The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Amoscanate     N-(4-isothiocyanatophenyl)-4- nitro-aniline

Synonyms: Amoscanato, Amoscanatum, Nithiocyamine, CHEMBL93385, CCRIS 4111, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of GO 9333


High impact information on GO 9333


Chemical compound and disease context of GO 9333


Biological context of GO 9333


Anatomical context of GO 9333


Associations of GO 9333 with other chemical compounds


Analytical, diagnostic and therapeutic context of GO 9333


  1. Efficacy of amoscanate against experimental schistosomal infections in monkeys. Crawford, K.A., Asch, H.L., Bruce, J.I., Bueding, E., Smith, E.R. Am. J. Trop. Med. Hyg. (1983) [Pubmed]
  2. Clinical evaluation of amoscanate in healthy male volunteers. Shapiro, T.A., Were, J.B., Talalay, P., Bueding, E., Rocco, L., Danso, K., Massof, R., Green, R., Mellits, E.D., Lietman, P.S. Am. J. Trop. Med. Hyg. (1986) [Pubmed]
  3. Clinical trials of a new anthelmintic, 4-isothiocyanato-4'-nitrodiphenylamine (C.9333-Go/CGP 4540), for the cure of hookworm infection. Doshi, J.C., Vaidya, A.B., Sen, H.G., Mankodi, N.A., Nair, C.N., Grewal, R.S. Am. J. Trop. Med. Hyg. (1977) [Pubmed]
  4. Parasite-specific inhibition of 5'-nucleotidase from Onchocerca volvulus and Dirofilaria immitis by the amoscanate-derivative CGP 8065. Walter, R.D., Albiez, E. Mol. Biochem. Parasitol. (1985) [Pubmed]
  5. In vivo effect of benzothiazole and amoscanate derivatives on the fine structure of adult Brugia spp. and Litomosoides carinii. Franz, M., Zahner, H., Mehlhorn, H., Striebel, H.P. Parasitol. Res. (1990) [Pubmed]
  6. Protection by antibiotics against experimental focal cholangitis produced in mice by a schistosomicidal isothiocyanate. Batzinger, R.P., Bueding, E., Popper, H. Hepatology (1981) [Pubmed]
  7. Schistosomiasis drug therapy and treatment considerations. Shekhar, K.C. Drugs (1991) [Pubmed]
  8. Conversion of amoscanate to a mutagenic metabolite in gnotobiotic mice implanted with Streptococcus equinus. Reddy, B.S., Batzinger, R.P., Molineaux, C.J., Bueding, E. Antimicrob. Agents Chemother. (1982) [Pubmed]
  9. Persistence of hepatic fibrosis and tissue eggs following treatment of Schistosoma japonicum infected mice. Cheever, A.W., Deb, S. Am. J. Trop. Med. Hyg. (1989) [Pubmed]
  10. Use of the DNA-repair host-mediated assay for determining the organ distribution of genotoxic factors in mice treated orally with nitro-aromatic compounds. Knasmüller, S., Kerklaan, P., Mohn, G.R. Mutat. Res. (1986) [Pubmed]
  11. Comparison of praziquantel, amoscanate and hexachloroparaxylol in clonorchiasis sinensis. Wang, Q.N., Liu, J.B., Liu, Y.H., Chen, R.X., Qiu, Z.D., Qu, Z.Q. Chin. Med. J. (1980) [Pubmed]
  12. Hymenolepis diminuta: effects of amoscanate on energy metabolism and ultrastructure. Nelson, N.F., Saz, H.J. Exp. Parasitol. (1983) [Pubmed]
  13. The immune response to a schistosomacide, amoscanate. I. Serum antibody responses. Barton, B.E., Levy, D.A. Journal of immunopharmacology. (1985) [Pubmed]
  14. Systolic time intervals in chronic anaemia before and after 4-isothiocyanato-4'-nitrodiphenylamine (C 9333-Go/CGP 4540). A new anthelmintic. Mankodi, N.A., Vaidya, A.B., Pillay, M.G., Nargunde, H.S., Paul, T., Sheth, U.K., Kaul, C.L., Nair, K.G. The Journal of the Association of Physicians of India. (1981) [Pubmed]
  15. Electroretinographic assessment of early retinopathy in rats. Maertins, T., Kroetlinger, F., Sander, E., Pauluhn, J., Machemer, L. Arch. Toxicol. (1993) [Pubmed]
  16. Litomosoides carinii: mode of action in vitro of benzothiazole and amoscanate derivatives with antifilarial activity. Davies, K.P., Zahner, H., Köhler, P. Exp. Parasitol. (1989) [Pubmed]
  17. Schistosoma mansoni: tegumental surface alterations induced by subcurative doses of the schistosomicide amoscanate. Voge, M., Bueding, E. Exp. Parasitol. (1980) [Pubmed]
  18. Effects of amoscanate on the utilization of glucose by Brugia pahangi and Litomosoides carinii. Nelson, N.F., Saz, H.J. J. Parasitol. (1984) [Pubmed]
  19. Prevention of the mutagenic activation of an antischistosomal isothiocyanate in primates by an antibiotic. Batzinger, R.P., Bueding, E., Crawford, K., Bruce, J. Environmental mutagenesis. (1979) [Pubmed]
  20. Schistosoma haematobium: amoscanate and adult worm ultrastructure. Leitch, B., Probert, A.J. Exp. Parasitol. (1984) [Pubmed]
  21. Detectability and measurability of amoscanate in plasma by TLC and HPLC. Kofi-Tsekpo, W.M., Karekezi, C.W. Drugs under experimental and clinical research. (1988) [Pubmed]
  22. Histological changes elicited in Schistosoma japonicum infected rabbits following curative chemotherapy with 4-isothiocyano-4'-nitro-diphenylamine (C9333-Go/CGP 4540). Robinson, A., Lewert, R.M. Trans. R. Soc. Trop. Med. Hyg. (1981) [Pubmed]
WikiGenes - Universities