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Chemical Compound Review

Azopt     (2S)-2-ethylamino-4-(3- methoxypropyl)-5,5...

Synonyms: Birnzolamide, Brinzolamide, SureCN24636, CHEMBL220491, CHEBI:3176, ...
 
 

  

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Disease relevance of Brinzolamide

 

High impact information on Brinzolamide

 

Chemical compound and disease context of Brinzolamide

 

Biological context of Brinzolamide

 

Anatomical context of Brinzolamide

 

Associations of Brinzolamide with other chemical compounds

 

Gene context of Brinzolamide

 

Analytical, diagnostic and therapeutic context of Brinzolamide

References

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  2. The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open-angle glaucoma or ocular hypertension. Brinzolamide Primary Therapy Study Group. Sall, K. Survey of ophthalmology. (2000) [Pubmed]
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  9. A randomized, investigator-masked, 4-week study comparing timolol maleate 0.5%, brinzolamide 1%, and brimonidine tartrate 0.2% as adjunctive therapies to travoprost 0.004% in adults with primary open-angle glaucoma or ocular hypertension. Reis, R., Queiroz, C.F., Santos, L.C., Avila, M.P., Magacho, L. Clinical therapeutics. (2006) [Pubmed]
  10. Adjunctive therapy with brinzolamide 1% ophthalmic suspension (Azopt) in patients with open-angle glaucoma or ocular hypertension maintained on timolol therapy. Shin, D. Survey of ophthalmology. (2000) [Pubmed]
  11. Ocular hypotensive efficacy and safety of brinzolamide ophthalmic suspension 1% added to travoprost ophthalmic solution 0.004% therapy in patients with openangle glaucoma or ocular hypertension. Franks, W. Current medical research and opinion. (2006) [Pubmed]
  12. Intraocular pressure lowering effect of brinzolamide 1.0% as adjunctive therapy to latanoprost 0.005% in patients with open angle glaucoma or ocular hypertension: an uncontrolled, open-label study. Shoji, N., Ogata, H., Suyama, H., Ishikawa, H., Suzuki, H., Morita, T., Kawai, H., Nishimoto, H., Nemoto, T., Shimizu, K. Current medical research and opinion. (2005) [Pubmed]
  13. Structural analysis of inhibitor binding to human carbonic anhydrase II. Boriack-Sjodin, P.A., Zeitlin, S., Chen, H.H., Crenshaw, L., Gross, S., Dantanarayana, A., Delgado, P., May, J.A., Dean, T., Christianson, D.W. Protein Sci. (1998) [Pubmed]
  14. Increased optic nerve head blood flow after 1 week of twice daily topical brinzolamide treatment in Dutch-belted rabbits. Barnes, G.E., Li, B., Dean, T., Chandler, M.L. Survey of ophthalmology. (2000) [Pubmed]
  15. Preclinical overview of brinzolamide. DeSantis, L. Survey of ophthalmology. (2000) [Pubmed]
  16. Effects of brinzolamide on ocular haemodynamics in healthy volunteers. Kaup, M., Plange, N., Niegel, M., Remky, A., Arend, O. The British journal of ophthalmology. (2004) [Pubmed]
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  19. Effect of topical brinzolamide 1% and brimonidine 0.2% on intraocular pressure after phacoemulsification. Cetinkaya, A., Akman, A., Akova, Y.A. Journal of cataract and refractive surgery. (2004) [Pubmed]
  20. Comparing the effects of travoprost and brinzolamide on intraocular pressure after phacoemulsification. Ermis, S.S., Ozturk, F., Inan, U.U. Eye (London, England) (2005) [Pubmed]
  21. Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension. Michaud, J.E., Friren, B. Am. J. Ophthalmol. (2001) [Pubmed]
  22. Cost considerations of medical therapy for glaucoma. Fiscella, R.G., Geller, J.L., Gryz, L.L., Wilensky, J., Viana, M. Am. J. Ophthalmol. (1999) [Pubmed]
  23. Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. Vullo, D., Franchi, M., Gallori, E., Pastorek, J., Scozzafava, A., Pastorekova, S., Supuran, C.T. Bioorg. Med. Chem. Lett. (2003) [Pubmed]
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