avery, P.J., Alberti, K.G., Walker, M. Diabetologia (1997) [Pubmed]
  22. Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample. White, P.C. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  23. GH-deficient survivors of childhood cancer: GH replacement during adult life. Murray, R.D., Darzy, K.H., Gleeson, H.K., Shalet, S.M. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  24. Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism. Staiger, H., Kaltenbach, S., Staiger, K., Stefan, N., Fritsche, A., Guirguis, A., Péterfi, C., Weisser, M., Machicao, F., Stumvoll, M., Häring, H.U. Diabetes (2004) [Pubmed]
  25. Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. Berndt, J., Klöting, N., Kralisch, S., Kovacs, P., Fasshauer, M., Schön, M.R., Stumvoll, M., Blüher, M. Diabetes (2005) [Pubmed]
  26. Sex differences in visceral fat lipolysis and metabolic complications of obesity. Lönnqvist, F., Thörne, A., Large, V., Arner, P. Arterioscler. Thromb. Vasc. Biol. (1997) [Pubmed]
  27. Elevated beta2-adrenoceptor protein concentration in adipose tissue from obese subjects is closely related to the body mass index and waist/hip ratio. Rasmussen, M., Almdal, T., Bratholm, P., Christensen, N.J. Clin. Sci. (2003) [Pubmed]
  28. Searching for the biological pathways between stress and health. Kelly, S., Hertzman, C., Daniels, M. Annual review of public health. (1997) [Pubmed]
  29. Is noncentral obesity metabolically benign? Implications for prevention from a population survey. Young, T.K., Gelskey, D.E. JAMA (1995) [Pubmed]
  30. Long-term postmenopausal hormone use, obesity, and fat distribution in older women. Kritz-Silverstein, D., Barrett-Connor, E. JAMA (1996) [Pubmed]
  31. Renal function and insulin resistance as determinants of plasma leptin levels in patients with NIDDM. Shoji, T., Nishizawa, Y., Emoto, M., Maekawa, K., Hiura, Y., Tanaka, S., Kawagishi, T., Okuno, Y., Morii, H. Diabetologia (1997) [Pubmed]
  32. Growth hormone secretion among HIV infected patients: effects of gender, race and fat distribution. Koutkia, P., Eaton, K., You, S.M., Breu, J., Grinspoon, S. AIDS (2006) [Pubmed]
  33. Seasonal variation of testosterone and waist to hip ratio in men: the Tromsø study. Svartberg, J., Jorde, R., Sundsfjord, J., Bønaa, K.H., Barrett-Connor, E. J. Clin. Endocrinol. Metab. (2003) [Pubmed]
  34. Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-alpha system. Straczkowski, M., Dzienis-Straczkowska, S., Stêpieñ, A., Kowalska, I., Szelachowska, M., Kinalska, I. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  35. Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans: role of central obesity and LIPC polymorphisms. Carr, M.C., Brunzell, J.D., Deeb, S.S. J. Lipid Res. (2004) [Pubmed]
  36. Association of breast cancer risk with a common functional polymorphism (Asp327Asn) in the sex hormone-binding globulin gene. Cui, Y., Shu, X.O., Cai, Q., Jin, F., Cheng, J.R., Cai, H., Gao, Y.T., Zheng, W. Cancer Epidemiol. Biomarkers Prev. (2005) [Pubmed]
  37. Insulin-like growth factors and their binding proteins before and after weight loss and their associations with hormonal and metabolic parameters in obese adolescent girls. Wabitsch, M., Blum, W.F., Muche, R., Heinze, E., Haug, C., Mayer, H., Teller, W. Int. J. Obes. Relat. Metab. Disord. (1996) [Pubmed]
  38. The relationship of ghrelin to biochemical and anthropometric markers of adult growth hormone deficiency. Malik, I.A., English, P.J., Ghatei, M.A., Bloom, S.R., MacFarlane, I.A., Wilding, J.P. Clin. Endocrinol. (Oxf) (2004) [Pubmed]
  39. Relation of age, exercise, anthropometric measurements, and diet with glucose and insulin levels in a population aged 70 years and over. Campbell, A.J., Busby, W.J., Horwath, C.C., Robertson, M.C. Am. J. Epidemiol. (1993) [Pubmed]
  40. Association of body fat distribution and family histories of breast and ovarian cancer with risk of postmenopausal breast cancer. Sellers, T.A., Gapstur, S.M., Potter, J.D., Kushi, L.H., Bostick, R.M., Folsom, A.R. Am. J. Epidemiol. (1993) [Pubmed]
  41. Comparison of ADA and WHO criteria for the diagnosis of diabetes in elderly Koreans. Choi, K.M., Lee, J., Kim, D.R., Kim, S.K., Shin, D.H., Kim, N.H., Park, I.B., Choi, D.S., Baik, S.H. Diabet. Med. (2002) [Pubmed]
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