Chemical Compound Review:
Tyrphostin 23 2-[(3,4-dihydroxyphenyl) methylidene]propan...
Synonyms:
Tyrphostin A23, Lopac-T-7165, Tocris-0493, AG-18, CHEMBL76904, ...
- Secretoneurin, a novel neuropeptide, is a potent chemoattractant for human eosinophils. Dunzendorfer, S., Schratzberger, P., Reinisch, N., Kähler, C.M., Wiedermann, C.J. Blood (1998)
- The degree of inhibition of protein tyrosine kinase activity by tyrphostin 23 and 25 is related to their instability. Ramdas, L., McMurray, J.S., Budde, R.J. Cancer Res. (1994)
- Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90. Zhong, L., Qing, K., Si, Y., Chen, L., Tan, M., Srivastava, A. J. Biol. Chem. (2004)
- Hyaluronan synthesis by mouse cumulus cells is regulated by interactions between follicle-stimulating hormone (or epidermal growth factor) and a soluble oocyte factor (or transforming growth factor beta1). Tirone, E., D'Alessandris, C., Hascall, V.C., Siracusa, G., Salustri, A. J. Biol. Chem. (1997)
- Regulation of human T lymphocyte chemotaxis in vitro by T cell-derived cytokines IL-2, IFN-gamma, IL-4, IL-10, and IL-13. Tan, J., Deleuran, B., Gesser, B., Maare, H., Deleuran, M., Larsen, C.G., Thestrup-Pedersen, K. J. Immunol. (1995)
- Biological activity of substrate-bound basic fibroblast growth factor (FGF2): recruitment of FGF receptor-1 in endothelial cell adhesion contacts. Tanghetti, E., Ria, R., Dell'Era, P., Urbinati, C., Rusnati, M., Ennas, M.G., Presta, M. Oncogene (2002)
- Insulin-like growth factor 1 receptor-mediated endocytosis in Xenopus laevis oocytes. A role for receptor tyrosine kinase activity. Taghon, M.S., Sadler, S.E. Dev. Biol. (1994)
- Trafficking of the human transferrin receptor in plant cells: effects of tyrphostin A23 and brefeldin A. Ortiz-Zapater, E., Soriano-Ortega, E., Marcote, M.J., Ortiz-Masi??, D., Aniento, F. Plant J. (2006)
- Phagocytosis of gram-negative bacteria by a unique CD14-dependent mechanism. Schiff, D.E., Kline, L., Soldau, K., Lee, J.D., Pugin, J., Tobias, P.S., Ulevitch, R.J. J. Leukoc. Biol. (1997)
- Adrenomedullin stimulates DNA synthesis of rat adrenal zona glomerulosa cells through activation of the mitogen-activated protein kinase-dependent cascade. Semplicini, A., Ceolotto, G., Baritono, E., Malendowicz, L.K., Andreis, P.G., Sartori, M., Rossi, G.P., Nussdorfer, G.G. J. Hypertens. (2001)
- Insensitivity of cardiac delayed-rectifier I(Kr) to tyrosine phosphorylation inhibitors and stimulators. Missan, S., Zhabyeyev, P., Linsdell, P., McDonald, T.F. Br. J. Pharmacol. (2006)
- The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI. Indik, Z.K., Hunter, S., Huang, M.M., Pan, X.Q., Chien, P., Kelly, C., Levinson, A.I., Kimberly, R.P., Schreiber, A.D. Exp. Hematol. (1994)
- Oxytocin and lysophosphatidic acid induce stress fiber formation in human myometrial cells via a pathway involving Rho-kinase. Gogarten, W., Emala, C.W., Lindeman, K.S., Hirshman, C.A. Biol. Reprod. (2001)
- Growth factors mediate intracellular signaling in vascular smooth muscle cells through protein kinase C-linked pathways. Touyz, R.M., Schiffrin, E.L. Hypertension (1997)
- Protein kinase calpha but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH(2)-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1beta: involvement of sequential activation of tyrosine kinase, nuclear factor-kappaB-inducing kinase, and IkappaB kinase 2. Chen, C.C., Chen, J.J., Chou, C.Y. Mol. Pharmacol. (2000)
- Induction of c-jun protooncogene expression by hydrogen peroxide through hydroxyl radical generation and p60SRC tyrosine kinase activation. Lee, S.F., Huang, Y.T., Wu, W.S., Lin, J.K. Free Radic. Biol. Med. (1996)
- Endothelin-1[1-31], acting as an ETA-receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells. Mazzocchi, G., Rossi, G.P., Malendowicz, L.K., Champion, H.C., Nussdorfer, G.G. FEBS Lett. (2000)
- Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway. Chen, C., Chou, C., Sun, Y., Huang, W. Cell. Signal. (2001)
- Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: receptor subtype involved and signaling mechanism. Andreis, P.G., Markowska, A., Champion, H.C., Mazzocchi, G., Malendowicz, L.K., Nussdorfer, G.G. Endocrinology (2000)
- A tyrphostin-derived inhibitor of protein tyrosine kinases: isolation and characterization. Ramdas, L., Obeyesekere, N.U., McMurray, J.S., Gallick, G.E., Seifert, W.E., Budde, R.J. Arch. Biochem. Biophys. (1995)
- Tyrosine kinase inhibitor AG18 arrests follicle-stimulating hormone-induced granulosa cell differentiation: use of reverse transcriptase-polymerase chain reaction assay for multiple messenger ribonucleic acids. Orly, J., Rei, Z., Greenberg, N.M., Richards, J.S. Endocrinology (1994)
- ET(A) receptors are the primary mediators of myofilament calcium sensitization induced by ET-1 in rat pulmonary artery smooth muscle: a tyrosine kinase independent pathway. Evans, A.M., Cobban, H.J., Nixon, G.F. Br. J. Pharmacol. (1999)
- Angiotensin-II stimulates DNA synthesis in rat adrenal zona glomerulosa cells: receptor subtypes involved and possible signal transduction mechanism. Mazzocchi, G., Malendowicz, L.K., Gottardo, G., Rebuffat, P., Nussdorfer, G.G. Endocr. Res. (1997)