Gene Review:
Krt5 - keratin 5
Mus musculus
Synonyms:
3300001P10Rik, AW146334, CK-5, CK5, Cytokeratin-5, ...
Aoki,
Sawada,
Rogers,
Schweizer,
Shimomura,
Tsujimoto,
Ito,
Ito,
Yoshida,
Hu,
Karin,
Müller-Decker,
Fürstenberger,
Annan,
Kucher,
Pohl-Arnold,
Steinbauer,
Esposito,
Chiblak,
Friess,
Schirmacher,
Berger,
Müller-Decker,
Berger,
Ackermann,
Ehemann,
Zoubova,
Aulmann,
Pyerin,
Fürstenberger,
- Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex. Peters, B., Kirfel, J., Büssow, H., Vidal, M., Magin, T.M. Mol. Biol. Cell (2001)
- Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Teulière, J., Faraldo, M.M., Deugnier, M.A., Shtutman, M., Ben-Ze'ev, A., Thiery, J.P., Glukhova, M.A. Development (2005)
- Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10. Sundberg, J.P., Erickson, A.A., Roop, D.R., Binder, R.L. Cancer Res. (1994)
- Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor. Pérez, P., Page, A., Bravo, A., Del Río, M., Giménez-Conti, I., Budunova, I., Slaga, T.J., Jorcano, J.L. FASEB J. (2001)
- Rapid Development of Salivary Gland Carcinomas upon Conditional Expression of K-ras Driven by the Cytokeratin 5 Promoter. Raimondi, A.R., Vitale-Cross, L., Amornphimoltham, P., Gutkind, J.S., Molinolo, A. Am. J. Pathol. (2006)
- Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival. Sano, S., Takahama, Y., Sugawara, T., Kosaka, H., Itami, S., Yoshikawa, K., Miyazaki, J., van Ewijk, W., Takeda, J. Immunity (2001)
- Preinvasive duct-derived neoplasms in pancreas of keratin 5-promoter cyclooxygenase-2 transgenic mice. Müller-Decker, K., Fürstenberger, G., Annan, N., Kucher, D., Pohl-Arnold, A., Steinbauer, B., Esposito, I., Chiblak, S., Friess, H., Schirmacher, P., Berger, I. Gastroenterology (2006)
- Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder. Li, A.G., Wang, D., Feng, X.H., Wang, X.J. EMBO J. (2004)
- Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network. Kartasova, T., Roop, D.R., Holbrook, K.A., Yuspa, S.H. J. Cell Biol. (1993)
- Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation. Missero, C., Serra, C., Stenn, K., Dotto, G.P. J. Cell Biol. (1993)
- Thymus Medulla Formation and Central Tolerance Are Restored in IKK{alpha}-/- Mice That Express an IKK{alpha} Transgene in Keratin 5+ Thymic Epithelial Cells. Lomada, D., Liu, B., Coghlan, L., Hu, Y., Richie, E.R. J. Immunol. (2007)
- Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia. Cascallana, J.L., Bravo, A., Donet, E., Leis, H., Lara, M.F., Paramio, J.M., Jorcano, J.L., Pérez, P. Endocrinology (2005)
- Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. Klug, D.B., Carter, C., Gimenez-Conti, I.B., Richie, E.R. J. Immunol. (2002)
- In vitro characteristics of early epidermal progenitors isolated from keratin 14 (K14)-deficient mice: insights into the role of keratin 17 in mouse keratinocytes. Troy, T.C., Turksen, K. J. Cell. Physiol. (1999)
- Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice. Reichelt, J., Büssow, H., Grund, C., Magin, T.M. Mol. Biol. Cell (2001)
- Type II keratins precede type I keratins during early embryonic development. Lu, H., Hesse, M., Peters, B., Magin, T.M. Eur. J. Cell Biol. (2005)
- Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium. Darwiche, N., Celli, G., Sly, L., Lancillotti, F., De Luca, L.M. Cancer Res. (1993)
- Cystic duct dilatations and proliferative epithelial lesions in mouse mammary glands upon keratin 5 promoter-driven overexpression of cyclooxygenase-2. Müller-Decker, K., Berger, I., Ackermann, K., Ehemann, V., Zoubova, S., Aulmann, S., Pyerin, W., Fürstenberger, G. Am. J. Pathol. (2005)
- Amelogenin interacts with cytokeratin-5 in ameloblasts during enamel growth. Ravindranath, R.M., Basilrose, R.M., Ravindranath, N.H., Vaitheesvaran, B. J. Biol. Chem. (2003)
- Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Prince, M.E., Sivanandan, R., Kaczorowski, A., Wolf, G.T., Kaplan, M.J., Dalerba, P., Weissman, I.L., Clarke, M.F., Ailles, L.E. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors. Miyoshi, K., Rosner, A., Nozawa, M., Byrd, C., Morgan, F., Landesman-Bollag, E., Xu, X., Seldin, D.C., Schmidt, E.V., Taketo, M.M., Robinson, G.W., Cardiff, R.D., Hennighausen, L. Oncogene (2002)
- IkappaB kinase alpha is essential for development of the mammalian cornea and conjunctiva. Yoshida, K., Hu, Y., Karin, M. Invest. Ophthalmol. Vis. Sci. (2000)
- A novel type II cytokeratin, mK6irs, is expressed in the Huxley and Henle layers of the mouse inner root sheath. Aoki, N., Sawada, S., Rogers, M.A., Schweizer, J., Shimomura, Y., Tsujimoto, T., Ito, K., Ito, M. J. Invest. Dermatol. (2001)
- Real-time monitoring of keratin 5 expression during burn re-epithelialization. Bruen, K.J., Campbell, C.A., Schooler, W.G., deSerres, S., Cairns, B.A., Hultman, C.S., Meyer, A.A., Randell, S.H. J. Surg. Res. (2004)
- Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. Gomperts, B.N., Belperio, J.A., Rao, P.N., Randell, S.H., Fishbein, M.C., Burdick, M.D., Strieter, R.M. J. Immunol. (2006)
- Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity. Yang, X., Cheng, R., Li, C., Cai, W., Ma, J.X., Liu, Q., Yang, Z., Song, Z., Liu, Z., Gao, G. Cancer Biol. Ther. (2006)