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Chemical Compound Review

SureCN54123     (2R,3S,4S,5R)-2- (hydroxymethyl)-6-octoxy...

Synonyms: AG-F-89671, AC1L1WFS, CTK8G2135, FT-0640257, 30887_FLUKA, ...
 
 
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Disease relevance of Octyl glucoside

 

High impact information on Octyl glucoside

  • Although each fraction by itself was inactive, recombining them resulted in complete recovery of the original ability of native cytosol to support SDS-elicited superoxide production by octyl-glucoside solubilized macrophage membranes [6].
  • PM InsP3R-L of Pam cells was hardly extracted by treatment with 0.5% Triton X-100 or 60 mM octyl-glucoside in a cytoskeleton-stabilizing buffer for 15 minutes at 4 degrees C. The results show that the distribution of caveolae bearing PM InsP3R-L changes when the actin cytoskeleton is modified [7].
  • Thirty-five millimolar octyl glucoside (OG) extracted 75% of these membranes from the Triton X-100-resistant pellet [8].
  • The saponin octyl-D-glucopyranoside had no effect on the LPS-induced expression of E-selectin and VCAM-1 excluding an unspecific detergent-like effect of AS-IV [9].
  • In POPC/OG mixed micelles, the even-numbered residues facing the hydrocarbon show an increased mobility compared with the bilayer environment whereas the inward-facing side chains show little change in motion [10].
 

Chemical compound and disease context of Octyl glucoside

 

Anatomical context of Octyl glucoside

  • METHODS: The distribution of intracellular IL-5 in human peripheral blood eosinophils (PBE) and lymphocytes (PBL) has been investigated using fixation and cell membrane permeabilization with octyl-glucopyranoside, the FOG-method, and flow cytometry [12].
  • The cytoskeleton retained nearly 70% of the external JV envelope glycoprotein GP38 and about 40% of the JV nucleoprotein NP, according to TX-100 and OG insolubility results [11].
  • The addition of sodium sulfate to a myelin suspension in sodium phosphate buffer at neutral pH, containing octyl glucoside detergent (OG), increases the membrane solubility more than 5-fold by an unknown structural mechanism [13].
  • Rb. capsulatus MW442 (B800-850- B875+ car+) chromatophores were extracted with benzene and titrated with octyl glucoside (OG) to shift the near-infrared absorption maximum from 873 to 816 nm [14].
  • At present the octyl-glucoside reconstituted monooxygenase system seems to be the most appropriate model for studying protein-protein and protein-lipid interactions in liver microsomes due to the similarity with respect to the main structural and functional properties, including size [15].
 

Associations of Octyl glucoside with other chemical compounds

  • A fast step in the range of 10 ms was detected regardless of whether the reaction mixture contained pigments or proteins, or both, and is interpreted as being connected with the formation of mixed SDS and OG detergent micelles [16].
  • Our results show that while M protein acquired resistance to both TX-100 and OG extraction, F and HN exhibited insolubility only to TX-100 but not to OG [17].
 

Gene context of Octyl glucoside

  • Determination of CD59 protein in normal human serum by enzyme immunoassay, using octyl-glucoside detergent to release glycosyl-phosphatidylinositol-CD59 from lipid complex [18].
  • A polypeptide of similar molecular mass was immunoprecipitated from radiolabeled octyl glucoside (OG) extract of A72 cells using purified virions, virion-specific antiserum, and protein A. The binding to this polypeptide was decreased but not abolished upon prior treatment of the membrane with V. cholerae neuraminidase [19].
  • The immunochemical properties of the reconstituted oxidase made use of monoclonal antibodies raised against membrane-bound and octyl-glucoside-extracted cytochrome b [20].
  • Purified, delipidated rhodopsin is recombined with phospholipid using octyl-glucoside (OG) and preformed vesicles [21].
  • Membrane vesicles from the multidrug-resistant KB-V1 and KB-C1 cell lines overexpressing P-glycoprotein (Pgp), responsible for pleiotropic chemotherapeutic agents resistance, were solubilized with octyl-glucoside (OG-EX) and further fractionated on DEAE-sepharose column with increased concentrations of NaCl [22].
 

Analytical, diagnostic and therapeutic context of Octyl glucoside

  • The presence of alpha 3 beta 1 was confirmed by Western blots of the OG extract probed with anti-alpha 3 or -beta 1 antibodies [23].
  • We solubilized the glyoxysomal membrane APX (gmAPX) using octyl-glucoside and purified its activity by gel filtration [24].

References

  1. Localization of the African swine fever virus attachment protein P12 in the virus particle by immunoelectron microscopy. Carrascosa, A.L., Saastre, I., González, P., Viñuela, E. Virology (1993) [Pubmed]
  2. Formation of 9-nm filaments from pilin monomers obtained by octyl-glucoside dissociation of Pseudomonas aeruginosa pili. Watts, T.H., Scraba, D.G., Paranchych, W. J. Bacteriol. (1982) [Pubmed]
  3. Isolation and characterization of a structural subunit from the core light-harvesting complex of Rhodobacter sphaeroides 2.4.1 and puc705-BA. Chang, M.C., Meyer, L., Loach, P.A. Photochem. Photobiol. (1990) [Pubmed]
  4. Non-lytic extraction and characterisation of receptors for multiple strains of rotavirus. Jolly, C.L., Beisner, B.M., Ozser, E., Holmes, I.H. Arch. Virol. (2001) [Pubmed]
  5. Interaction of kunjin virus with octyl-D-glucoside extracted Vero cell plasma membrane. Sankaran, D., Lau, L.C., Ng, M.L. J. Virol. Methods (1997) [Pubmed]
  6. Activation of the superoxide-forming NADPH oxidase of macrophages requires two cytosolic components--one of them is also present in certain nonphagocytic cells. Pick, E., Kroizman, T., Abo, A. J. Immunol. (1989) [Pubmed]
  7. Inositol 1,4,5-trisphosphate receptor-like protein in plasmalemmal caveolae is linked to actin filaments. Fujimoto, T., Miyawaki, A., Mikoshiba, K. J. Cell. Sci. (1995) [Pubmed]
  8. Smooth muscle raft-like membranes. Baron, C.B., Coburn, R.F. J. Lipid Res. (2004) [Pubmed]
  9. Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression. Zhang, W.J., Hufnagl, P., Binder, B.R., Wojta, J. Thromb. Haemost. (2003) [Pubmed]
  10. Structure and dynamics of the beta-barrel of the membrane transporter BtuB by site-directed spin labeling. Fanucci, G.E., Cadieux, N., Piedmont, C.A., Kadner, R.J., Cafiso, D.S. Biochemistry (2002) [Pubmed]
  11. Involvement of the cytoskeleton in Junin virus multiplication. Candurra, N.A., Lago, M.J., Maskin, L., Damonte, E.B. J. Gen. Virol. (1999) [Pubmed]
  12. Increased levels of IL-5 positive peripheral blood eosinophils and lymphocytes in mild asthmatics after allergen inhalation provocation. Halldén, G., Hellman, C., Grönneberg, R., Lundahl, J. Clin. Exp. Allergy (1999) [Pubmed]
  13. Protein conformational changes and myelin solubilization by anion-detergent solutions. Monreal, J., Carmona, P., Regueiro, P., Díaz, R.S. FEBS Lett. (1992) [Pubmed]
  14. Isolation and characterization of a subunit form of the B875 light-harvesting complex from Rhodobacter capsulatus. Heller, B.A., Loach, P.A. Photochem. Photobiol. (1990) [Pubmed]
  15. Incorporation of the cytochrome P-450 monooxygenase system into large unilamellar liposomes using octylglucoside, especially for measurements of protein diffusion in membranes. Schwarz, D., Gast, K., Meyer, H.W., Lachmann, U., Coon, M.J., Ruckpaul, K. Biochem. Biophys. Res. Commun. (1984) [Pubmed]
  16. Assembly of light-harvesting chlorophyll a/b complex in vitro. Time-resolved fluorescence measurements. Booth, P.J., Paulsen, H. Biochemistry (1996) [Pubmed]
  17. Interaction of Sendai viral F, HN, and M proteins with host cytoskeletal and lipid components in Sendai virus-infected BHK cells. Sanderson, C.M., Avalos, R., Kundu, A., Nayak, D.P. Virology (1995) [Pubmed]
  18. Determination of CD59 protein in normal human serum by enzyme immunoassay, using octyl-glucoside detergent to release glycosyl-phosphatidylinositol-CD59 from lipid complex. Landi, A.P., Wilson, A.B., Davies, A., Lachmann, P.J., Ferriani, V.P., Seilly, D.J., Assis-Pandochi, A.I. Immunol. Lett. (2003) [Pubmed]
  19. Identification of a 40- to 42-kDa attachment polypeptide for canine parvovirus in A72 cells. Basak, S., Turner, H., Parr, S. Virology (1994) [Pubmed]
  20. Characterization of neutrophil NADPH oxidase activity reconstituted in a cell-free assay using specific monoclonal antibodies raised against cytochrome b558. Batot, G., Martel, C., Capdeville, N., Wientjes, F., Morel, F. Eur. J. Biochem. (1995) [Pubmed]
  21. 2H and 31P nuclear magnetic resonance studies of membranes containing bovine rhodopsin. Albert, A.D., Lane, S.A., Yeagle, P.L. J. Membr. Biol. (1985) [Pubmed]
  22. Differential phosphorylation patterns of P-glycoprotein reconstituted into a proteoliposome system: insight into additional unconventional phosphorylation sites. Lelong-Rebel, I.H., Cardarelli, C.O. Anticancer Res. (2005) [Pubmed]
  23. Identification of the integrin alpha 3 beta 1 as a component of a partially purified A-system amino acid transporter from Ehrlich cell plasma membranes. McCormick, J.I., Johnstone, R.M. Biochem. J. (1995) [Pubmed]
  24. Ascorbate peroxidase, a scavenger of hydrogen peroxide in glyoxysomal membranes. Karyotou, K., Donaldson, R.P. Arch. Biochem. Biophys. (2005) [Pubmed]
 
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