Gene Review:
GPA33 - glycoprotein A33 (transmembrane)
Homo sapiens
Synonyms:
A33, Cell surface A33 antigen, Glycoprotein A33
- Transcriptional regulation of A33 antigen expression by gut-enriched Krüppel-like factor. Mao, Z., Song, S., Zhu, Y., Yi, X., Zhang, H., Shang, Y., Tong, T. Oncogene (2003)
- Micro-sequencing strategies for the human A33 antigen, a novel surface glycoprotein of human gastrointestinal epithelium. Moritz, R.L., Ritter, G., Catimel, B., Cohen, L.S., Welt, S., Old, L.J., Burgess, A.W., Nice, E.C., Simpson, R.J. Journal of chromatography. A. (1998)
- Phase I/II study of iodine 131-labeled monoclonal antibody A33 in patients with advanced colon cancer. Welt, S., Divgi, C.R., Kemeny, N., Finn, R.D., Scott, A.M., Graham, M., Germain, J.S., Richards, E.C., Larson, S.M., Oettgen, H.F. J. Clin. Oncol. (1994)
- Human cytotoxic T-cells suppress the growth of spontaneous melanoma metastases in SCID/hu mice. Sabzevari, H., Reisfeld, R.A. Cancer Res. (1993)
- Relative therapeutic efficacy of (125)I- and (131)I-labeled monoclonal antibody A33 in a human colon cancer xenograft. Barendswaard, E.C., Humm, J.L., O'Donoghue, J.A., Sgouros, G., Finn, R.D., Scott, A.M., Larson, S.M., Welt, S. J. Nucl. Med. (2001)
- A putative zinc-binding protein on lampbrush chromosome loops. Bellini, M., Lacroix, J.C., Gall, J.G. EMBO J. (1993)
- The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily. Heath, J.K., White, S.J., Johnstone, C.N., Catimel, B., Simpson, R.J., Moritz, R.L., Tu, G.F., Ji, H., Whitehead, R.H., Groenen, L.C., Scott, A.M., Ritter, G., Cohen, L., Welt, S., Old, L.J., Nice, E.C., Burgess, A.W. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanized monoclonal antibody A33. Ritter, G., Cohen, L.S., Williams, C., Richards, E.C., Old, L.J., Welt, S. Cancer Res. (2001)
- Phase I/II study of iodine 125-labeled monoclonal antibody A33 in patients with advanced colon cancer. Welt, S., Scott, A.M., Divgi, C.R., Kemeny, N.E., Finn, R.D., Daghighian, F., Germain, J.S., Richards, E.C., Larson, S.M., Old, L.J. J. Clin. Oncol. (1996)
- A phase I trial of humanized monoclonal antibody A33 in patients with colorectal carcinoma: biodistribution, pharmacokinetics, and quantitative tumor uptake. Scott, A.M., Lee, F.T., Jones, R., Hopkins, W., MacGregor, D., Cebon, J.S., Hannah, A., Chong, G., U, P., Papenfuss, A., Rigopoulos, A., Sturrock, S., Murphy, R., Wirth, V., Murone, C., Smyth, F.E., Knight, S., Welt, S., Ritter, G., Richards, E., Nice, E.C., Burgess, A.W., Old, L.J. Clin. Cancer Res. (2005)
- Pharmacokinetics and microdistribution of polyethylene glycol-modified humanized A33 antibody targeting colon cancer xenografts. Deckert, P.M., Jungbluth, A., Montalto, N., Clark, M.A., Finn, R.D., Williams, C., Richards, E.C., Panageas, K.S., Old, L.J., Welt, S. Int. J. Cancer (2000)
- Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium. Ritter, G., Cohen, L.S., Nice, E.C., Catimel, B., Burgess, A.W., Moritz, R.L., Ji, H., Heath, J.K., White, S.J., Welt, S., Old, L.J., Simpson, R.J. Biochem. Biophys. Res. Commun. (1997)
- Comparative metabolism and retention of iodine-125, yttrium-90, and indium-111 radioimmunoconjugates by cancer cells. Press, O.W., Shan, D., Howell-Clark, J., Eary, J., Appelbaum, F.R., Matthews, D., King, D.J., Haines, A.M., Hamann, P., Hinman, L., Shochat, D., Bernstein, I.D. Cancer Res. (1996)
- Enhanced antitumor activity of combination radioimmunotherapy (131I-labeled monoclonal antibody A33) with chemotherapy (fluorouracil). Tschmelitsch, J., Barendswaard, E., Williams, C., Yao, T.J., Cohen, A.M., Old, L.J., Welt, S. Cancer Res. (1997)
- Role of receptor-mediated endocytosis in the formation of vaccinia virus extracellular enveloped particles. Husain, M., Moss, B. J. Virol. (2005)
- Enhancement of radiation dose to the nucleus by vesicular internalization of iodine-125-labeled A33 monoclonal antibody. Daghighian, F., Barendswaard, E., Welt, S., Humm, J., Scott, A., Willingham, M.C., McGuffie, E., Old, L.J., Larson, S.M. J. Nucl. Med. (1996)
- Purification and characterization of a novel restricted antigen expressed by normal and transformed human colonic epithelium. Catimel, B., Ritter, G., Welt, S., Old, L.J., Cohen, L., Nerrie, M.A., White, S.J., Heath, J.K., Demediuk, B., Domagala, T., Lee, F.T., Scott, A.M., Tu, G.F., Ji, H., Moritz, R.L., Simpson, R.J., Burgess, A.W., Nice, E.C. J. Biol. Chem. (1996)
- Glycoprotein A34, a novel target for antibody-based cancer immunotherapy. Scanlan, M.J., Ritter, G., Yin, B.W., Williams, C., Cohen, L.S., Coplan, K.A., Fortunato, S.R., Frosina, D., Lee, S.Y., Murray, A.E., Chua, R., Filonenko, V.V., Sato, E., Old, L.J., Jungbluth, A.A. Cancer Immun. (2006)
- The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies. Rader, C., Ritter, G., Nathan, S., Elia, M., Gout, I., Jungbluth, A.A., Cohen, L.S., Welt, S., Old, L.J., Barbas, C.F. J. Biol. Chem. (2000)