Gene Review:
Mgp - matrix Gla protein
Rattus norvegicus
Synonyms:
MGP, Matrix Gla protein
- Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase. Price, P.A., Fraser, J.D., Metz-Virca, G. Proc. Natl. Acad. Sci. U.S.A. (1987)
- The warfarin embryopathy: a rat model showing maxillonasal hypoplasia and other skeletal disturbances. Howe, A.M., Webster, W.S. Teratology (1992)
- Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene. Kirfel, J., Kelter, M., Cancela, L.M., Price, P.A., Schüle, R. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Biochemical characterization of the serum fetuin-mineral complex. Price, P.A., Nguyen, T.M., Williamson, M.K. J. Biol. Chem. (2003)
- Discovery of a high molecular weight complex of calcium, phosphate, fetuin, and matrix gamma-carboxyglutamic acid protein in the serum of etidronate-treated rats. Price, P.A., Thomas, G.R., Pardini, A.W., Figueira, W.F., Caputo, J.M., Williamson, M.K. J. Biol. Chem. (2002)
- Matrix GLA protein modulates branching morphogenesis in fetal rat lung. Gilbert, K.A., Rannels, S.R. Am. J. Physiol. Lung Cell Mol. Physiol. (2004)
- Lung, heart, and kidney express high levels of mRNA for the vitamin K-dependent matrix Gla protein. Implications for the possible functions of matrix Gla protein and for the tissue distribution of the gamma-carboxylase. Fraser, J.D., Price, P.A. J. Biol. Chem. (1988)
- Bone origin of the serum complex of calcium, phosphate, fetuin, and matrix Gla protein: biochemical evidence for the cancellous bone-remodeling compartment. Price, P.A., Caputo, J.M., Williamson, M.K. J. Bone Miner. Res. (2002)
- The role of Gla proteins in vascular calcification. Shanahan, C.M., Proudfoot, D., Farzaneh-Far, A., Weissberg, P.L. Crit. Rev. Eukaryot. Gene Expr. (1998)
- Glucocorticoid effects on vitamin K-dependent carboxylase activity and matrix Gla protein expression in rat lung. Gilbert, K.A., Rannels, S.R. Am. J. Physiol. Lung Cell Mol. Physiol. (2003)
- A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. Farzaneh-Far, A., Davies, J.D., Braam, L.A., Spronk, H.M., Proudfoot, D., Chan, S.W., O'Shaughnessy, K.M., Weissberg, P.L., Vermeer, C., Shanahan, C.M. J. Biol. Chem. (2001)
- Role of vitamin K in bone metabolism. Vermeer, C., Jie, K.S., Knapen, M.H. Annu. Rev. Nutr. (1995)
- The identification of matrix Gla protein in cartilage. Hale, J.E., Fraser, J.D., Price, P.A. J. Biol. Chem. (1988)
- The amino bisphosphonate ibandronate prevents vitamin D toxicity and inhibits vitamin D-induced calcification of arteries, cartilage, lungs and kidneys in rats. Price, P.A., Buckley, J.R., Williamson, M.K. J. Nutr. (2001)
- Effects of ascorbic acid, calcitriol, and retinoic acid on the differentiation of preosteoblasts. Choong, P.F., Martin, T.J., Ng, K.W. J. Orthop. Res. (1993)
- Developmental expression and hormonal regulation of the rat matrix Gla protein (MGP) gene in chondrogenesis and osteogenesis. Barone, L.M., Owen, T.A., Tassinari, M.S., Bortell, R., Stein, G.S., Lian, J.B. J. Cell. Biochem. (1991)
- Alterations of bone matrix protein mRNA expression in rat aorta in vitro. Hao, H., Hirota, S., Tsukamoto, Y., Imakita, M., Ishibashi-Ueda, H., Yutani, C. Arterioscler. Thromb. Vasc. Biol. (1995)
- Vitamin K-dependent carboxylase: utilization of decarboxylated bone Gla protein and matrix Gla protein as substrates. Engelke, J.A., Hale, J.E., Suttie, J.W., Price, P.A. Biochim. Biophys. Acta (1991)
- Distinct upregulation of extracellular matrix genes in transition from hypertrophy to hypertensive heart failure. Rysä, J., Leskinen, H., Ilves, M., Ruskoaho, H. Hypertension (2005)
- Relationship between immunological rejection and matrix GLA protein in cryopreserved vascular allografts. Kiji, T., Dohi, Y., Nishizaki, K., Sakaguchi, H., Nagasaka, S., Hayata, Y., Yonemasu, K., Taniguchi, S. Transplant. Proc. (2004)