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MeSH Review

Cochlear Nerve

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Disease relevance of Cochlear Nerve


Psychiatry related information on Cochlear Nerve


High impact information on Cochlear Nerve


Chemical compound and disease context of Cochlear Nerve


Biological context of Cochlear Nerve


Anatomical context of Cochlear Nerve


Associations of Cochlear Nerve with chemical compounds

  • The results also demonstrate, however, that formation of persistent and functional synapses with NM neurons throughout development is not sufficient to induce any axon to assume the calycine form of a cochlear nerve endbulb.(ABSTRACT TRUNCATED AT 250 WORDS)[21]
  • CNQX, given from E8 to E15 or only from E8 to E10, also blocked the 33% neuronal loss in the nucleus magnocellularis (NM) that follows surgical destruction of the otocyst on E3, a procedure that deafferents NM neurons by preventing formation of the cochlear nerve [22].
  • MRI detected a small hyperintense lesion along the acoustic nerve; the lesion decreased in size and then disappeared after steroid treatment [23].
  • This is consistent with a selective action of dopamine transporter inhibitors on auditory nerve activity [24].
  • The effects of intracochlear and systemic furosemide on the properties of single cochlear nerve fibres in the cat [25].

Gene context of Cochlear Nerve


Analytical, diagnostic and therapeutic context of Cochlear Nerve


  1. Expression of nerve growth factor (NGF) receptors in the developing inner ear of chick and rat. von Bartheld, C.S., Patterson, S.L., Heuer, J.G., Wheeler, E.F., Bothwell, M., Rubel, E.W. Development (1991) [Pubmed]
  2. Macrophage colony stimulating factor (M-CSF) protects spiral ganglion neurons following auditory nerve injury: morphological and functional evidence. Yagihashi, A., Sekiya, T., Suzuki, S. Exp. Neurol. (2005) [Pubmed]
  3. Changes in cell proliferation in rat and guinea pig cochlea after aminoglycoside-induced damage. Yamasoba, T., Kondo, K., Miyajima, C., Suzuki, M. Neurosci. Lett. (2003) [Pubmed]
  4. The neonate has a temporary conductive hearing loss due to fluid in the middle ear. Priner, R., Freeman, S., Perez, R., Sohmer, H. Audiol. Neurootol. (2003) [Pubmed]
  5. Ganglionic hamartoma of the intracanalicular acoustic nerve causing sensorineural hearing loss. Hung, T.Y., Litofsky, N.S., Smith, T.W., Megerian, C.A. The American journal of otology. (1997) [Pubmed]
  6. The latency of auditory nerve-brainstem responses in sensorineural hearing loss. Sohmer, H., Kinarti, R., Gafni, M. Archives of oto-rhino-laryngology. (1981) [Pubmed]
  7. Kainic acid injections result in degeneration of cochlear nucleus cells innervated by the auditory nerve. Bird, S.J., Gulley, R.L., Wenthold, R.J., Fex, J. Science (1978) [Pubmed]
  8. Glutamate receptors are selectively targeted to postsynaptic sites in neurons. Rubio, M.E., Wenthold, R.J. Neuron (1997) [Pubmed]
  9. Immunocytochemical localization of aspartate aminotransferase immunoreactivity in cochlear nucleus of the guinea pig. Altschuler, R.A., Neises, G.R., Harmison, G.G., Wenthold, R.J., Fex, J. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  10. Glutamate and aspartate mimic the afferent transmitter in the cochlea. Bobbin, R.P. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1979) [Pubmed]
  11. Neurophysiologic study of olivopontocerebellar atrophy with or without glutamate dehydrogenase deficiency. Chokroverty, S., Duvoisin, R.C., Sachdeo, R., Sage, J., Lepore, F., Nicklas, W. Neurology (1985) [Pubmed]
  12. Dopamine inhibition of auditory nerve activity in the adult mammalian cochlea. Ruel, J., Nouvian, R., Gervais d'Aldin, C., Pujol, R., Eybalin, M., Puel, J.L. Eur. J. Neurosci. (2001) [Pubmed]
  13. Synaptic inputs to stellate cells in the ventral cochlear nucleus. Ferragamo, M.J., Golding, N.L., Oertel, D. J. Neurophysiol. (1998) [Pubmed]
  14. Calcium and calmodulin inhibit phosphorylation of a novel auditory nerve protein. Coling, D.E., Naik, R.M., Schacht, J. Hear. Res. (1994) [Pubmed]
  15. Reciprocal signaling between spiral ganglion neurons and Schwann cells involves neuregulin and neurotrophins. Hansen, M.R., Vijapurkar, U., Koland, J.G., Green, S.H. Hear. Res. (2001) [Pubmed]
  16. Distribution of myo-inositol in the cat cochlear nucleus. Godfrey, D.A., Hallcher, L.M., Laird, M.H., Matschinsky, F.M., Sherman, W.R. J. Neurochem. (1982) [Pubmed]
  17. Hypoplasia of the bony canal for the cochlear nerve in patients with congenital sensorineural hearing loss: initial observations. Fatterpekar, G.M., Mukherji, S.K., Alley, J., Lin, Y., Castillo, M. Radiology. (2000) [Pubmed]
  18. Effects on auditory nerve responses of acetylcholine introduced into scala tympani [proceedings]. Comis, S.D., Leng, G. J. Physiol. (Lond.) (1978) [Pubmed]
  19. Dopaminergic lateral efferent innervation of the guinea-pig cochlea: immunoelectron microscopy of catecholamine-synthesizing enzymes and effect of 6-hydroxydopamine. Eybalin, M., Charachon, G., Renard, N. Neuroscience (1993) [Pubmed]
  20. Role of L-type Ca(2+) channels in transmitter release from mammalian inner hair cells I. Gross sound-evoked potentials. Zhang, S.Y., Robertson, D., Yates, G., Everett, A. J. Neurophysiol. (1999) [Pubmed]
  21. Adaptations of synaptic form in an aberrant projection to the avian cochlear nucleus. Parks, T.N., Taylor, D.A., Jackson, H. J. Neurosci. (1990) [Pubmed]
  22. Prevention of normally occurring and deafferentation-induced neuronal death in chick brainstem auditory neurons by periodic blockade of AMPA/kainate receptors. Solum, D., Hughes, D., Major, M.S., Parks, T.N. J. Neurosci. (1997) [Pubmed]
  23. MRI and brainstem auditory evoked potential evidence of eighth cranial nerve involvement in multiple sclerosis. Bergamaschi, R., Romani, A., Zappoli, F., Versino, M., Cosi, V. Neurology (1997) [Pubmed]
  24. Dopamine transporter is essential for the maintenance of spontaneous activity of auditory nerve neurones and their responsiveness to sound stimulation. Ruel, J., Wang, J., Demêmes, D., Gobaille, S., Puel, J.L., Rebillard, G. J. Neurochem. (2006) [Pubmed]
  25. The effects of intracochlear and systemic furosemide on the properties of single cochlear nerve fibres in the cat. Evans, E.F., Klinke, R. J. Physiol. (Lond.) (1982) [Pubmed]
  26. Roles of fibroblast growth factors in the inner ear. Pickles, J.O., Chir, B. Audiol. Neurootol. (2002) [Pubmed]
  27. Gastrin, cholecystokinin and their precursors in acoustic neuromas. Rehfeld, J.F., van Solinge, W.W., Tos, M., Thomsen, J. Brain Res. (1990) [Pubmed]
  28. Aquaporin 4 expression in the mammalian inner ear and its role in hearing. Mhatre, A.N., Stern, R.E., Li, J., Lalwani, A.K. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  29. Neurotrophic factors in the auditory periphery. Qun, L.X., Pirvola, U., Saarma, M., Ylikoski, J. Ann. N. Y. Acad. Sci. (1999) [Pubmed]
  30. Apoptosis in auditory brainstem neurons after a severe noise trauma of the organ of Corti: intracochlear GDNF treatment reduces the number of apoptotic cells. Aarnisalo, A.A., Pirvola, U., Liang, X.Q., Miller, J., Ylikoski, J. ORL J. Otorhinolaryngol. Relat. Spec. (2000) [Pubmed]
  31. Cortical perfusion response to an electrical stimulation of the auditory nerve in profoundly deaf patients: study with technetium-99m hexamethylpropylene amine oxime single photon emission tomography. Le Scao, Y., Robier, A., Baulieu, J.L., Beutter, P., Pourcelot, L. European journal of nuclear medicine. (1992) [Pubmed]
  32. Neuroprotective effect of riluzole in acute noise-induced hearing loss. Ruel, J., Wang, J., Pujol, R., Hameg, A., Dib, M., Puel, J.L. Neuroreport (2005) [Pubmed]
  33. Toluene and styrene intoxication route in the rat cochlea. Campo, P., Loquet, G., Blachère, V., Roure, M. Neurotoxicology and teratology. (1999) [Pubmed]
  34. Technical modifications to the middle fossa craniotomy approach in removal of acoustic neuromas. Brackmann, D.E., House, J.R., Hitselberger, W.E. The American journal of otology. (1994) [Pubmed]
  35. Hexachlorobenzene, a dioxin-like compound, disrupts auditory function in rat. Hadjab, S., Maurel, D., Cazals, Y., Siaud, P. Hear. Res. (2004) [Pubmed]
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