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Disease relevance of Pterygium


Psychiatry related information on Pterygium


High impact information on Pterygium


Chemical compound and disease context of Pterygium

  • A retrospective evaluation was performed with records of 128 patients with 146 eyes that underwent applications of strontium-90 after pterygium excisions performed between 1982 and 1988 [10].
  • PURPOSE: There is now increasing evidence that pterygium and pinguecula are tumorlike tissues and that cell growth and DNA replication are closely linked to cholesterol metabolism [11].
  • A Purtscher-like retinopathy occurred in a 41-year-old woman who underwent the excision of a pterygium after a retrobulbar injection of 3 ml of lidocaine HCl [12].
  • Of 1102 consecutive patients treated with beta irradiation after pterygium removal at the Queensland Radium Institute from 1973 through 1978, 503 had a follow-up ophthalmologic examination in 1989, while a further 82 had at least a 10-year follow-up from ophthalmologic records [13].
  • Inefficacy of low-dose intraoperative fluorouracil in the treatment of primary pterygium [14].

Biological context of Pterygium


Anatomical context of Pterygium


Gene context of Pterygium


Analytical, diagnostic and therapeutic context of Pterygium


  1. Amniotic membrane transplantation for reconstruction of the conjunctival fornices. Solomon, A., Espana, E.M., Tseng, S.C. Ophthalmology (2003) [Pubmed]
  2. Distribution of TFF peptides in corneal disease and pterygium. Steven, P., Schäfer, G., Nölle, B., Hinz, M., Hoffmann, W., Paulsen, F. Peptides (2004) [Pubmed]
  3. The treatment of Pseudomonas keratoscleritis after pterygium excision. Huang, S.C., Lai, H.C., Lai, I.C. Cornea (1999) [Pubmed]
  4. Topical indomethacin solution versus dexamethasone solution for treatment of inflamed pterygium and pinguecula: a prospective randomized clinical study. Frucht-Pery, J., Siganos, C.S., Solomon, A., Shvartzenberg, T., Richard, C., Trinquand, C. Am. J. Ophthalmol. (1999) [Pubmed]
  5. Pterygium/pinguecula and the five-year incidence of age-related maculopathy. Pham, T.Q., Wang, J.J., Rochtchina, E., Mitchell, P. Am. J. Ophthalmol. (2005) [Pubmed]
  6. Efficacy of lidocaine 2% gel in pterygium surgery. Oksuz, H., Tamer, C. Acta ophthalmologica Scandinavica. (2005) [Pubmed]
  7. The 18p- syndrome. Report of five cases. Zumel, R.M., Darnaude, M.T., Delicado, A., Diaz de Bustamante, A., de Torres, M.L., López-Pájares, I. Ann. Genet. (1989) [Pubmed]
  8. Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Kondo, S., Schutte, B.C., Richardson, R.J., Bjork, B.C., Knight, A.S., Watanabe, Y., Howard, E., de Lima, R.L., Daack-Hirsch, S., Sander, A., McDonald-McGinn, D.M., Zackai, E.H., Lammer, E.J., Aylsworth, A.S., Ardinger, H.H., Lidral, A.C., Pober, B.R., Moreno, L., Arcos-Burgos, M., Valencia, C., Houdayer, C., Bahuau, M., Moretti-Ferreira, D., Richieri-Costa, A., Dixon, M.J., Murray, J.C. Nat. Genet. (2002) [Pubmed]
  9. The role of ultraviolet irradiation and heparin-binding epidermal growth factor-like growth factor in the pathogenesis of pterygium. Nolan, T.M., DiGirolamo, N., Sachdev, N.H., Hampartzoumian, T., Coroneo, M.T., Wakefield, D. Am. J. Pathol. (2003) [Pubmed]
  10. Pterygia: single-fraction postoperative beta irradiation. Beyer, D.C. Radiology. (1991) [Pubmed]
  11. Hyperexpression of low-density lipoprotein receptors and hydroxy-methylglutaryl-coenzyme A-reductase in human pinguecula and primary pterygium. Peiretti, E., Dessì, S., Putzolu, M., Fossarello, M. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  12. Purtscher-like retinopathy after retrobulbar anesthesia. Lemagne, J.M., Michiels, X., Van Causenbroeck, S., Snyers, B. Ophthalmology (1990) [Pubmed]
  13. Recurrence rate and complications after beta irradiation for pterygia. MacKenzie, F.D., Hirst, L.W., Kynaston, B., Bain, C. Ophthalmology (1991) [Pubmed]
  14. Inefficacy of low-dose intraoperative fluorouracil in the treatment of primary pterygium. Maldonado, M.J., Cano-Parra, J., Navea-Tejerina, A., Cisneros, A.L., Vila, E., Menezo, J.L. Arch. Ophthalmol. (1995) [Pubmed]
  15. Lip pits and deletion 1q32----41. Bocian, M., Walker, A.P. Am. J. Med. Genet. (1987) [Pubmed]
  16. Null type of glutathione S-transferase M1 polymorphism is associated with early onset pterygium. Tsai, Y.Y., Lee, H., Tseng, S.H., Cheng, Y.W., Tsai, C.H., Wu, Y.H., Tsai, F.J. Mol. Vis. (2004) [Pubmed]
  17. Loss of heterozygosity and p53 expression in Pterygium. Reisman, D., McFadden, J.W., Lu, G. Cancer Lett. (2004) [Pubmed]
  18. Genetic polymorphism of hOGG1 and risk of pterygium in Chinese. Kau, H.C., Tsai, C.C., Hsu, W.M., Liu, J.H., Wei, Y.H. Eye (London, England) (2004) [Pubmed]
  19. Expression of p53 protein in pterygium. Onur, C., Orhan, D., Orhan, M., Dizbay Sak, S., Tulunay, O., Irkeç, M. European journal of ophthalmology. (1998) [Pubmed]
  20. Overexpression of Insulin-like growth factor-binding protein-2 in pterygium body fibroblasts. Solomon, A., Grueterich, M., Li, D.Q., Meller, D., Lee, S.B., Tseng, S.C. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  21. Outcome of nonimmune hydrops fetalis diagnosed during the first half of pregnancy. Iskaros, J., Jauniaux, E., Rodeck, C. Obstetrics and gynecology. (1997) [Pubmed]
  22. Lectin-cytochemical study on epithelial mucus glycoprotein of conjunctiva and pterygium. Kawano, K., Uehara, F., Ohba, N. Exp. Eye Res. (1988) [Pubmed]
  23. Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells. Dushku, N., John, M.K., Schultz, G.S., Reid, T.W. Arch. Ophthalmol. (2001) [Pubmed]
  24. Expression of vascular endothelial growth factor and inducible nitric oxide synthase in pterygia. Lee, D.H., Cho, H.J., Kim, J.T., Choi, J.S., Joo, C.K. Cornea (2001) [Pubmed]
  25. Connective tissue growth factor in pterygium: simultaneous presence with vascular endothelial growth factor - possible contributing factor to conjunctival scarring. van Setten, G., Aspiotis, M., Blalock, T.D., Grotendorst, G., Schultz, G. Graefes Arch. Clin. Exp. Ophthalmol. (2003) [Pubmed]
  26. Growth factors in cultured pterygium fibroblasts: immunohistochemical and ELISA analysis. Kria, L., Ohira, A., Amemiya, T. Graefes Arch. Clin. Exp. Ophthalmol. (1998) [Pubmed]
  27. Microarray and protein analysis of human pterygium. John-Aryankalayil, M., Dushku, N., Jaworski, C.J., Cox, C.A., Schultz, G., Smith, J.A., Ramsey, K.E., Stephan, D.A., Freedman, K.A., Reid, T.W., Carper, D.A. Mol. Vis. (2006) [Pubmed]
  28. Variable expression of the popliteal pterygium syndrome in two 3-generation families. Soekarman, D., Cobben, J.M., Vogels, A., Spauwen, P.H., Fryns, J.P. Clin. Genet. (1995) [Pubmed]
  29. Anterior segment indocyanine green angiography in pterygium surgery with conjunctival autograft transplantation. Tayanc, E., Akova, Y., Yilmaz, G., Aydin, P. Am. J. Ophthalmol. (2003) [Pubmed]
  30. Cell cycle kinetics in pterygium at three latitudes. Karukonda, S.R., Thompson, H.W., Beuerman, R.W., Lam, D.S., Wilson, R., Chew, S.J., Steinemann, T.L. The British journal of ophthalmology. (1995) [Pubmed]
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