Gene Review:
Rps6ka1 - ribosomal protein S6 kinase, polypeptide A1
Rattus norvegicus
Synonyms:
90 kDa ribosomal protein S6 kinase 1, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, ...
- Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury. Maekawa, N., Abe, J., Shishido, T., Itoh, S., Ding, B., Sharma, V.K., Sheu, S.S., Blaxall, B.C., Berk, B.C. Circulation (2006)
- Angiotensin II stimulates p90rsk in vascular smooth muscle cells. A potential Na(+)-H+ exchanger kinase. Takahashi, E., Abe, J., Berk, B.C. Circ. Res. (1997)
- Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway. Haworth, R.S., McCann, C., Snabaitis, A.K., Roberts, N.A., Avkiran, M. J. Biol. Chem. (2003)
- Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes. Yamazaki, T., Komuro, I., Kudoh, S., Zou, Y., Shiojima, I., Mizuno, T., Takano, H., Hiroi, Y., Ueki, K., Tobe, K. J. Clin. Invest. (1995)
- Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. Silverman, E., Frödin, M., Gammeltoft, S., Maller, J.L. Mol. Cell. Biol. (2004)
- Synergistic regulation of Schwann cell proliferation by heregulin and forskolin. Rahmatullah, M., Schroering, A., Rothblum, K., Stahl, R.C., Urban, B., Carey, D.J. Mol. Cell. Biol. (1998)
- Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system. Ogunshola, O.O., Antic, A., Donoghue, M.J., Fan, S.Y., Kim, H., Stewart, W.B., Madri, J.A., Ment, L.R. J. Biol. Chem. (2002)
- Regulation of an epitope-tagged recombinant Rsk-1 S6 kinase by phorbol ester and erk/MAP kinase. Grove, J.R., Price, D.J., Banerjee, P., Balasubramanyam, A., Ahmad, M.F., Avruch, J. Biochemistry (1993)
- Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling. Sadoshima, J., Qiu, Z., Morgan, J.P., Izumo, S. Circ. Res. (1995)
- Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes. Rosseland, C.M., Wierød, L., Oksvold, M.P., Werner, H., Ostvold, A.C., Thoresen, G.H., Paulsen, R.E., Huitfeldt, H.S., Skarpen, E. Hepatology (2005)
- A novel role for protein phosphatase 2A in receptor-mediated regulation of the cardiac sarcolemmal Na+/H+ exchanger NHE1. Snabaitis, A.K., D'Mello, R., Dashnyam, S., Avkiran, M. J. Biol. Chem. (2006)
- Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain. Heffron, D., Mandell, J.W. Brain Res. Mol. Brain Res. (2005)
- A new cellular signaling mechanism for angiotensin II activation of NF-kappaB: An IkappaB-independent, RSK-mediated phosphorylation of p65. Zhang, L., Ma, Y., Zhang, J., Cheng, J., Du, J. Arterioscler. Thromb. Vasc. Biol. (2005)
- Cholecystokinin stimulates a specific ribosomal S6 kinase in rat pancreatic acini. Sung, C.K., Williams, J.A. Pancreas (1990)
- Skeletal muscle mitogen-activated protein kinases and ribosomal S6 kinases. Suppression in chronic diabetic rats and reversal by vanadium. Hei, Y.J., Chen, X., Pelech, S.L., Diamond, J., McNeill, J.H. Diabetes (1995)
- Insulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathway. De Los Pinos E, n.u.l.l., Fernández De Mattos S, n.u.l.l., Joaquin, M., Tauler, A. Biochem. J. (2001)
- Specificity of action of bisindolylmaleimide protein kinase C inhibitors: do they inhibit the 70kDa ribosomal S6 kinase in cardiac myocytes? Roberts, N.A., Marber, M.S., Avkiran, M. Biochem. Pharmacol. (2004)
- Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats. Hornberger, T.A., Hunter, R.B., Kandarian, S.C., Esser, K.A. Am. J. Physiol., Cell Physiol. (2001)
- Effects of streptozocin-induced diabetes and islet cell transplantation on insulin signaling in rat skeletal muscle. Markuns, J.F., Napoli, R., Hirshman, M.F., Davalli, A.M., Cheatham, B., Goodyear, L.J. Endocrinology (1999)
- Extracellular receptor kinase and cAMP response element binding protein activation in the neonatal rat heart after perinatal cocaine exposure. Sun, L.S., Quamina, A. Pediatr. Res. (2004)
- Regulation of p70S6k, GSK-3beta, and calcineurin in rat striated muscle during aging. Kinnard, R.S., Mylabathula, D.B., Uddemarri, S., Rice, K.M., Wright, G.L., Blough, E.R. Biogerontology. (2005)