Gene Review:
PTRH1 - peptidyl-tRNA hydrolase 1 homolog (S....
Homo sapiens
Synonyms:
C9orf115, PTH, PTH1
- Pamidronate reduces PTH-mediated bone loss in a gene transfer model of hyperparathyroidism in rats. Mitlak, B.H., Rodda, C.P., Von Deck, M.D., Dobrolet, N.C., Neer, R.M., Nussbaum, S.R. J. Bone Miner. Res. (1991)
- Bone-selective analogs of human PTH(1-34) increase bone formation in an ovariectomized rat model. Lane, N.E., Kimmel, D.B., Nilsson, M.H., Cohen, F.E., Newton, S., Nissenson, R.A., Strewler, G.J. J. Bone Miner. Res. (1996)
- Human preproparathyroid hormone synthesized in Escherichia coli is transported to the surface of the bacterial inner membrane but not processed to the mature hormone. Born, W., Freeman, M., Hendy, G.N., Rapoport, A., Rich, A., Potts, J.T., Kronenberg, H.M. Mol. Endocrinol. (1987)
- Somatic gene transfer in the development of an animal model for primary hyperparathyroidism. Wilson, J.M., Grossman, M., Thompson, A.R., Lupassikis, C., Rosenberg, A., Potts, J.T., Kronenberg, H.M., Mulligan, R.C., Nussbaum, S.R. Endocrinology (1992)
- New members of the parathyroid hormone/parathyroid hormone receptor family: the parathyroid hormone 2 receptor and tuberoinfundibular peptide of 39 residues. Usdin, T.B., Wang, T., Hoare, S.R., Mezey, E., Palkovits, M. Frontiers in neuroendocrinology. (2000)
- Paradoxical actions of exogenous and endogenous parathyroid hormone-related protein on renal vascular smooth muscle cell proliferation: reversion in the SHR model of genetic hypertension. Massfelder, T., Taesch, N., Endlich, N., Eichinger, A., Escande, B., Endlich, K., Barthelmebs, M., Helwig, J.J. FASEB J. (2001)
- Structure of tuberoinfundibular peptide of 39 residues. Piserchio, A., Usdin, T., Mierke, D.F. J. Biol. Chem. (2000)
- Autoactivation of type-1 parathyroid hormone receptors containing a tethered ligand. Shimizu, M., Carter, P.H., Gardella, T.J. J. Biol. Chem. (2000)
- Chronic parathyroid hormone administration reverses the antihypertensive effect of calcium loading in young spontaneously hypertensive rats. Kishimoto, H., Tsumura, K., Fujioka, S., Uchimoto, S., Morii, H. Am. J. Hypertens. (1993)
- Parathyroid hormone 1 receptor: insights into structure and function. Chorev, M. Recept. Channels (2002)
- The (1-14) fragment of parathyroid hormone (PTH) activates intact and amino-terminally truncated PTH-1 receptors. Luck, M.D., Carter, P.H., Gardella, T.J. Mol. Endocrinol. (1999)
- Effects of two treatment regimes with synthetic human parathyroid hormone fragment on bone formation and the tissue balance of trabecular bone in greyhounds. Podbesek, R., Edouard, C., Meunier, P.J., Parsons, J.A., Reeve, J., Stevenson, R.W., Zanelli, J.M. Endocrinology (1983)
- Contrasting mammalian parathyroid hormone (PTH) promoters: nuclear factor-Y binds to a deoxyribonucleic acid element unique to the human PTH promoter and acts as a transcriptional enhancer. Alimov, A.P., Langub, M.C., Malluche, H.H., Park-Sarge, O.K., Koszewski, N.J. Endocrinology (2004)
- Histidine at position 5 is the specificity "switch" between two parathyroid hormone receptor subtypes. Behar, V., Nakamoto, C., Greenberg, Z., Bisello, A., Suva, L.J., Rosenblatt, M., Chorev, M. Endocrinology (1996)
- Mutational analysis of the receptor-activating region of human parathyroid hormone. Gardella, T.J., Axelrod, D., Rubin, D., Keutmann, H.T., Potts, J.T., Kronenberg, H.M., Nussbaum, S.R. J. Biol. Chem. (1991)
- Direct in vitro evidence of extracellular Ca2+-induced amino-terminal truncation of human parathyroid hormone (1-84) by human parathyroid cells. Kawata, T., Imanishi, Y., Kobayashi, K., Onoda, N., Takemoto, Y., Tahara, H., Okuno, S., Ishimura, E., Miki, T., Ishikawa, T., Inaba, M., Nishizawa, Y. J. Clin. Endocrinol. Metab. (2005)
- Effects of oxidation of human parathyroid hormone on its biological activity in continuously infused, thyroparathyroidectomized rats. Horiuchi, N. J. Bone Miner. Res. (1988)
- Interactions of growth hormone and parathyroid hormone in renal phosphate, calcium, and calcitriol metabolism and bone remodeling in postmenopausal women. Lieberman, S.A., Holloway, L., Marcus, R., Hoffman, A.R. J. Bone Miner. Res. (1994)
- Arginine 186 in the extracellular N-terminal region of the human parathyroid hormone 1 receptor is essential for contact with position 13 of the hormone. Adams, A.E., Bisello, A., Chorev, M., Rosenblatt, M., Suva, L.J. Mol. Endocrinol. (1998)
- The first international reference preparation of human parathyroid hormone for immunoassay: characterization and calibration by international collaborative study. Zanelli, J.M., Gaines-Das, R.E. J. Clin. Endocrinol. Metab. (1983)
- Quantitative cell membrane-based radioligand binding assays for parathyroid hormone receptors. Hoare, S.R., Usdin, T.B. Journal of pharmacological and toxicological methods. (1999)
- Zinc(II)-mediated enhancement of the agonist activity of histidine-substituted parathyroid hormone(1-14) analogues. Carter, P.H., Gardella, T.J. Biochim. Biophys. Acta (2001)
- Studies of the N-terminal region of a parathyroid hormone-related peptide (1-36) analog: receptor subtype-selective agonists, antagonists, and photochemical cross-linking agents. Carter, P.H., Jüppner, H., Gardella, T.J. Endocrinology (1999)
- Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor. Shimizu, M., Potts, J.T., Gardella, T.J. J. Biol. Chem. (2000)
- Selective and nonselective inverse agonists for constitutively active type-1 parathyroid hormone receptors: evidence for altered receptor conformations. Carter, P.H., Petroni, B.D., Gensure, R.C., Schipani, E., Potts , J.T., Gardella, T.J. Endocrinology (2001)
- Short-term effects of synthetic human parathyroid hormone-(1--34) administration on bone mineral metabolism in osteoporotic patients. Slovik, D.M., Neer, R.M., Potts, J.T. J. Clin. Invest. (1981)
- Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial. Lane, N.E., Sanchez, S., Modin, G.W., Genant, H.K., Pierini, E., Arnaud, C.D. J. Clin. Invest. (1998)
- Teriparatide [PTH(1-34)] strengthens the proximal femur of ovariectomized nonhuman primates despite increasing porosity. Sato, M., Westmore, M., Ma, Y.L., Schmidt, A., Zeng, Q.Q., Glass, E.V., Vahle, J., Brommage, R., Jerome, C.P., Turner, C.H. J. Bone Miner. Res. (2004)
- Circulating intact parathyroid hormone measured by a two-site immunochemiluminometric assay. Brown, R.C., Aston, J.P., Weeks, I., Woodhead, J.S. J. Clin. Endocrinol. Metab. (1987)