Gene Review:
PSMC6 - proteasome (prosome, macropain) 26S...
Homo sapiens
Synonyms:
26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, CADP44, HEL-S-73, P44, ...
- A role for endothelin-2 and its receptors in breast tumor cell invasion. Grimshaw, M.J., Hagemann, T., Ayhan, A., Gillett, C.E., Binder, C., Balkwill, F.R. Cancer Res. (2004)
- RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation. Fromigu??, O., Ha??, E., Modrowski, D., Bouvet, S., Jacquel, A., Auberger, P., Marie, P.J. Cell Death Differ. (2006)
- p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. Ushio-Fukai, M., Alexander, R.W., Akers, M., Griendling, K.K. J. Biol. Chem. (1998)
- Structure of the Expression Site Reveals Global Diversity in MSP2 (P44) Variants in Anaplasma phagocytophilum. Barbet, A.F., Lundgren, A.M., Alleman, A.R., Stuen, S., Bj??ersdorff, A., Brown, R.N., Drazenovich, N.L., Foley, J.E. Infect. Immun. (2006)
- Expression of interleukin-1beta, tumor necrosis factor alpha, and interleukin-6 in human peripheral blood leukocytes exposed to human granulocytic ehrlichiosis agent or recombinant major surface protein P44. Kim, H.Y., Rikihisa, Y. Infect. Immun. (2000)
- Analysis of six relevant toxaphene congeners in biological samples using ion trap MS/MS. Gouteux, B., Lebeuf, M., Trottier, S., Gagné, J.P. Chemosphere (2002)
- Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. Wittamer, V., Franssen, J.D., Vulcano, M., Mirjolet, J.F., Le Poul, E., Migeotte, I., Brézillon, S., Tyldesley, R., Blanpain, C., Detheux, M., Mantovani, A., Sozzani, S., Vassart, G., Parmentier, M., Communi, D. J. Exp. Med. (2003)
- Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. Brunet, A., Roux, D., Lenormand, P., Dowd, S., Keyse, S., Pouysségur, J. EMBO J. (1999)
- Ebp1 isoforms distinctively regulate cell survival and differentiation. Liu, Z., Ahn, J.Y., Liu, X., Ye, K. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Purification, characterization, and immunogenicity of a disulfide cross-linked Plasmodium vivax vaccine candidate antigen, merozoite surface protein 1, expressed in Escherichia coli. Dutta, S., Ware, L.A., Barbosa, A., Ockenhouse, C.F., Lanar, D.E. Infect. Immun. (2001)
- Identification, purification, and characterization of a PA700-dependent activator of the proteasome. DeMartino, G.N., Proske, R.J., Moomaw, C.R., Strong, A.A., Song, X., Hisamatsu, H., Tanaka, K., Slaughter, C.A. J. Biol. Chem. (1996)
- cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family. Fujiwara, T., Watanabe, T.K., Tanaka, K., Slaughter, C.A., DeMartino, G.N. FEBS Lett. (1996)
- Adult human pancreatic duct and islet cells exhibit similarities in expression and differences in phosphorylation and complex formation of the homeodomain protein Ipf-1. Heimberg, H., Bouwens, L., Heremans, Y., Van De Casteele, M., Lefebvre, V., Pipeleers, D. Diabetes (2000)
- Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking. Archer, C.T., Burdine, L., Kodadek, T. Molecular bioSystems. (2005)
- Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha. Ferrari-Amorotti, G., Keeshan, K., Zattoni, M., Guerzoni, C., Iotti, G., Cattelani, S., Donato, N.J., Calabretta, B. Blood (2006)
- Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient. Wysoczynski, M., Reca, R., Ratajczak, J., Kucia, M., Shirvaikar, N., Honczarenko, M., Mills, M., Wanzeck, J., Janowska-Wieczorek, A., Ratajczak, M.Z. Blood (2005)
- Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells. Yu, C., Krystal, G., Varticovksi, L., McKinstry, R., Rahmani, M., Dent, P., Grant, S. Cancer Res. (2002)
- Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases. Kometiani, P., Li, J., Gnudi, L., Kahn, B.B., Askari, A., Xie, Z. J. Biol. Chem. (1998)
- Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells. Gendron, L., Oligny, J.F., Payet, M.D., Gallo-Payet, N. J. Biol. Chem. (2003)
- SMAR1-derived P44 Peptide Retains Its Tumor Suppressor Function through Modulation of p53. Jalota-Badhwar, A., Kaul-Ghanekar, R., Mogare, D., Boppana, R., Paknikar, K.M., Chattopadhyay, S. J. Biol. Chem. (2007)
- Activator complexes containing the proteasomal regulatory ATPases S10b (SUG2) and S6 (TBP1) in different tissues and organisms. Hastings, R., Walker, G., Eyheralde, I., Dawson, S., Billett, M., Mayer, R.J. Mol. Biol. Rep. (1999)
- Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). Goncharova, E.A., Goncharov, D.A., Eszterhas, A., Hunter, D.S., Glassberg, M.K., Yeung, R.S., Walker, C.L., Noonan, D., Kwiatkowski, D.J., Chou, M.M., Panettieri, R.A., Krymskaya, V.P. J. Biol. Chem. (2002)
- The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells. Kessova, I.G., Cederbaum, A.I. J. Pharmacol. Exp. Ther. (2005)
- Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. Termeer, C., Benedix, F., Sleeman, J., Fieber, C., Voith, U., Ahrens, T., Miyake, K., Freudenberg, M., Galanos, C., Simon, J.C. J. Exp. Med. (2002)
- Establishment of the acute myeloid leukemia cell line Kasumi-6 from a patient with a dominant-negative mutation in the DNA-binding region of the C/EBPalpha gene. Asou, H., Gombart, A.F., Takeuchi, S., Tanaka, H., Tanioka, M., Matsui, H., Kimura, A., Inaba, T., Koeffler, H.P. Genes Chromosomes Cancer (2003)
- Hypothermia-induced loss of endothelial barrier function is restored after dopamine pretreatment: role of p42/p44 activation. Brinkkoetter, P.T., Beck, G.C., Gottmann, U., Loesel, R., Schnetzke, U., Rudic, B., Hanusch, C., Rafat, N., Liu, Z., Weiss, C., Leuvinik, H.G., Ploeg, R., Braun, C., Schnuelle, P., van der Woude, F.J., Yard, B.A. Transplantation (2006)