Disease relevance of BCE_4386

• Inorganic polyphosphate in Bacillus cereus: motility, biofilm formation, and sporulation [1].
• Bacteriophage and bacteriophage-like structures carried by Bacillus medusa and their effect on sporulation [2].
• Characterization of sporulation histidine kinases of Bacillus anthracis [3].
• Spore location patterns in sporulating doublets of Bacillus cereus and Bacillus megaterium, derived from single doublet isolates with differing sporulation geometry [4].
• Changes in membrane-associated proteins during sporulation in Bacillus subtilis [5].

High impact information on BCE_4386

• We consider it unlikely that FluG functions in synthesis of glutamine but instead propose that FluG functions as a GSI-related enzyme in synthesizing an extracellular signal directing asexual sporulation and perhaps other aspects of colony growth [6].
• Recent findings indicate that sigmaB also plays an important role in antibiotic resistance, pathogenesis and cellular differentiation processes such as biofilm formation and sporulation [7].
• The PlcR regulon had dramatic effects on the sporulation of a B. anthracis strain containing the virulence plasmid pXO1 [8].
• Thus, sigma(Fah) may link phage gene expression to sporulation of the host [9].
• Influence of Sporulation Medium Composition on Transcription of ger Operons and the Germination Response of Spores of Bacillus cereus ATCC 14579 [10].

Chemical compound and disease context of BCE_4386

• The effects of ethyl picolinate on germination, outgrowth, and sporulation of Bacillus cereus T were studied in a synthetic medium containing glucose [11].
• Influence of glutamate on growth, sporulation, and spore properties of Bacillus cereus ATCC 14579 in defined medium [12].
• A four- to sixfold increase in specific activity of dihydrodipicolinic acid synthase was observed during sporulation of Bacillus cereus [13].
• Biofilm formation and sporulation by Bacillus cereus on a stainless steel surface and subsequent resistance of vegetative cells and spores to chlorine, chlorine dioxide, and a peroxyacetic acid-based sanitizer [14].
• Cephalexin, cefaclor, cefadroxil, and cefotaxime strongly inhibited sporulation of Bacillus cereus ts-4 at 1 microgram/ml [15].

Biological context of BCE_4386

• The rate of conversion varied, being initially slow, most rapid at the time of morphogenesis of the coat layers, and then slow again late in sporulation, coincident with a decrease in intracellular protease activity [16].
• The initiation of sporulation in Bacillus species is regulated by the phosphorelay signal transduction pathway, which is activated by several histidine sensor kinases in response to cellular and metabolic signals [3].
• Insertional inactivation of mbl indicated that this gene is not essential for cell viability or sporulation [17].
• The implication of the apparently species-specific spore ploidy and the influence of the sporulation conditions on spore size and shape are discussed [18].
• The grouping of B. anthracis strains by size and sporulation temperature did not correlate with their respective virulence [19].

Anatomical context of BCE_4386

• The respiratory systems of the mother cells and forespores of Bacillus cereus were compared throughout the maturation stages (III to VI) of sporulation [20].
• Vegetative cell antigens were located on the cell wall and in the cortical region during sporulation [21].

Associations of BCE_4386 with chemical compounds

• The total amount of nitrogen used by the bacteria in YLLG was less than that used by the bacteria in YLHG, although a significant amount of NH4+ was present in the medium throughout sporulation [12].
• Ethyl picolinate specifically inhibited at two stages, outgrowth and sporulation [11].
• The results indicated that the electron transfer capacity during sporulation, dormancy, and germination is related to the menaquinone levels in the membrane [22].
• The consumption of glutamate depended on the initial concentration; in YLLG, all of the glutamate was used early during exponential growth, while in YLHG, almost all of the glutamate was used during sporulation [12].
• The addition of Mg2+ to the sporulation medium did not remove this requirment for sucrose of Mg2+ [23].

Analytical, diagnostic and therapeutic context of BCE_4386

• It was extracted from the sporulation lysate of a phi med-2-minus strain of B. medusa and purified by differential centrifugation [2].
• Phase-contrast and electron microscopy indicate the presence of both a parasporal body and a long filament which are retained after sporulation [24].
• After oral administration of vegetative cells to broiler chicken and weaned piglets, sporulation was detected in all intestinal samples [25].

References