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Gene Review

MON1A  -  MON1 secretory trafficking family member A

Homo sapiens

Synonyms: MGC13272, SAND1, Vacuolar fusion protein MON1 homolog A
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Disease relevance of MON1A

  • Images in clinical medicine. Sand as a foreign body [1].
  • Coliphage (< 1 to 1.2 x 10(3)/liter) were found during each quarterly sampling along an offshore transect to the Sand Island waste treatment facility outfall [2].
  • We describe a new species of piroplasm from brown boobies (Sula leucogaster) on Sand Island, Johnston Atoll National Wildlife Refuge, central Pacific. Mean parasitemia in adults and chicks was less than 1%, with the parasitemia in chicks significantly greater than in adults [3].
  • The Israeli Sand Rat (Psammomys obesus) is an excellent polygenic model for the study of obesity and diabetes [4].
  • Familiarity of owners with two traditional methods of surra (trypanosomiasis) diagnosis ('Sand-ball test' and 'Hair-stick test') known to pastorilists was also probed [5].

Psychiatry related information on MON1A


High impact information on MON1A

  • The expanding transcriptome: the genome as the 'Book of Sand' [7].
  • The new oral formulation of cyclosporine (CsA), Neoral (CsA-N), results in increased area under the curve (AUC) and decreased intra- and interindividual variation in blood concentrations and other pharmacokinetic (PK) parameters when compared with the current Sand-immune (CsA-S) formulation [8].
  • Food intake was restricted to 75% of ad libitum levels in 37 male Psammomys obesus (Israeli Sand Rats) from the ages of 4 (weaning) to 10 weeks [9].
  • Perfluorooctane sulfonate (PFOS) was measured in 161 samples of liver, kidney, blood, or egg yolk from 21 species of fish-eating water birds collected in the United States including albatrosses from Sand Island, Midway Atoll, in the central North Pacific Ocean [10].
  • BACKGROUND: Every year, thousands of suburban high school graduates from mid Atlantic states flock to nearby coastal beaches for a long-anticipated rite of passage known as "beach week." Sand, sun, and sea, and also smoking, binge drinking, drugs, and sex, are reported to be dominant themes [11].

Biological context of MON1A

  • The Egyptian Sand Viper (Cerastes cerastes) crude venom and subfractions were, for the first time, shown to induce platelet aggregation with agonist activities present in two subfractions [12].
  • Seedlings were produced by applying half-sib mating scheme on clones originating from two Deliblato Sand populations that were accommodated to common garden conditions [13].
  • A century and a half of the history of the life sciences in ALABAMA. Dr. Marx Edgeworth Lazarus: the Sand Mountain Hermit [14].
  • Exemplars were: Sand Castles: the unreliability of support systems; Tough Boys, Soft Hearts: feeling less powerless with a strong male; Erosion of Trust: the deterioration of trusted kin networks; and Staying the Course: the intergenerational nature of adolescent pregnancy [15].
  • The result of the flow cytometry showed that there was a perturbation on human dental pulp cell cycle progression at the phases of Sand G2M with a dose-dependent manner [16].

Anatomical context of MON1A

  • OBJECTIVE: Tumors located in posterior mediastinum that extends into spinal canal via intervertebral foramen are called as Dumb-bell or Sand-glass tumors [17].
  • The first person to use the testis as a site of transplantation appears to have been Sand, who found in 1919 that an ovary transplanted into the substance of the testis developed follicles [18].
  • METHODS: Sand rats (Psammomys obesus) underwent baseline measurements of VsEPs in response to linear and angular acceleration stimuli and measurement of the auditory nerve and brainstem evoked response (ABR) [19].
  • The thyroid gland of Indian spiny tailed, Sand lizard, Uromastix hardwickii is in the form of a ribbon like structure situated beneath and across the trachea [20].

Associations of MON1A with chemical compounds

  • To validate the method, rats were exposed for 6 h or 3 days to various concentrations of two reference materials: (1) a known fibrogenic material (i.e., aerosolized alpha-quartz silica particles in the form of Berkeley Min-U-Sil (Pennsylvania Glass and Sand Company, Pittsburgh, PA), or (2) carbonyl iron (CI) particles, as a negative control [21].
  • Two types of implants were used (141 titanium plasma-sprayed and 124 Sand-blasted, large-grit, acid-etched) [22].
  • Beach Sand Exploitation Centre at Cox's Bazar, Bangladesh, produces commercial grade concentrations of magnetite, ilmenite, zircon, etc., from the high-grade accumulations available along the beach and foredune of Cox's Bazar [23].
  • Cylinders of Type III gold alloy were sandblasted with either: 50 micron Aluminium Oxide particles (Group 1); CoJet Sand (Group 2); the CoJet System - CoJet Sand followed by application of silane primer (Group 3) [24].
  • DDT, DDD, and DDE in abiotic media and near-shore marine biota from Sand island, Midway Atoll, North Pacific Ocean [25].

Analytical, diagnostic and therapeutic context of MON1A

  • Significant amounts of lignin precursors, commonly postulated to be the major source of DOM, were found only in trace quantities by thermochemolysis/gas chromatography/mass spectrometry of the Norman Landfill and Tomago Sand Bed hydrophobic DOM fractions [26].
  • 2. Sand flathead (Platycephalus bassensis) was given 2-CSA by intraperitoneal injection at 0.15, 1.5, 15 and 75 mg/kg doses and, 4 days later, bile was collected and solvent extracted before and after enzymatic cleavage of conjugates [27].


  1. Images in clinical medicine. Sand as a foreign body. Petitti, N. N. Engl. J. Med. (1997) [Pubmed]
  2. Coliphage and indigenous phage in Mamala Bay, Oahu, Hawaii. Paul, J.H., Rose, J.B., Jiang, S.C., London, P., Xhou, X., Kellogg, C. Appl. Environ. Microbiol. (1997) [Pubmed]
  3. Description and epizootiology of Babesia poelea n. sp. in brown boobies (Sula leucogaster (Boddaert)) on Sand Island, Johnston Atoll, Central Pacific. Work, T.M., Rameyer, R.A. J. Parasitol. (1997) [Pubmed]
  4. Development of obesity and insulin resistance in the Israeli sand rat (Psammomys obesus). Does leptin play a role? Collier, G.R., De Silva, A., Sanigorski, A., Walder, K., Yamamoto, A., Zimmet, P. Ann. N. Y. Acad. Sci. (1997) [Pubmed]
  5. Ethnoveterinary practices of owners of pneumatic-cart pulling camels in Faisalabad City (Pakistan). Muhammad, G., Khan, M.Z., Hussain, M.H., Iqbal, Z., Iqbal, M., Athar, M. Journal of ethnopharmacology. (2005) [Pubmed]
  6. The healer-patient/family relationship in Vonda N. McIntyre's "Of Mist, and Grass, and Sand". Jones, A.H. Perspect. Biol. Med. (1983) [Pubmed]
  7. The expanding transcriptome: the genome as the 'Book of Sand'. Mendes Soares, L.M., Valcárcel, J. EMBO J. (2006) [Pubmed]
  8. Effect of assay methodology on pharmacokinetic differences between cyclosporine Neoral and Sandimmune formulations. Aspeslet, L.J., LeGatt, D.F., Murphy, G., Yatscoff, R.W. Clin. Chem. (1997) [Pubmed]
  9. The effect of dietary energy restriction on body weight gain and the development of noninsulin-dependent diabetes mellitus (NIDDM) in Psammomys obesus. Walder, K., Dascaliuc, C.R., Lewandowski, P.A., Sanigorski, A.J., Zimmet, P., Collier, G.R. Obes. Res. (1997) [Pubmed]
  10. Perfluorooctane sulfonate in fish-eating water birds including bald eagles and albatrosses. Kannan, K., Franson, J.C., Bowerman, W.W., Hansen, K.J., Jones, P.D., Giesy, J.P. Environ. Sci. Technol. (2001) [Pubmed]
  11. Beach week: a high school graduation rite of passage for sun, sand, suds, and sex. Schwartz, R.H., Milteer, R., Sheridan, M.J., Horner, C.P. Archives of pediatrics & adolescent medicine. (1999) [Pubmed]
  12. Cerastes cerastes (Egyptian sand viper) venom induced platelet aggregation as compared to other agonists. Soslau, G., el-Asmar, M.F., Parker, J. Biochem. Biophys. Res. Commun. (1988) [Pubmed]
  13. Variation in survival of Iris pumila L. juvenile plants grown in two nutrient regimes. Tarasjev, A. Genetika (2005) [Pubmed]
  14. A century and a half of the history of the life sciences in ALABAMA. Dr. Marx Edgeworth Lazarus: the Sand Mountain Hermit. Holley, H.L. The Alabama journal of medical sciences. (1977) [Pubmed]
  15. Giving voice to childbearing teens: views on sexuality and the reality of being a young parent. Clifford, J., Brykczynski, K. The Journal of school nursing : the official publication of the National Association of School Nurses. (1999) [Pubmed]
  16. Effect of dental material HEMA monomer on human dental pulp cells. Li, N., Miao, X., Takakuwa, M., Sato, K., Sato, A. Artificial cells, blood substitutes, and immobilization biotechnology. (1999) [Pubmed]
  17. The principles of surgical management in dumbbell tumors. Yüksel, M., Pamir, N., Ozer, F., Batirel, H.F., Ercan, S. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. (1996) [Pubmed]
  18. The testis and tissue transplantation: historical aspects. Setchell, B.P. J. Reprod. Immunol. (1990) [Pubmed]
  19. Functional impairment of the vestibular end organ resulting from impulse noise exposure. Perez, R., Freeman, S., Cohen, D., Sohmer, H. Laryngoscope (2002) [Pubmed]
  20. Seasonal changes in the thyroid gland of Indian spiny tailed, sand lizard, Uromastix hardwickii (Gray) male. Sinha, A.K., Choubey, B.J. Zeitschrift für mikroskopisch-anatomische Forschung. (1981) [Pubmed]
  21. Initiating the risk assessment process for inhaled particulate materials: development of short term inhalation bioassays. Warheit, D.B., Hartsky, M.A. Journal of exposure analysis and environmental epidemiology. (1997) [Pubmed]
  22. Short (8-mm) dental implants in the rehabilitation of partial and complete edentulism: a 3- to 14-year longitudinal study. Romeo, E., Ghisolfi, M., Rozza, R., Chiapasco, M., Lops, D. The International journal of prosthodontics (2006) [Pubmed]
  23. The measurement of radon working levels at a mineral separation pilot plant in Cox's Bazar, Bangladesh. Hamid Khan, M.A., Chowdhury, M.S. Health physics. (2003) [Pubmed]
  24. Influence of surface treatments on the shear bond strength of Panavia 21 to a Type III gold alloy. Aziz, A.A., Tredwin, C.J., Stokes, A., Gill, D.S., Moles, D.R. The European journal of prosthodontics and restorative dentistry. (2006) [Pubmed]
  25. DDT, DDD, and DDE in abiotic media and near-shore marine biota from Sand island, Midway Atoll, North Pacific Ocean. Hope, B.K., Scatolini, S. Bulletin of environmental contamination and toxicology. (2005) [Pubmed]
  26. Terpenoids as major precursors of dissolved organic matter in landfill leachates, surface water, and groundwater. Leenheer, J.A., Nanny, M.A., McIntyre, C. Environ. Sci. Technol. (2003) [Pubmed]
  27. Metabolites of 2-chlorosyringaldehyde in fish bile: indicator of exposure to bleached hardwood effluent. Haritos, V.S., Brumley, C.M., Holdway, D.A., Ahokas, J.T. Xenobiotica (1995) [Pubmed]
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