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Gene Review

Utp14b  -  UTP14, U3 small nucleolar...

Mus musculus

Synonyms: 4932411L21Rik, Jsd, Juvenile spermatogonial depletion protein, U3 small nucleolar RNA-associated protein 14 homolog B, jsd
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Disease relevance of Utp14b


High impact information on Utp14b


Biological context of Utp14b


Anatomical context of Utp14b


Associations of Utp14b with chemical compounds


Other interactions of Utp14b


Analytical, diagnostic and therapeutic context of Utp14b


  1. UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man. Rohozinski, J., Lamb, D.J., Bishop, C.E. Biol. Reprod. (2006) [Pubmed]
  2. Cryptorchidism rescues spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice. Shetty, G., Weng, C.C. Endocrinology (2004) [Pubmed]
  3. Restoration of spermatogenesis and fertility in azoospermic mutant mice by suppression and reelevation of testosterone followed by intracytoplasmic sperm injection. Tohda, A., Okuno, T., Matsumiya, K., Okabe, M., Kishikawa, H., Dohmae, K., Okuyama, A., Nishimune, Y. Biol. Reprod. (2002) [Pubmed]
  4. Cessation of spermatogenesis in juvenile spermatogonial depletion (jsd/jsd) mice. Kojima, Y., Kominami, K., Dohmae, K., Nonomura, N., Miki, T., Okuyama, A., Nishimune, Y., Okabe, M. International journal of urology : official journal of the Japanese Urological Association. (1997) [Pubmed]
  5. Defect in germ cells, not in supporting cells, is the cause of male infertility in the jsd mutant mouse: proliferation of spermatogonial stem cells without differentiation. Ohta, H., Yomogida, K., Tadokoro, Y., Tohda, A., Dohmae, K., Nishimune, Y. Int. J. Androl. (2001) [Pubmed]
  6. An X-to-autosome retrogene is required for spermatogenesis in mice. Bradley, J., Baltus, A., Skaletsky, H., Royce-Tolland, M., Dewar, K., Page, D.C. Nat. Genet. (2004) [Pubmed]
  7. The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b. Rohozinski, J., Bishop, C.E. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  8. Juvenile spermatogonial depletion (jsd): a genetic defect of germ cell proliferation of male mice. Beamer, W.G., Cunliffe-Beamer, T.L., Shultz, K.L., Langley, S.H., Roderick, T.H. Biol. Reprod. (1988) [Pubmed]
  9. Testosterone inhibits spermatogonial differentiation in juvenile spermatogonial depletion mice. Shetty, G., Wilson, G., Huhtaniemi, I., Boettger-Tong, H., Meistrich, M.L. Endocrinology (2001) [Pubmed]
  10. Mapping of genes for inhibin subunits alpha, beta A, and beta B on human and mouse chromosomes and studies of jsd mice. Barton, D.E., Yang-Feng, T.L., Mason, A.J., Seeburg, P.H., Francke, U. Genomics (1989) [Pubmed]
  11. Spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice with androgen receptor or follicle-stimulating hormone mutations. Shetty, G., Weng, C.C., Porter, K.L., Zhang, Z., Pakarinen, P., Kumar, T.R., Meistrich, M.L. Endocrinology (2006) [Pubmed]
  12. Stimulation of spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mutant mice by gonadotropin-releasing hormone antagonist treatment. Matsumiya, K., Meistrich, M.L., Shetty, G., Dohmae, K., Tohda, A., Okuyama, A., Nishimune, Y. Endocrinology (1999) [Pubmed]
  13. Juvenile spermatogonial depletion (jsd) mutant seminiferous tubules are capable of supporting transplanted spermatogenesis. Boettger-Tong, H.L., Johnston, D.S., Russell, L.D., Griswold, M.D., Bishop, C.E. Biol. Reprod. (2000) [Pubmed]
  14. Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes. Boettger-Tong, H.L., Rohozinski, J., Agoulnik, A.I., Dohmae, K., Nishimune, Y., Levy, N., Bishop, C.E. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  15. Spermatogonia-dependent expression of testicular genes in mice. Tanaka, K., Tamura, H., Tanaka, H., Katoh, M., Futamata, Y., Seki, N., Nishimune, Y., Hara, T. Dev. Biol. (2002) [Pubmed]
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