Disease relevance of Technetium-99-HMPAO

• Detection of inflammatory bowel disease in pediatric patients with technetium-99m-HMPAO-labeled leukocytes [1].
• Technetium-99m-HMPAO brain SPECT, with hyperventilation challenge, was performed to assess cerebral vascular reserve since the stress of hyperventilation was thought likely to rehearse that of labor [2].
• Technetium-99m-HMPAO SPECT in Sturge-Weber syndrome [3].
• Discordance between FDG uptake and technetium-99m-HMPAO brain perfusion in acute traumatic brain injury [4].
• Spread of infectious complications of odontogenic abscess detected by technetium-99m-HMPAO-labeled WBC scan of occult sepsis in the intensive care unit [5].

Psychiatry related information on Technetium-99-HMPAO

• High-resolution technetium-99m-HMPAO SPECT in patients with probable Alzheimer's disease: comparison with fluorine-18-FDG PET [6].
• Technetium-99m-HMPAO in Tourette's syndrome on neuroleptic therapy and after withdrawal [7].
• Functional deficits in autistic disorder: characterization by technetium-99m-HMPAO and SPECT [8].
• Technetium-99m-HMPAO brain SPECT in anorexia nervosa [9].
• Technetium-99m-HMPAO SPECT imaging of cerebral blood flow during REM sleep in narcoleptics [10].

High impact information on Technetium-99-HMPAO

• This study describes a method for quantifying cerebral blood flow (CBF) distribution in Alzheimer's disease (AD) from SPECT images obtained with (99m)Tc-hexamethylpropyleneamine oxime (HMPAO) by 3-dimensional fractal analysis (3D-FA) [11].
• Regional cerebral blood flow was evaluated by (99m)Tc-hexamethylpropyleneamine oxime SPECT in 7 patients (age range, 7--18 y; mean age, 9.1 y) affected with Behçet's disease and signs or symptoms of central nervous system involvement at different times of their clinical history [12].
• Clinical usefulness of technetium-99m-HMPAO-labeled leukocyte scan in prosthetic vascular graft infection [13].
• Technetium-99m-HMPAO brain SPECT in systemic lupus erythematosus with central nervous system involvement [14].
• Technetium-99m-HMPAO white blood cell (WBC) imaging of widespread myositis [15].

Chemical compound and disease context of Technetium-99-HMPAO

• Extracranial metastatic glioblastoma: appearance on thallium-201-chloride/technetium-99m-HMPAO SPECT images [16].
• Thallium-201 appears to be a promising radiopharmaceutical for differentiating high- and low-grade gliomas, whereas Technetium-99m-HMPAO is not [17].

Biological context of Technetium-99-HMPAO

• Functional upregulation of granulocytes labeled with technetium-99m-HMPAO and indium-111-oxinate [18].
• Relationship of decreased chemotaxis of technetium-99m-HMPAO-labeled lymphocytes to apoptosis [19].
• Alveolar integrity in pulmonary emphysema using technetium-99m-DTPA and technetium-99m-HMPAO radioaerosol inhalation lung scintigraphy [20].
• Hyperventilation technetium-99m-HMPAO brain SPECT in moyamoya disease to assess risk of natural childbirth [2].

Anatomical context of Technetium-99-HMPAO

• Intra-individual differences between technetium-99m-HMPAO and technetium-99m-ECD in the normal medial temporal lobe [21].
• Technetium-99m-HMPAO uptake was decreased intracranially in the right frontal and parietal lobes which had been irradiated [16].
• Reversible hypoperfusion of the cerebral cortex in normal-pressure hydrocephalus on technetium-99m-HMPAO brain SPECT images after shunt operation [22].
• Lacrimal gland dosimetry for the brain imaging agent technetium-99m-HMPAO [23].
• Visual stimulation increases technetium-99m-HMPAO distribution in human visual cortex [24].

Associations of Technetium-99-HMPAO with other chemical compounds

• Computer-assisted superimposition of magnetic resonance and high-resolution technetium-99m-HMPAO and thallium-201 SPECT images of the brain [25].
• Technetium-99m-HMPAO-labeled leukocytes and technetium-99m-labeled human polyclonal immunoglobulin G in diagnosis of focal purulent disease [26].
• Brain perfusion is abnormal in cocaine-dependent polydrug users: a study using technetium-99m-HMPAO and ASPECT [27].
• Cobalt-57 and technetium-99m-HMPAO-labeled leukocytes for visualization of ischemic infarcts [28].
• Comparison of technetium-99m-HMPAO and xenon-133 measurements of regional cerebral blood flow by SPECT [29].

Gene context of Technetium-99-HMPAO

• Difference images calculated from ictal and interictal technetium-99m-HMPAO SPECT scans of epilepsy [30].
• Technetium-99m-HMPAO SPECT cerebral blood flow study in children with craniosynostosis [31].
• Inflammatory bowel disease activity assessment using technetium-99m-HMPAO leukocytes [32].

Analytical, diagnostic and therapeutic context of Technetium-99-HMPAO

• METHODS: The severity of AD was measured with the Cognitive Ability Screening Instrument (age and education adjusted). rCBF was assessed using (99m)Tc-hexamethylpropyleneamine oxime brain SPECT; differences in rCBF between groups with different educational levels were determined using statistical parametric mapping (SPM) [33].
• Technetium-99m-HMPAO can be used to evaluate abnormal brain perfusion in the hyperacute stage of stroke [34].
• Technetium-99m-HMPAO brain SPECT and x-ray-CT scans were acquired [35].
• Evolution of technetium-99m-HMPAO SPECT and brain mapping in a patient presenting with echolalia and palilalia [36].
• The usefulness of the 1-hour technetium-99m-HMPAO leukocyte scan in the early diagnosis of acute abdominal sepsis [37].

References