Gene Review:
Pou3f4 - POU domain, class 3, transcription factor 4
Mus musculus
Synonyms:
BRN-4, Brain-4, Brain-specific homeobox/POU domain protein 4, Brn-4, Brn4, ...
- Retroviral gene transfer and sustained expression of human arylsulfatase A. Learish, R., Ohashi, T., Robbins, P.A., Bahnson, A., Boggs, S.S., Patrene, K., Schwartz, B.E., Gieselmann, V., Barranger, J.A. Gene Ther. (1996)
- Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Schonemann, M.D., Ryan, A.K., McEvilly, R.J., O'Connell, S.M., Arias, C.A., Kalla, K.A., Li, P., Sawchenko, P.E., Rosenfeld, M.G. Genes Dev. (1995)
- The sex-linked fidget mutation abolishes Brn4/Pou3f4 gene expression in the embryonic inner ear. Phippard, D., Boyd, Y., Reed, V., Fisher, G., Masson, W.K., Evans, E.P., Saunders, J.C., Crenshaw, E.B. Hum. Mol. Genet. (2000)
- Mutation of the POU-domain gene Brn4/Pou3f4 affects middle-ear sound conduction in the mouse. Samadi, D.S., Saunders, J.C., Crenshaw, E.B. Hear. Res. (2005)
- Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing beta cells. Hussain, M.A., Miller, C.P., Habener, J.F. J. Biol. Chem. (2002)
- POU homeodomain genes and myogenesis. Dominov, J.A., Miller, J.B. Dev. Genet. (1996)
- Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear. Phippard, D., Lu, L., Lee, D., Saunders, J.C., Crenshaw, E.B. J. Neurosci. (1999)
- Regulatory regions from the Brn4 promoter direct LACZ expression to the developing forebrain and neural tube. Heydemann, A., Nguyen, L.C., Crenshaw, E.B. Brain Res. Dev. Brain Res. (2001)
- Binding preferences of the POU domain protein Brain-4: implications for autoregulation. Malik, K.F., Kim, J., Hartman, A.L., Kim, P., Young, W.S. Brain Res. Mol. Brain Res. (1996)
- Delayed induction of p38 MAPKs in reactive astrocytes in the brain of mice after KA-induced seizure. Che, Y., Yu, Y.M., Han, P.L., Lee, J.K. Brain Res. Mol. Brain Res. (2001)
- The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Wang, W., Lufkin, T. Dev. Biol. (2000)
- Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis. Vincent, M., Guz, Y., Rozenberg, M., Webb, G., Furuta, M., Steiner, D., Teitelman, G. Endocrinology (2003)
- Redundant and synergistic effect of Cdx-2 and Brn-4 on regulating proglucagon gene expression. Wang, P., Liu, T., Li, Z., Ma, X., Jin, T. Endocrinology (2006)
- Fetal microchimerism in the maternal mouse brain: a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier? Tan, X.W., Liao, H., Sun, L., Okabe, M., Xiao, Z.C., Dawe, G.S. Stem Cells (2005)
- Abnormal mesenchymal differentiation in the superior semicircular canal of brn4/pou3f4 knockout mice. Sobol, S.E., Teng, X., Crenshaw, E.B. Arch. Otolaryngol. Head Neck Surg. (2005)