Gene Review:
Xrcc6 - X-ray repair complementing defective...
Mus musculus
Synonyms:
5'-dRP/AP lyase Ku70, 5'-deoxyribose-5-phosphate lyase Ku70, 70kDa, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, ...
- Genomic structure and chromosomal assignment of the mouse Ku70 gene. Takiguchi, Y., Kurimasa, A., Chen, F., Pardington, P.E., Kuriyama, T., Okinaka, R.T., Moyzis, R., Chen, D.J. Genomics (1996)
- Growth retardation and leaky SCID phenotype of Ku70-deficient mice. Gu, Y., Seidl, K.J., Rathbun, G.A., Zhu, C., Manis, J.P., van der Stoep, N., Davidson, L., Cheng, H.L., Sekiguchi, J.M., Frank, K., Stanhope-Baker, P., Schlissel, M.S., Roth, D.B., Alt, F.W. Immunity (1997)
- Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo. Ouyang, H., Nussenzweig, A., Kurimasa, A., Soares, V.C., Li, X., Cordon-Cardo, C., Li, W., Cheong, N., Nussenzweig, M., Iliakis, G., Chen, D.J., Li, G.C. J. Exp. Med. (1997)
- A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. Gao, Y., Chaudhuri, J., Zhu, C., Davidson, L., Weaver, D.T., Alt, F.W. Immunity (1998)
- The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Ferguson, D.O., Sekiguchi, J.M., Chang, S., Frank, K.M., Gao, Y., DePinho, R.A., Alt, F.W. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86. Hamer, G., Roepers-Gajadien, H.L., van Duyn-Goedhart, A., Gademan, I.S., Kal, H.B., van Buul, P.P., Ashley, T., de Rooij, D.G. Biol. Reprod. (2003)
- Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region. Katz, D.J., Beer, M.A., Levorse, J.M., Tilghman, S.M. Mol. Cell. Biol. (2005)
- DNA repair factors and telomere-chromosome integrity in mammalian cells. Hande, M.P. Cytogenet. Genome Res. (2004)
- Double strand break rejoining by the Ku-dependent mechanism of non-homologous end-joining. Jeggo, P., Singleton, B., Beamish, H., Priestley, A. C. R. Acad. Sci. III, Sci. Vie (1999)
- Oxidative damage and defective DNA repair is linked to apoptosis of migrating neurons and progenitors during cerebral cortex development in Ku70-deficient mice. Narasimhaiah, R., Tuchman, A., Lin, S.L., Naegele, J.R. Cereb. Cortex (2005)
- Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase. Jin, S., Inoue, S., Weaver, D.T. Carcinogenesis (1998)
- Effect of Ku proteins on IRES-mediated translation. Silvera, D., Koloteva-Levine, N., Burma, S., Elroy-Stein, O. Biol. Cell (2006)
- Flavopiridol, a cyclin-dependent kinase inhibitor, enhances radiosensitivity of ovarian carcinoma cells. Raju, U., Nakata, E., Mason, K.A., Ang, K.K., Milas, L. Cancer Res. (2003)
- Role of DNA-dependent protein kinase in neuronal survival. Chechlacz, M., Vemuri, M.C., Naegele, J.R. J. Neurochem. (2001)
- The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells. Griffin, C., Waard, H., Deans, B., Thacker, J. DNA Repair (Amst.) (2005)
- Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. Manis, J.P., Gu, Y., Lansford, R., Sonoda, E., Ferrini, R., Davidson, L., Rajewsky, K., Alt, F.W. J. Exp. Med. (1998)
- 3,4-Dideoxyglucosone-3-ene induces apoptosis in renal tubular epithelial cells. Justo, P., Sanz, A.B., Egido, J., Ortiz, A. Diabetes (2005)
- Decreased origin usage and initiation of DNA replication in haploinsufficient HCT116 Ku80+/- cells. Sibani, S., Price, G.B., Zannis-Hadjopoulos, M. J. Cell. Sci. (2005)
- Chromosomal localization of the mouse and rat DNA double-strand break repair genes Ku p70 and Ku p80/XRCC5 and their mRNA expression in various mouse tissues. Koike, M., Matsuda, Y., Mimori, T., Harada, Y.N., Shiomi, N., Shiomi, T. Genomics (1996)
- Tissue-specific changes of DNA repair protein Ku and mtHSP70 in aging rats and their retardation by caloric restriction. Um, J.H., Kim, S.J., Kim, D.W., Ha, M.Y., Jang, J.H., Kim, D.W., Chung, B.S., Kang, C.D., Kim, S.H. Mech. Ageing Dev. (2003)