Disease relevance of Fluorophotometry

• A series of 22 patients with cystic fibrosis (CF) of similar clinical severity (9 with normal carbohydrate tolerance and 13 with insulin-treated fasting hyperglycemia) was examined with quantitative vitreous fluorophotometry [1].
• To assess the effect of glaucoma and timolol on tear secretion, basal tear turnover was measured with fluorophotometry in 13 open-angle glaucoma patients not using any ophthalmic medication, 24 patients using timolol medication daily, and 41 healthy control subjects [2].
• We performed vitreous fluorophotometry using the Fluorotron Master and intravenous fluorescein injection of 14 mg/kg of body weight in 22 normal subjects [3].
• Inflammatory endpoints included clinical inflammation, blood aqueous barrier (BAB) changes measured by particle-scatter and fluorophotometry, corneal edema, and prostaglandin-E2 (PGE2) [4].
• We used vitreous fluorophotometry to supplement standard clinical techniques and fluorescein angiography to study 23 eyes in 12 patients with pars planitis [5].

High impact information on Fluorophotometry

• All patients underwent fundus photography, fluorescein angiography, and vitreous fluorophotometry before treatment and at 3 and 6 mo after treatment [6].
• Vitreous fluorophotometry was performed on pigmented male rats (Piebald strain) 2 weeks after induction of diabetes by streptozotocin [7].
• AHF (by fluorophotometry) increased by 13% (P < 0.05, n = 8) in treated compared with control eyes corrected for baseline [8].
• CONCLUSIONS: Ibopamine is in a specific class of drug, along with pilocarpine, epinephrine, and bimatoprost that in humans increases the rate of aqueous humor flow as measured by fluorophotometry [9].
• METHODS: The effects of topical ibopamine on pupillary diameter, aqueous humor flow measured by fluorophotometry, and intraocular pressure were studied in 24 healthy, blue-eyed humans [9].

Chemical compound and disease context of Fluorophotometry

• Sodium fluorescein, 17 mg/kg body weight, was injected intravenously and ocular fluorophotometry performed 60 and 120 minutes later [10].
• The effect of buflomedil in diabetic retinopathy estimated by ocular fluorophotometry [11].

Biological context of Fluorophotometry

• Noninvasive monitoring of intraocular pharmacokinetics of daunorubicin using fluorophotometry [12].
• In clinical ophthalmology there are two methods for the diagnosis of breakdown of the BRB, fundus fluorescein angiography and vitreous fluorophotometry [13].

Anatomical context of Fluorophotometry

• A double-blind, randomized, placebo-controlled study of the effect of 0.5% topical thymoxamine hydrochloride an alpha-adrenergic antagonist, on the rate of aqueous humor formation in the eyes of 25 normal human subjects was performed with fluorophotometry [14].
• The alteration of the blood-retinal barrier, which was assessed by vitreous fluorophotometry after systemic administration of sodium fluorescein, followed a well-defined pattern [15].
• All patients had fluorophotometry of both eyes 12 to 18 months after surgery to measure the flow of fluorescein from the anterior chamber to the anterior vitreous [16].
• Blood-aqueous barrier disruption, as measured by aqueous fluorophotometry, was statistically significantly diminished in the flurbiprofen group [17].
• There was no significant alteration of the fluorescein concentration in the vitreous body of the controls when vitreous fluorophotometry was repeated after six to seven days [18].

Associations of Fluorophotometry with chemical compounds

• Immediate effect of epinephrine on aqueous formation in the normal human eye as measured by fluorophotometry [19].
• Basal tear turnover and topical timolol in glaucoma patients and healthy controls by fluorophotometry [2].
• The increase of aqueous flow, determined by fluorophotometry, after the onset of darkness was not affected by 0.1% prazosin treatment [20].
• By vitreous fluorophotometry we have shown that there is breakdown of the BRB in chloroquine retinopathy [21].
• Neither PGF2 alpha nor epinephrine altered aqueous flow as measured by fluorophotometry 2 to 6 hr after the fifth dose [22].

Gene context of Fluorophotometry

• Immunohistochemical staining was used to localise the NEP enzyme protein and its neuropeptide substrates and fluorophotometry to measure the corresponding enzyme activities in saliva [23].
• Vitreous fluorophotometry in patients with retinitis pigmentosa [24].
• We used a new computerized procedure to analyze posterior vitreous fluorophotometry scans, obtained with a commercial fluorophotometer (Fluorotron Master Coherent, Palo Alto, Calif), in insulin-dependent diabetic patients and controls [25].
• Preoperative and serial postoperative fluorophotometry was done in 15 eyes that had a Worst-Fechner lens implanted to correct myopia [26].
• In this paper, the binding characteristics of bovine serum albumin (BSA) and phenylfluorone (PF)-molybdenum (Mo(VI)) complex have been studied by fluorophotometry [27].

Analytical, diagnostic and therapeutic context of Fluorophotometry

• A series of 77 patients with overt diabetes and with apparently normal fundi on ophthalmoscopy and fluorescein angiography was examined by vitreous fluorophotometry [28].
• Kinetic vitreous fluorophotometry was performed up to five hours after intravenous injection of fluorescein in seven normal subjects and seven noninsulin-dependent diabetic patients without retinopathy [29].
• Anterior chamber fluorophotometry was performed after the oral administration of fluorescein sodium in patients undergoing extracapsular cataract extraction and posterior chamber intraocular lens insertion before and after surgery [30].
• IOP and AHF were determined, under ketamine anesthesia, by Goldmann applanation tonometry and fluorophotometry, respectively [31].
• PURPOSE: To evaluate the integrity of the aqueous-vitreous barrier by assessing the flow of fluorescein from the anterior chamber to the anterior vitreous using fluorophotometry in eyes with a posterior continuous curvilinear capsulorhexis (PCCC) and in eyes without a PCCC [16].

References