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MeSH Review

Live Birth

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Disease relevance of Live Birth


Psychiatry related information on Live Birth


High impact information on Live Birth

  • CONCLUSIONS: Treating women who have autoantibodies and recurrent fetal loss with prednisone and aspirin is not effective in promoting live birth, and it increases the risk of prematurity [8].
  • Among DES-exposed women who became pregnant, 81 per cent had at least one full-term live birth [9].
  • Analysis of 164 live births from AQP4[+/-] matings showed 41 [+/+], 83 [+/-], and 40 [-/-] genotypes [10].
  • Craniosynostosis, the premature fusion of the bones of the skull, is a common birth defect (1 in 3000 live births) that disrupts coordinate growth and often results in profoundly abnormal skull shape [11].
  • Cases and controls came from two longitudinal populations, the Child Health and Development Studies (CHDS) and the national Collaborative Perinatal Project (CPP), together comprising more than 70,000 live births [12].

Chemical compound and disease context of Live Birth


Biological context of Live Birth


Anatomical context of Live Birth


Associations of Live Birth with chemical compounds


Gene context of Live Birth


Analytical, diagnostic and therapeutic context of Live Birth

  • The adjusted risk of secondary tubal infertility associated with use of a copper IUD after a first live birth was not statistically significant (1.5; 95 per cent confidence limits, 0.8 to 3.0), whereas the risk from similar use of noncopper devices was significant (2.8; 1.3 to 5.9) [1].
  • PURPOSE: This study was undertaken to determine the effect, if any, of prior treatment with radiation therapy or chemotherapy for Wilms tumor diagnosed during childhood or adolescence on live births, birthweight, and the frequency of congenital malformations [37].
  • METHOD: A retrospective cohort study of all live births to 209 incident patients with epilepsy in Iceland from 1960 to 1964 and live births to 418 age- (to the closest day of birth) and gender-matched residents without epilepsy [38].
  • The frequency of adverse events (AE) during pregnancy in the women with epilepsy is similar to that observed among all live births in the population, but cesarean section was performed twice as frequently as in the general population [39].
  • CONCLUSION: Egg-sharing does not compromise the chance of achieving a pregnancy or live birth for the egg-sharer or the recipient as compared to standard IVF/ICSI patients [40].


  1. Tubal infertility and the intrauterine device. Cramer, D.W., Schiff, I., Schoenbaum, S.C., Gibson, M., Belisle, S., Albrecht, B., Stillman, R.J., Berger, M.J., Wilson, E., Stadel, B.V. N. Engl. J. Med. (1985) [Pubmed]
  2. Germline mutations of the RET ligand GDNF are not sufficient to cause Hirschsprung disease. Salomon, R., Attié, T., Pelet, A., Bidaud, C., Eng, C., Amiel, J., Sarnacki, S., Goulet, O., Ricour, C., Nihoul-Fékété, C., Munnich, A., Lyonnet, S. Nat. Genet. (1996) [Pubmed]
  3. Localization of cystic fibrosis locus to human chromosome 7cen-q22. Wainwright, B.J., Scambler, P.J., Schmidtke, J., Watson, E.A., Law, H.Y., Farrall, M., Cooke, H.J., Eiberg, H., Williamson, R. Nature (1985) [Pubmed]
  4. Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk. Xie, D., Shu, X.O., Deng, Z., Wen, W.Q., Creek, K.E., Dai, Q., Gao, Y.T., Jin, F., Zheng, W. J. Natl. Cancer Inst. (2000) [Pubmed]
  5. Differences in breast cancer risk factors according to the estrogen receptor level of the tumor. Hildreth, N.G., Kelsey, J.L., Eisenfeld, A.J., LiVolsi, V.A., Holford, T.R., Fischer, D.B. J. Natl. Cancer Inst. (1983) [Pubmed]
  6. Long-term effects of fluoxetine or vehicle administration during pregnancy on behavioral outcomes in guinea pig offspring. Vartazarmian, R., Malik, S., Baker, G.B., Boksa, P. Psychopharmacology (Berl.) (2005) [Pubmed]
  7. The association of body fat distribution with lifestyle and reproductive factors in a population study of postmenopausal women. Kaye, S.A., Folsom, A.R., Prineas, R.J., Potter, J.D., Gapstur, S.M. International journal of obesity. (1990) [Pubmed]
  8. Prednisone and aspirin in women with autoantibodies and unexplained recurrent fetal loss. Laskin, C.A., Bombardier, C., Hannah, M.E., Mandel, F.P., Ritchie, J.W., Farewell, V., Farine, D., Spitzer, K., Fielding, L., Soloninka, C.A., Yeung, M. N. Engl. J. Med. (1997) [Pubmed]
  9. Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol. Barnes, A.B., Colton, T., Gundersen, J., Noller, K.L., Tilley, B.C., Strama, T., Townsend, D.E., Hatab, P., O'Brien, P.C. N. Engl. J. Med. (1980) [Pubmed]
  10. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. Ma, T., Yang, B., Gillespie, A., Carlson, E.J., Epstein, C.J., Verkman, A.S. J. Clin. Invest. (1997) [Pubmed]
  11. Premature suture closure and ectopic cranial bone in mice expressing Msx2 transgenes in the developing skull. Liu, Y.H., Kundu, R., Wu, L., Luo, W., Ignelzi, M.A., Snead, M.L., Maxson, R.E. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  12. Thyroid antibodies as a risk factor for Down syndrome and other trisomies. Torfs, C.P., van den Berg, B.J., Oechsli, F.W., Christianson, R.E. Am. J. Hum. Genet. (1990) [Pubmed]
  13. Characterization of a putative founder mutation that accounts for the high incidence of cystinosis in Brittany. Kalatzis, V., Cherqui, S., Jean, G., Cordier, B., Cochat, P., Broyer, M., Antignac, C. J. Am. Soc. Nephrol. (2001) [Pubmed]
  14. Questions about dexamethasone use for the prevention of anti-SSA related congenital heart block. Costedoat-Chalumeau, N., Amoura, Z., Le Thi Hong, D., Wechsler, B., Vauthier, D., Ghillani, P., Papo, T., Fain, O., Musset, L., Piette, J.C. Ann. Rheum. Dis. (2003) [Pubmed]
  15. Pregnancy complications in women with recurrent miscarriage associated with antiphospholipid antibodies treated with low dose aspirin and heparin. Backos, M., Rai, R., Baxter, N., Chilcott, I.T., Cohen, H., Regan, L. British journal of obstetrics and gynaecology. (1999) [Pubmed]
  16. The cost of infertility diagnosis and treatment in Canada in 1995. Collins, J.A., Feeny, D., Gunby, J. Hum. Reprod. (1997) [Pubmed]
  17. Vaginal misoprostol versus concentrated oxytocin and vaginal PGE2 for second-trimester labor induction. Ramsey, P.S., Savage, K., Lincoln, T., Owen, J. Obstetrics and gynecology. (2004) [Pubmed]
  18. Rescue of female infertility from the loss of cyclooxygenase-2 by compensatory up-regulation of cyclooxygenase-1 is a function of genetic makeup. Wang, H., Ma, W.G., Tejada, L., Zhang, H., Morrow, J.D., Das, S.K., Dey, S.K. J. Biol. Chem. (2004) [Pubmed]
  19. Caffeine consumption during pregnancy and fetal growth. Fenster, L., Eskenazi, B., Windham, G.C., Swan, S.H. American journal of public health. (1991) [Pubmed]
  20. A prospective study of the effects of female and male caffeine consumption on the reproductive endpoints of IVF and gamete intra-Fallopian transfer. Klonoff-Cohen, H., Bleha, J., Lam-Kruglick, P. Hum. Reprod. (2002) [Pubmed]
  21. Stimulated intra-uterine insemination is not a natural choice for the treatment of unexplained subfertility. 'Effective treatment' or 'not a natural choice'? Hughes, E.G. Hum. Reprod. (2003) [Pubmed]
  22. Oocyte number per live birth in IVF: were Steptoe and Edwards less wasteful? Inge, G.B., Brinsden, P.R., Elder, K.T. Hum. Reprod. (2005) [Pubmed]
  23. Use of Synthetic Serum Substitute and alpha-minimum essential medium for the extended culture of human embryos to the blastocyst stage. Desai, N., Kinzer, D., Loeb, A., Goldfarb, J. Hum. Reprod. (1997) [Pubmed]
  24. An estrogen receptor genetic polymorphism and the risk of primary and secondary recurrent spontaneous abortion. Berkowitz, G.S., Stone, J.L., Lehrer, S.P., Marcus, M., Lapinski, R.H., Schachter, B.S. Am. J. Obstet. Gynecol. (1994) [Pubmed]
  25. Oviduct prostacyclin functions as a paracrine factor to augment the development of embryos. Huang, J.C., Goldsby, J.S., Arbab, F., Melhem, Z., Aleksic, N., Wu, K.K. Hum. Reprod. (2004) [Pubmed]
  26. Interaction fallacy. Morabia, A., Ten Have, T., Landis, J.R. Journal of clinical epidemiology. (1997) [Pubmed]
  27. Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder. Gris, J.C., Mercier, E., Quéré, I., Lavigne-Lissalde, G., Cochery-Nouvellon, E., Hoffet, M., Ripart-Neveu, S., Tailland, M.L., Dauzat, M., Marès, P. Blood (2004) [Pubmed]
  28. Effects of childbearing on glucose tolerance and NIDDM prevalence. Boyko, E.J., Alderman, B.W., Keane, E.M., Baron, A.E. Diabetes Care (1990) [Pubmed]
  29. Pregnancy outcome after cyclosporine therapy during pregnancy: a meta-analysis. Bar Oz, B., Hackman, R., Einarson, T., Koren, G. Transplantation (2001) [Pubmed]
  30. Potential therapeutic effects of contrast materials in hysterosalpingography: a prospective randomized clinical trial. Kaiser Permanente Infertility Work Group. Spring, D.B., Barkan, H.E., Pruyn, S.C. Radiology. (2000) [Pubmed]
  31. Relationships of age and reproductive characteristics with plasma estrogens and androgens in premenopausal women. Dorgan, J.F., Reichman, M.E., Judd, J.T., Brown, C., Longcope, C., Schatzkin, A., Campbell, W.S., Franz, C., Kahle, L., Taylor, P.R. Cancer Epidemiol. Biomarkers Prev. (1995) [Pubmed]
  32. Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history. Rebbeck, T.R., Wang, Y., Kantoff, P.W., Krithivas, K., Neuhausen, S.L., Godwin, A.K., Daly, M.B., Narod, S.A., Brunet, J.S., Vesprini, D., Garber, J.E., Lynch, H.T., Weber, B.L., Brown, M. Cancer Res. (2001) [Pubmed]
  33. A spectrum of mutations in the polycystic kidney disease-2 (PKD2) gene from eight Canadian kindreds. Pei, Y., He, N., Wang, K., Kasenda, M., Paterson, A.D., Chan, G., Liang, Y., Roscoe, J., Brissenden, J., Hefferton, D., Parfrey, P., Somlo, S., St George-Hyslop, P. J. Am. Soc. Nephrol. (1998) [Pubmed]
  34. Down's syndrome and celiac disease. Zubillaga, P., Vitoria, J.C., Arrieta, A., Echaniz, P., Garcia-Masdevall, M.D. J. Pediatr. Gastroenterol. Nutr. (1993) [Pubmed]
  35. Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress. Paradisi, M., McClintock, D., Boguslavsky, R.L., Pedicelli, C., Worman, H.J., Djabali, K. BMC Cell Biol. (2005) [Pubmed]
  36. Metachromatic leukodystrophy: identification of the first deletion in exon 1 and of nine novel point mutations in the arylsulfatase A gene. Draghia, R., Letourneur, F., Drugan, C., Manicom, J., Blanchot, C., Kahn, A., Poenaru, L., Caillaud, C. Hum. Mutat. (1997) [Pubmed]
  37. Pregnancy outcome after treatment for Wilms tumor: a report from the National Wilms Tumor Study Group. Green, D.M., Peabody, E.M., Nan, B., Peterson, S., Kalapurakal, J.A., Breslow, N.E. J. Clin. Oncol. (2002) [Pubmed]
  38. Fertility in patients with epilepsy: a population-based study. Olafsson, E., Hauser, W.A., Gudmundsson, G. Neurology (1998) [Pubmed]
  39. Pregnancies of women with epilepsy: a population-based study in Iceland. Olafsson, E., Hallgrimsson, J.T., Hauser, W.A., Ludvigsson, P., Gudmundsson, G. Epilepsia (1998) [Pubmed]
  40. Does egg-sharing compromise the chance of donors or recipients achieving a live birth? Thum, M.Y., Gafar, A., Wren, M., Faris, R., Ogunyemi, B., Korea, L., Scott, L., Abdalla, H.I. Hum. Reprod. (2003) [Pubmed]
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