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Chemical Compound Review

Strontium Radioisotopes     strontium

Synonyms: Strontium-90, AC1NUOFQ, Sr-90, HSDB 7403, D013326000, ...
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Disease relevance of strontium

  • A retrospective evaluation was performed with records of 128 patients with 146 eyes that underwent applications of strontium-90 after pterygium excisions performed between 1982 and 1988 [1].
  • Adjunctive radiotherapy with strontium-90 in the treatment of conjunctival squamous cell carcinoma [2].
  • PATIENTS AND METHODS: 83 keloids of 66 patients had been irradiated after excision by a uniform protocol with 4 x 5 Gy (strontium- 90 [(90)Sr] surface applicator) [3].
  • Of 140 patients with histologically confirmed squamous cell cancer, 123 were treated with a strontium-90 source, 10 with a radon "ring," and 7 with superficial X ray therapy [2].
  • Late toxicities that may be associated with strontium-90 RT were scleromalacia (scleral thinning) in 4 eyes, adhesion of eyelids in 3 eyes, and scleral ulcer in 2 eyes [4].

High impact information on strontium


Chemical compound and disease context of strontium


Biological context of strontium


Anatomical context of strontium


Gene context of strontium


Analytical, diagnostic and therapeutic context of strontium


  1. Pterygia: single-fraction postoperative beta irradiation. Beyer, D.C. Radiology. (1991) [Pubmed]
  2. Adjunctive radiotherapy with strontium-90 in the treatment of conjunctival squamous cell carcinoma. Kearsley, J.H., Fitchew, R.S., Taylor, R.G. Int. J. Radiat. Oncol. Biol. Phys. (1988) [Pubmed]
  3. Results of postoperative (90)Sr radiotherapy of keloids in view of patients' subjective assessment. Fraunholz, I.B., Gerstenhauer, A., Böttcher, H.D. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]. (2005) [Pubmed]
  4. Long-term results of fractionated strontium-90 radiation therapy for pterygia. Nishimura, Y., Nakai, A., Yoshimasu, T., Yagyu, Y., Nakamatsu, K., Shindo, H., Ishida, O. Int. J. Radiat. Oncol. Biol. Phys. (2000) [Pubmed]
  5. Radioactivity measurements of former military personnel exposed to weapon debris. Toohey, R.E., Rundo, J., Essling, M.A., Sha, J.Y., Oldham, R.D., Sedlet, J., Robinson, J.J. Science (1981) [Pubmed]
  6. Relationship of success in classical immunotherapy to the relative immunorejective strength of the tumor. Reif, A.E. J. Natl. Cancer Inst. (1986) [Pubmed]
  7. The use of confocal scanning laser tomography in the evaluation of retinal elevation in age-related macular degeneration. Jaakkola, A., Vesti, E., Immonen, I. Ophthalmology (1999) [Pubmed]
  8. Hyperbaric oxygen therapy for beta-radiation-induced scleral necrosis. Green, M.O., Brannen, A.L. Ophthalmology (1995) [Pubmed]
  9. Mice treated with strontium 90: an animal model deficient in NK cells. Emmanuel, F.X., Vaughan, A.T., Catty, D. Br. J. Cancer (1981) [Pubmed]
  10. Three-year clinical follow-up after strontium-90/yttrium-90 beta-irradiation for the treatment of in-stent coronary restenosis. Baierl, V., Baumgartner, S., Pöllinger, B., Leibig, M., Rieber, J., König, A., Krötz, F., Sohn, H.Y., Siebert, U., Haimerl, W., Dühmke, E., Theisen, K., Klauss, V., Schiele, T.M. Am. J. Cardiol. (2005) [Pubmed]
  11. Correlation between Octopus perimetry and fluorescein angiography after strontium-90 plaque brachytherapy for subfoveal exudative age related macular degeneration. Jaakkola, A., Vesti, E., Immonen, I. The British journal of ophthalmology. (1998) [Pubmed]
  12. The effect of beta irradiation on monkey Tenon's capsule fibroblasts in tissue culture. Nevárez, J.A., Parrish, R.K., Heuer, D.K., Hajek, A.S., Houdek, P.V., Mallick, K.S. Curr. Eye Res. (1987) [Pubmed]
  13. Nuclear fallout, low birthweight, and immune deficiency. Gould, J.M., Sternglass, E.J. International journal of health services : planning, administration, evaluation. (1994) [Pubmed]
  14. Genetic damage in a population of slider turtles (Trachemys scripta) inhabiting a radioactive reservoir. Lamb, T., Bickham, J.W., Gibbons, J.W., Smolen, M.J., McDowell, S. Arch. Environ. Contam. Toxicol. (1991) [Pubmed]
  15. 18 years' experience with high dose rate strontium-90 brachytherapy of small to medium sized posterior uveal melanoma. van Ginderdeuren, R., van Limbergen, E., Spileers, W. The British journal of ophthalmology. (2005) [Pubmed]
  16. Splenic thrombopoiesis after bone marrow ablation with radiostrontium: a murine model. Davis, E., Corash, L., Baker, G., Mok, Y., Hill, R.J., Levin, J. J. Lab. Clin. Med. (1990) [Pubmed]
  17. Strontium-90 in deciduous teeth as a factor in early childhood cancer. Gould, J.M., Sternglass, E.J., Sherman, J.D., Brown, J., McDonnell, W., Mangano, J.J. International journal of health services : planning, administration, evaluation. (2000) [Pubmed]
  18. Histologic studies of splenic megakaryocytes after bone marrow ablation with strontium 90. Davis, E., Corash, L., Stenberg, P., Levin, J. J. Lab. Clin. Med. (1992) [Pubmed]
  19. Evaluation of strontium 90 irradiation in treatment of cutaneous mast cell tumors in cats: 35 cases (1992-2002). Turrel, J.M., Farrelly, J., Page, R.L., McEntee, M.C. J. Am. Vet. Med. Assoc. (2006) [Pubmed]
  20. Effect of beta radiation on proliferating human Tenon's capsule fibroblasts. Khaw, P.T., Ward, S., Grierson, I., Rice, N.S. The British journal of ophthalmology. (1991) [Pubmed]
  21. Results of histo-pathologic examination of three enucleated eyes with a choroidal melanoma after strontium-90 irradiation. Parys-van Ginderdeuren, R., van den Oord, J.J., Missotten, L. Bulletin de la Société belge d'ophtalmologie. (1997) [Pubmed]
  22. beta Dose distribution during beta irradiation using strontium-90 in ophthalmic practice. Hegazy, M.A., Ayad, A., El-Haddad, S.I., Mahfouz, M.M. Bulletin of the Ophthalmological Society of Egypt. (1978) [Pubmed]
  23. Vaccination against strontium-90-induced bone tumors. Reif, A.E., Triest, W.E. J. Natl. Cancer Inst. (1983) [Pubmed]
  24. Results of treatment of choroidal malignant melanoma with high-dose-rate strontium-90 brachytherapy. A retrospective study of 46 patients treated between 1983 and 1995. Missotten, L., Dirven, W., Van der Schueren, A., Leys, A., De Meester, G., Van Limbergen, E. Graefes Arch. Clin. Exp. Ophthalmol. (1998) [Pubmed]
  25. Beta-radiation for coronary in-stent restenosis. Latchem, D.R., Urban, P., Goy, J.J., De Benedetti, E., Pica, A., Coucke, P., Eeckhout, E. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. (2000) [Pubmed]
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