Gene Review:
awd - abnormal wing discs
Drosophila melanogaster
Synonyms:
1084/08, Abnormal wing disks protein, Awd, BcDNA:GM19775, BcDNA:RH27794, ...
- A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Biggs, J., Hersperger, E., Steeg, P.S., Liotta, L.A., Shearn, A. Cell (1990)
- The expression of the Drosophila awd gene during normal development and in neoplastic brain tumors caused by lgl mutations. Timmons, L., Hersperger, E., Woodhouse, E., Xu, J., Liu, L.Z., Shearn, A. Dev. Biol. (1993)
- The enzymatic activity of Drosophila AWD/NDP kinase is necessary but not sufficient for its biological function. Xu, J., Liu, L.Z., Deng, X.F., Timmons, L., Hersperger, E., Steeg, P.S., Veron, M., Shearn, A. Dev. Biol. (1996)
- The amino acid sequence of nucleoside diphosphate kinase I from spinach leaves, as deduced from the cDNA sequence. Nomura, T., Yatsunami, K., Honda, A., Sugimoto, Y., Fukui, T., Zhang, J., Yamamoto, J., Ichikawa, A. Arch. Biochem. Biophys. (1992)
- Drosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development. Dammai, V., Adryan, B., Lavenburg, K.R., Hsu, T. Genes Dev. (2003)
- Analysis of the lethal interaction between the prune and Killer of prune mutations of Drosophila. Biggs, J., Tripoulas, N., Hersperger, E., Dearolf, C., Shearn, A. Genes Dev. (1988)
- Site-directed mutation of Nm23-H1. Mutations lacking motility suppressive capacity upon transfection are deficient in histidine-dependent protein phosphotransferase pathways in vitro. Freije, J.M., Blay, P., MacDonald, N.J., Manrow, R.E., Steeg, P.S. J. Biol. Chem. (1997)
- Nucleoside diphosphate kinase, a source of GTP, is required for dynamin-dependent synaptic vesicle recycling. Krishnan, K.S., Rikhy, R., Rao, S., Shivalkar, M., Mosko, M., Narayanan, R., Etter, P., Estes, P.S., Ramaswami, M. Neuron (2001)
- Targeted recovery of mutations in Drosophila. Bentley, A., MacLennan, B., Calvo, J., Dearolf, C.R. Genetics (2000)
- Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila. Chiadmi, M., Moréra, S., Lascu, I., Dumas, C., Le Bras, G., Véron, M., Janin, J. Structure (1993)
- Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis. Dearolf, C.R., Tripoulas, N., Biggs, J., Shearn, A. Dev. Biol. (1988)
- The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase. Milon, L., Meyer, P., Chiadmi, M., Munier, A., Johansson, M., Karlsson, A., Lascu, I., Capeau, J., Janin, J., Lacombe, M.L. J. Biol. Chem. (2000)
- A cromoglycate binding protein from rat mast cells of a leukemia line is a nucleoside diphosphate kinase. Hemmerich, S., Yarden, Y., Pecht, I. Biochemistry (1992)
- A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase. Engel, M., Véron, M., Theisinger, B., Lacombe, M.L., Seib, T., Dooley, S., Welter, C. Eur. J. Biochem. (1995)
- A Pro/Ser substitution in nucleoside diphosphate kinase of Drosophila melanogaster (mutation killer of prune) affects stability but not catalytic efficiency of the enzyme. Lascu, I., Chaffotte, A., Limbourg-Bouchon, B., Véron, M. J. Biol. Chem. (1992)
- Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium. Moréra, S., Chiadmi, M., LeBras, G., Lascu, I., Janin, J. Biochemistry (1995)
- Post-translational processing of Drosophila nucleoside diphosphate kinase. Stenberg, L.M., Stenflo, J., Holmgren, P., Brown, M.A. Biochem. Biophys. Res. Commun. (2002)
- Molecular characterization of Ciona sperm outer arm dynein reveals multiple components related to outer arm docking complex protein 2. Hozumi, A., Satouh, Y., Makino, Y., Toda, T., Ide, H., Ogawa, K., King, S.M., Inaba, K. Cell Motil. Cytoskeleton (2006)
- The lethal prune/Killer-of-prune interaction of Drosophila causes a syndrome resembling human neurofibromatosis (NF1). Hackstein, J.H. Eur. J. Cell Biol. (1992)
- Purification and characterization of nucleoside diphosphate kinase from the brain of Bombyx mori. Uno, T., Ueno, M., Kikuchi, M., Aizono, Y. Arch. Insect Biochem. Physiol. (2002)
- Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography. Karlsson, A., Mesnildrey, S., Xu, Y., Moréra, S., Janin, J., Véron, M. J. Biol. Chem. (1996)
- Crystallization and preliminary X-ray diffraction studies of nucleoside diphosphate kinase from Dictyostelium discoideum. Dumas, C., Lebras, G., Wallet, V., Lacombe, M.L., Véron, M., Janin, J. J. Mol. Biol. (1991)