Chemical Compound Review:
Busulfex 1,4- bis(methylsulfonyloxy)butane
Synonyms:
Myelosan, busulfan, Busulphan, Mylecytan, Myleran, ...
Srivastava,
Poonkuzhali,
Shaji,
George,
Mathews,
Chandy,
Krishnamoorthy,
Barker,
Weisdorf,
DeFor,
Blazar,
Miller,
Wagner,
Urbano-Ispizua,
Rozman,
Pimentel,
Solano,
de la Rubia,
Brunet,
Pérez-Oteiza,
Ferrá,
Zuazu,
Caballero,
Carvalhais,
Díez,
Espigado,
Martínez,
Campilho,
Sanz,
Sierra,
García-Conde,
Montserrat,
Seger,
Gungor,
Belohradsky,
Blanche,
Bordigoni,
Di Bartolomeo,
Flood,
Landais,
Müller,
Ozsahin,
Passwell,
Porta,
Slavin,
Wulffraat,
Zintl,
Nagler,
Cant,
Fischer,
Haddad,
Landais,
Friedrich,
Gerritsen,
Cavazzana-Calvo,
Morgan,
Bertrand,
Fasth,
Porta,
Cant,
Espanol,
Müller,
Veys,
Vossen,
Fischer,
Locatelli,
Nöllke,
Zecca,
Korthof,
Lanino,
Peters,
Pession,
Kabisch,
Uderzo,
Bonfim,
Bader,
Dilloo,
Stary,
Fischer,
Révész,
Führer,
Hasle,
Trebo,
van den Heuvel-Eibrink,
Fenu,
Strahm,
Giorgiani,
Bonora,
Duffner,
Niemeyer,
- Survival of patients with polycythemia vera on busulfan or 32P. Mathé, G. N. Engl. J. Med. (1978)
- Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. Santos, G.W., Tutschka, P.J., Brookmeyer, R., Saral, R., Beschorner, W.E., Bias, W.B., Braine, H.G., Burns, W.H., Elfenbein, G.J., Kaizer, H. N. Engl. J. Med. (1983)
- Endocardial fibrosis following busulfan treatment. Weinberger, A., Pinkhas, J., Sandbank, U., Shaklai, M., de Vries, A. JAMA (1975)
- Sicca syndrome in a patient with toxic reaction to busulfan. Sidi, Y., Douer, D., Pinkhas, J. JAMA (1977)
- Effect of busulfan on oncornavirus-like activity in platelets and chromosomes in polycythemia vera and essential thrombocythemia. Brodsky, I., Fuscaldo, A.A., Erlick, B.J., Fuscaldo, K.E. J. Natl. Cancer Inst. (1977)
- Etoposide in combination with cyclophosphamide and total body irradiation or busulfan as conditioning for marrow transplantation in adults and children. Spitzer, T.R., Peters, C., Ortlieb, M., Tefft, M.C., Torrisi, J., Cahill, R., Gadner, H., Urban, C., Deeg, H.J. Int. J. Radiat. Oncol. Biol. Phys. (1994)
- Cytogenetic effects of myleran in vivo on bone-marrow cells from male mice. Léonard, A., Léonard, E.D. Mutat. Res. (1978)
- In vivo distinction between a target cell for Friend virus (FVP) and murine hematopoietic stem cells. Nasrallah, A.G., McGarry, M.P. J. Natl. Cancer Inst. (1976)
- Oesophageal varices associated with busulphan-thioguanine combination therapy for chronic myeloid leukaemia. Key, N.S., Kelly, P.M., Emerson, P.M., Chapman, R.W., Allan, N.C., McGee, J.O. Lancet (1987)
- Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group. Hehlmann, R., Heimpel, H., Hasford, J., Kolb, H.J., Pralle, H., Hossfeld, D.K., Queisser, W., Löffler, H., Hochhaus, A., Heinze, B. Blood (1994)
- Nonmyeloablative allogeneic stem cell transplantation for the treatment of chronic myeloid leukemia in first chronic phase. Or, R., Shapira, M.Y., Resnick, I., Amar, A., Ackerstein, A., Samuel, S., Aker, M., Naparstek, E., Nagler, A., Slavin, S. Blood (2003)
- Thiotepa, busulfan, and cyclophosphamide: a new preparative regimen for autologous marrow or blood stem cell transplantation in high-risk multiple myeloma. Dimopoulos, M.A., Alexanian, R., Przepiorka, D., Hester, J., Andersson, B., Giralt, S., Mehra, R., van Besien, K., Delasalle, K.B., Reading, C. Blood (1993)
- Acute graft-versus-host disease prophylaxis with methotrexate and cyclosporine after busulfan and cyclophosphamide in patients with hematologic malignancies. von Bueltzingsloewen, A., Belanger, R., Perreault, C., Bonny, Y., Roy, D.C., Lalonde, Y., Boileau, J., Kassis, J., Lavallee, R., Lacombe, M. Blood (1993)
- Busulfan pharmacokinetics using a single daily high-dose regimen in children with acute leukemia. Shaw, P.J., Scharping, C.E., Brian, R.J., Earl, J.W. Blood (1994)
- A cure for murine sickle cell disease through stable mixed chimerism and tolerance induction after nonmyeloablative conditioning and major histocompatibility complex-mismatched bone marrow transplantation. Kean, L.S., Durham, M.M., Adams, A.B., Hsu, L.L., Perry, J.R., Dillehay, D., Pearson, T.C., Waller, E.K., Larsen, C.P., Archer, D.R. Blood (2002)
- Long-term immune reconstitution and outcome after HLA-nonidentical T-cell-depleted bone marrow transplantation for severe combined immunodeficiency: a European retrospective study of 116 patients. Haddad, E., Landais, P., Friedrich, W., Gerritsen, B., Cavazzana-Calvo, M., Morgan, G., Bertrand, Y., Fasth, A., Porta, F., Cant, A., Espanol, T., Müller, S., Veys, P., Vossen, J., Fischer, A. Blood (1998)
- A randomized trial comparing interferon-alpha with busulfan for newly diagnosed chronic myelogenous leukemia in chronic phase. Ohnishi, K., Ohno, R., Tomonaga, M., Kamada, N., Onozawa, K., Kuramoto, A., Dohy, H., Mizoguchi, H., Miyawaki, S., Tsubaki, K. Blood (1995)
- Target cell of the polycythemia-inducing Friend virus: studies with myleran. Fredrickson, T., Tambourin, P., Wendling, F., Jasmin, C., Smajda, F. J. Natl. Cancer Inst. (1975)
- Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Sheridan, W.P., Begley, C.G., Juttner, C.A., Szer, J., To, L.B., Maher, D., McGrath, K.M., Morstyn, G., Fox, R.M. Lancet (1992)
- UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult Leukaemia. Allan, N.C., Richards, S.M., Shepherd, P.C. Lancet (1995)
- Dibromomannitol in the treatment of chronic granulocytic leukemia: a prospective randomized comparison with busulfan. Canellos, G.P., Young, R.C., Neiman, P.E., DeVita, V.T. Blood (1975)
- Lymphoid reconstitution after transplantation of congenic hematopoietic cells in busulfan-treated mice. Yeager, A.M., Shinn, C., Pardoll, D.M. Blood (1991)
- Clobazam for seizure prophylaxis during busulfan chemotherapy. Schwarer, A.P., Opat, S.S., Watson, A.L., Cole-Sinclair, M.F. Lancet (1995)
- Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial. Locatelli, F., Nöllke, P., Zecca, M., Korthof, E., Lanino, E., Peters, C., Pession, A., Kabisch, H., Uderzo, C., Bonfim, C.S., Bader, P., Dilloo, D., Stary, J., Fischer, A., Révész, T., Führer, M., Hasle, H., Trebo, M., van den Heuvel-Eibrink, M.M., Fenu, S., Strahm, B., Giorgiani, G., Bonora, M.R., Duffner, U., Niemeyer, C.M. Blood (2005)
- Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning. Barker, J.N., Weisdorf, D.J., DeFor, T.E., Blazar, B.R., Miller, J.S., Wagner, J.E. Blood (2003)
- In vivo erythropoietin requirements of regenerating erythroid progenitors (BFU-e, CFU-e) in bone marrow of mice. Udupa, K.B., Reissmann, K.R. Blood (1979)
- Busulfan conjugation by glutathione S-transferases alpha, mu, and pi. Czerwinski, M., Gibbs, J.P., Slattery, J.T. Drug Metab. Dispos. (1996)
- Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation. Srivastava, A., Poonkuzhali, B., Shaji, R.V., George, B., Mathews, V., Chandy, M., Krishnamoorthy, R. Blood (2004)
- Hematopoietic cell transplantation in the twitcher mouse. The effects of pretransplant conditioning with graded doses of busulfan. Yeager, A.M., Shinn, C., Shinohara, M., Pardoll, D.M. Transplantation (1993)
- Identification, immunolocalization, regulation, and postnatal development of the lipocalin EP17 (epididymal protein of 17 kilodaltons) in the mouse and rat epididymis. Fouchécourt, S., Lareyre, J.J., Chaurand, P., DaGue, B.B., Suzuki, K., Ong, D.E., Olson, G.E., Matusik, R.J., Caprioli, R.M., Orgebin-Crist, M.C. Endocrinology (2003)
- Murine male germ cell apoptosis induced by busulfan treatment correlates with loss of c-kit-expression in a Fas/FasL- and p53-independent manner. Choi, Y.J., Ok, D.W., Kwon, D.N., Chung, J.I., Kim, H.C., Yeo, S.M., Kim, T., Seo, H.G., Kim, J.H. FEBS Lett. (2004)
- Splenectomy in chronic myeloid leukemia. Wolf, D.J., Silver, R.T., Coleman, M. Ann. Intern. Med. (1978)
- The number of donor CD3(+) cells is the most important factor for graft failure after allogeneic transplantation of CD34(+) selected cells from peripheral blood from HLA-identical siblings. Urbano-Ispizua, A., Rozman, C., Pimentel, P., Solano, C., de la Rubia, J., Brunet, S., Pérez-Oteiza, J., Ferrá, C., Zuazu, J., Caballero, D., Carvalhais, A., Díez, J.L., Espigado, I., Martínez, C., Campilho, F., Sanz, M.A., Sierra, J., García-Conde, J., Montserrat, E. Blood (2001)
- Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000. Seger, R.A., Gungor, T., Belohradsky, B.H., Blanche, S., Bordigoni, P., Di Bartolomeo, P., Flood, T., Landais, P., Müller, S., Ozsahin, H., Passwell, J.H., Porta, F., Slavin, S., Wulffraat, N., Zintl, F., Nagler, A., Cant, A., Fischer, A. Blood (2002)
- The syndrome of hepatic veno-occlusive disease after marrow transplantation. Bearman, S.I. Blood (1995)
- Acute leukemia in polycythemia vera: an analysis of 1638 patients enrolled in a prospective observational study. Finazzi, G., Caruso, V., Marchioli, R., Capnist, G., Chisesi, T., Finelli, C., Gugliotta, L., Landolfi, R., Kutti, J., Gisslinger, H., Marilus, R., Patrono, C., Pogliani, E.M., Randi, M.L., Villegas, A., Tognoni, G., Barbui, T. Blood (2005)