Gene Review:
FTCD - formimidoyltransferase cyclodeaminase
Homo sapiens
Synonyms:
Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, LCHC1
- A formiminotransferase cyclodeaminase isoform is localized to the Golgi complex and can mediate interaction of trans-Golgi network-derived vesicles with microtubules. Hennig, D., Scales, S.J., Moreau, A., Murley, L.L., De Mey, J., Kreis, T.E. J. Biol. Chem. (1998)
- Autoantibody detection in type 2 autoimmune hepatitis using a chimera recombinant protein. Vitozzi, S., Lapierre, P., Djilali-Saiah, I., Alvarez, F. J. Immunol. Methods (2002)
- Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer. Mao, Y., Vyas, N.K., Vyas, M.N., Chen, D.H., Ludtke, S.J., Chiu, W., Quiocho, F.A. EMBO J. (2004)
- A murine model of type 2 autoimmune hepatitis: Xenoimmunization with human antigens. Lapierre, P., Djilali-Saiah, I., Vitozzi, S., Alvarez, F. Hepatology (2004)
- Distinct epitopes on formiminotransferase cyclodeaminase induce autoimmune liver cytosol antibody type 1. Muratori, L., Sztul, E., Muratori, P., Gao , Y., Ripalti, A., Ponti, C., Lenzi, M., Landini, M.P., Bianchi, F.B. Hepatology (2001)
- Cloning and characterization of human FTCD on 21q22.3, a candidate gene for glutamate formiminotransferase deficiency. Solans, A., Estivill, X., de la Luna, S. Cytogenet. Cell Genet. (2000)
- Localization of Golgi 58K protein (formiminotransferase cyclodeaminase) to the centrosome. Hagiwara, H., Tajika, Y., Matsuzaki, T., Suzuki, T., Aoki, T., Takata, K. Histochem. Cell Biol. (2006)
- The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme. Kohls, D., Sulea, T., Purisima, E.O., MacKenzie, R.E., Vrielink, A. Structure (2000)
- Characterization of the B cell response of patients with anti-liver cytosol autoantibodies in type 2 autoimmune hepatitis. Lapierre, P., Johanet, C., Alvarez, F. Eur. J. Immunol. (2003)
- The effect of T cell depletion with Campath-1M on immune reconstitution after chemotherapy and allogeneic bone marrow transplant as treatment for leukaemia. Lowdell, M.W., Craston, R., Ray, N., Koh, M., Galatowicz, G., Prentice, H.G. Bone Marrow Transplant. (1998)
- Characterization of the antigenicity of the formiminotransferase-cyclodeaminase in type 2 autoimmune hepatitis. Renous, R., Lapierre, P., Djilali-Saiah, I., Vitozzi, S., Alvarez, F. Exp. Cell Res. (2004)
- Dissociation of the octameric bifunctional enzyme formiminotransferase-cyclodeaminase in urea. Isolation of two monofunctional dimers. Findlay, W.A., MacKenzie, R.E. Biochemistry (1987)
- Renaturation of formiminotransferase-cyclodeaminase from guanidine hydrochloride. Quaternary structure requirements for the activities and polyglutamate specificity. Findlay, W.A., MacKenzie, R.E. Biochemistry (1988)
- Crystallization and preliminary X-ray analysis of the formiminotransferase domain from the bifunctional enzyme formiminotransferase-cyclodeaminase. Kohls, D., Croteau, N., Mejia, N., MacKenzie, R.E., Vrielink, A. Acta Crystallogr. D Biol. Crystallogr. (1999)